Very proud to say our Registered Report supporting a causal relationship between age at menarche and adolescent depression is now published in @BMCMedicine. Link: https://t.co/2WwjicrUQs. This was a big team effort spanning the duration of my PhD! A🧵on the process and findings:

Do individuals with mental health disorders exhibit differences of kind or degree? In a new preprint, we present a novel analytic method called Genomic Taxometric Analysis of Continuous and Case-Control data (GTACCC) to help answer this question, and then apply it Major

Are links between prenatal stress and child outcomes causal? Our study suggests associations between maternal stress during pregnancy and birthweight, gestational age, and emotional/behavioral difficulties are largely confounded by shared familial factors. https://t.co/4H0XQVk5Fw

It was a great pleasure, looking forward to meeting you all in person next time!

Two days ago, a lawfirm filed a federal antitrust lawsuit against 6 commercial publishers (incl Elsevier & Wiley) in the federal district court in New York. They allege a 3-part scheme on part of publishers. 🧵 https://t.co/BswKVg5l5G

First PhD paper🎉Stringent Covid-19 measures and quarantines were associated with more mental distress among adolescents. Younger adolescents, those with lower educated parents and those with lower MDD PGS were especially vulnerable

Do grant proposal texts matter for funding decisions? A field experiment Spoiler alert...NO! #Grants #academia

Defending my PhD @Psykologiskinst on May 16th! My trial lecture is entitled "The use of genetic designs for causal inference". Come for Neyman, family studies and MR—stay for @taylorswift13 lyrics and my nephew's causal reasoning (counterfactual is not to come - not recommended)

Very proud to say our Registered Report supporting a causal relationship between age at menarche and adolescent depression is now published in @BMCMedicine. Link: https://t.co/2WwjicrUQs. This was a big team effort spanning the duration of my PhD! A🧵on the process and findings:

Also, a big thank you to the participating families for their contributions to this ongoing cohort study, @Folkehelseinst for collecting these valuable data, my employer @LovisenbergSH and funder @helsesorost

I would like to thank the stellar team of co-authors @RobynWootton @farteinask @becca_lawn @helga_ask Elizabeth Corfield @mariachmagnus1 Ted Reichborn-Kjennerud Per Magnus @oleaandreassen @camisto @mendel_random @nm_davies Alexandra Havdahl & @laurie_jh

What does this mean? Having an earlier age at menarche was linked to problems in specific domains rather than adolescent mental health in general. So, the timing of menarche may contribute to the differentiation of depression from other mental health conditions in adolescence

Results were consistent across a range of sensitivity analyses. However, multivariable Mendelian randomisation analyses suggested confounding by BMI - that is, a higher childhood body size is associated with earlier pubertal development and also with a higher risk of depression

Having an earlier age at menarche was not consistently linked with other mental health problems such as anxiety, conduct disorder, oppositional defiant disorder or ADHD. After accounting for co-occurring depression and other confounding, no other causal links were identified

What did we find? An earlier age at menarche was associated with more symptoms and diagnoses of adolescent depression, and Mendelian randomisation analyses supported the causality of these relationships. Age at menarche did not impact symptoms before puberty, our negative control

The purpose of this format is to avoid false positive findings due to biases that arise from looking at the data before making analytic choices, or only positive findings ending up being published. We did this based on a new wave of data from the fantastic MoBa cohort (N=13.4k)

The Registered Report format divides the publishing process in two: in Stage 1, a detailed study protocol is peer reviewed before data is available; in Stage 2 (if Stage 1 accepted), results are added, but they do not affect the decision to publish, only adherence to the protocol

Today, I’m proud to say, our new paper on assortative mating was published in @NatureComms. (Link: https://t.co/ZHy3tVoVC3). Here are our key findings 🧵:

"Mandatory data and code sharing for research published by The BMJ" This will happen in all journals over the next century (in some fields sooner than in others). https://t.co/TMY2bl3oQK Open Science is a one-way street.

In this new blog, I write about: 1. All that's wrong in academia—including bad papers, broken peer-review, the publishing industry, and precarious contracts. 2. How important it is *not* to become a cynic. 3. And my personal antidotes to cynicism creep. https://t.co/ysowZilfO4