After careful consideration, ASAP will no longer be posting on this platform. We encourage you to follow us on LinkedIn: or on Bluesky:

GP2 is collaborating with individuals worldwide to learn more about the genetic architecture of #ParkinsonsDisease. Want to learn more? Click on the link below to view progress and explore the latest GP2 updates.

@CraggASAP @PD_Progression PD is associated with the accumulation of aggregates. Team Schapira's latest work focuses on mechanisms for reducing the amount of protein aggregates found in cells.

@CraggASAP In their latest pre-print Team Hardy @PD_Progression seeks to determine the genetic risk factors associated with the progression of dementia in some LBD patients.

@CraggASAP Reactive oxygen species (ROS) and ATP energy levels impact aging and neurodegenerative disorders, such as PD. Interested in learning more about how ROS and ATP are regulated? Check out this Team Edwards preprint to learn more!

Team Cragg @craggASAP describes their new platform designed to model neuronal circuits https://www.biorxiv.org/content/10.1101/2023.10.14.562004v1?utm_source=twitter&utm_medium=twitter&utm_campaign&utm_content=ap_qtcoub909e.

Team De Camilli examines the impact of altering PGK1, an enzyme involved in the production of ATP, on axon metabolism and dopaminergic degeneration.

Team Schlossmacher & Team Biederer partnered together to map the expression of alpha-synuclein in the mouse brain, spinal cord, retina, and gut.

Team Biederer mapped the pathology of tau in a mouse model and utilized computational modeling to determine how LRRK2 inhibitors might impact the progression of tau pathology.

ASAP introduces 7 new #PDresearch preprints to explore this month from October!. Read the thread below for highlights. Head to the ASAP bioRxviv channel to dive deeper into the latest #PD knowledge.

We hope to see you at the next installation of the LRRK2 series TODAY Nov. 30th at 10:00 am (PST) with Matthew LaVoie. It is not too late to register using the link below.

Discover November's Protocol Particular's Episode "Assessing Cellular Uptake of Fluorescently-Labeled Polyamines with Mujahid Azfar, MSc", a member of Team Vangheluwe and graduate student at KU Leuven. Episode available to watch on our YouTube channel!

Queen Mary University of London (@QMUL) is NOW HIRING for two positions!. 🟢 GP2 Training Network Administrator.🟢 GP2 Training Network Coordinator. APPLY NOW! Deadline: December 18th. See more:

This month we are celebrating @noatgnuhp, Rosamund Shastry, and Raja Mirujogi from Team Alessi as our November Open Science Champions. They recently published a YouTube video series providing instructions for using their newly developed mass-spec tools.

We're thankful for our network of researchers, participating cohorts, implementing partners, and volunteers who have contributed towards accelerating discoveries in #ParkinsonsDisease 👏

📚ASAP's Year In Review is coming soon! Which accomplishments are you most excited to read about?.

📣 Three new #PD datasets are available on AMP PD. New sets include SN Brain Data, Untargeted Proteomics Data, and targeted Proteomics Data. Terra notebooks & workspaces are also included in this release for these new datasets. View more:

@EliasAdriaensse @martens_sascha @LazarouLab @ThanhNguyen_TNN Team Hurley @AutophaZeke @TheHurleyLab uncovers the high-resolution structure of a protein complex involved in initiating the cell recycling process known as autophagy in one of their recent pre-prints.

Members of Team Hurley, @eliasadriaensse @martens_sascha @LazarouLab @ThanhNguyen_TNN identify a mechanism that regulates the detection of damaged mitochondria

Team Desjardins discusses how mitochondrial DNA enters into the cytosol to trigger cell death in one of their recent pre-prints.