Yuval Avnir
@yuval_avnir
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Profile photo: Image from the RCSB PDB (https://t.co/f9Jnc7vtRA) of PDB ID 5JO4
Israel
Joined November 2017
Drug development in LMICs: could the emerging Indian model usher the southeast Asian region? - The Lancet Regional Health - Southeast Asia
thelancet.com
Low-income and middle-income countries (LMICs) of southeast Asia are passing through a similar phase as India in their tryst with the development of novel drugs. They are beginning to break away from...
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Shock cooling of a red-supergiant supernova at redshift 3 in lensed images | Nature
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Cumulative polarization in conductive interfacial ferroelectrics | Nature
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A spatiotemporally resolved single-cell atlas of the Plasmodium liver stage | Nature
nature.com
Nature - Single-cell RNA sequencing and single-molecule RNA transcript imaging have been used to characterize spatially and temporally resolved mouse liver and parasite expression programmes during...
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Pandemic, epidemic, endemic: B cell repertoire analysis reveals unique anti-viral responses to SARS-CoV-2, Ebola and Respiratory Syncytial Virus
biorxiv.org
Immunoglobulin gene heterogeneity reflects the diversity and focus of the humoral immune response towards different infections, enabling inference of B cell development processes. Detailed composit...
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Tumor-Infiltrating B Lymphocyte Profiling Identifies IgG-Biased, Clonally Expanded Prognostic Phenotypes in Triple-Negative Breast Cancer
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RAPID: A Rep-Seq Dataset Analysis Platform With an Integrated Antibody Database
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Massive surge of mRNA expression of clonal B-cell receptor in patients with COVID-19 - ScienceDirect
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Germline-Dependent Antibody Paratope States and Pairing Specific VH-VL Interface Dynamics
frontiersin.org
Antibodies have emerged as one of the fastest growing classes of biotherapeutic proteins. To improve the rational design of antibodies, we investigate the co...
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Integrated single-cell analysis revealed immune dynamics during Ad5-nCoV immunization | Cell Discovery
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Revealing how variations in antibody repertoires correlate with vaccine responses
biorxiv.org
An important challenge in vaccine development is to figure out why a vaccine succeeds in some individuals and fails in others. Although antibody repertoires hold a key to answering this question,...
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Using de novo assembly to identify structural variation of eight complex immune system gene regions
journals.plos.org
Author summary The human immune system is incredibly versatile underlying its capacity to defend the body against thousands of pathogens. At a molecular level, it recognizes pathogens using large...
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Analysis of B-cell receptor repertoires in COVID-19 patients using deep embedded representations of protein sequences
biorxiv.org
Analyzing B-cell receptor (BCR) repertoires is immensely useful in evaluating one’s immunological status. Conventionally, repertoire analysis methods have focused on comprehensive assessment of...
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REPERTOIRE OF REARRANGED IMMUNOGLOBULIN HEAVY CHAIN GENES IN RUSSIAN PATIENTS WITH B-CELL LYMPHOPROLIFERATIVE DISEASES - ScienceDirect
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Immune2vec: Embedding B/T Cell Receptor Sequences in ℝN Using Natural Language Processing
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Echidna: integrated simulations of single-cell immune receptor repertoires and transcriptomes
biorxiv.org
Single-cell sequencing now enables the recovery of full-length immune repertoires [B cell receptor (BCR) and T cell receptor (TCR) repertoires], in addition to gene expression information. The...
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Antibody Repertoire Analysis of Tumor-Infiltrating B Cells Reveals Distinct Signatures and Distributions Across Tissues
frontiersin.org
The role of B cells in the tumor microenvironment (TME) has largely been under-investigated, and data regarding the antibody repertoire encoded by B cells in...
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Population-wide diversity and stability of serum antibody epitope repertoires against human microbiota | Nature Medicine
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Phenotypic determinism and stochasticity in antibody repertoires of clonally expanded plasma cells
biorxiv.org
The capacity of humoral B cell-mediated immunity to effectively respond to and protect against pathogenic infections is largely driven by the presence of a diverse repertoire of polyclonal antibodies...
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Antibody Upstream Sequence Diversity and Its Biological Implications Revealed by Repertoire Sequencing - ScienceDirect
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