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Timothy de Wet Profile
Timothy de Wet

@timdewet

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MBChB PhD. I like mycobacteria, microscopes and high-throughput genetics. Currently trying to not make a fool of myself in the clinic.

Cape Town, South Africa
Joined July 2009
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@timdewet
Timothy de Wet
5 years
My PhD thesis in 3 minutes - for an online conference, but a nice way to condense each year down into a minute.
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@timdewet
Timothy de Wet
10 months
Is twitter/X still a good place to talk science? I may be looking for a postdoc next year, and it’s previously where I would have started looking.
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@grok
Grok
5 days
What do you want to know?.
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@timdewet
Timothy de Wet
10 months
Jono’s videos are always worth watching!. S.African Syrah & its Global Glow-up | Old Road Wine Co. 12 Mile Syrah 2. via @YouTube.
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@timdewet
Timothy de Wet
1 year
Training clinician scientists in South Africa is possible. But it requires multiple steps we’re not doing. It’s not enough to have an MBChB and a PhD. You need to support integrated postgraduate training and then the shift to independence. None of this happens currently.
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@timdewet
Timothy de Wet
1 year
It’s crazy how much worse GSH has gotten in the 18 months I’ve worked here. Staff shortages, theatre lists cut, no lab IT systems, no functioning lifts, now no PACS for radiology. At our leading academic hospital. And it’s even worse elsewhere.
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@timdewet
Timothy de Wet
1 year
The scale of this security breach is huge. Essentially the entire public sector laboratory infrastructure is down for days to potentially weeks. The impact on patient care is going to be enormous.
@SowetanLIVE
Sowetan LIVE
1 year
The National Health Laboratory Service (NHLS) had a security breach on Friday resulting in servers and data storage being inaccessible and some – including the backup data – being deleted. @J_chabalala .
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@timdewet
Timothy de Wet
1 year
The worst part of working in public healthcare in South Africa at the moment is dealing with patients who have waited 8 hours to see an overworked doctor in an understaffed facility. And then telling them that things are not going to get better - they’re actively getting worse.
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@timdewet
Timothy de Wet
2 years
When you listen to descriptions of the current NHS, it doesn’t sound too different from SA either.
@Poplak
Richard Poplak
2 years
This is a very good piece that, despite some unwelcome contortions, remind us that failing states eventually merge into amorphous lump of globalised shit.
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@timdewet
Timothy de Wet
2 years
I’m becoming increasingly interested in the historical evolution of medical note taking, especially in South Africa, where electronic records are patchily implemented - As @AdamRodmanMD notes in one of his Bedside Rounds episodes, how we document reflects how we think.
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@timdewet
Timothy de Wet
2 years
Are you burnt out, or do you actually just not like being a doctor?.
@_Eric_Reinhart
Eric Reinhart
2 years
Burnout in healthcare—and many other fields—is the discourse du jour. The “wellness” response has been widely panned. Working conditions are appropriately a focus. I’ve tried to emphasize ideological dynamics at play. But what’s often ignored is the place of desire. 1/.
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@timdewet
Timothy de Wet
2 years
Or maybe it’s that tertiary hospitals prioritise registrar teaching, while using interns as clerks and phlebs. I wonder if it’s different elsewhere, especially a secondary level? .Either way, I don’t think any of us have access to journals or UpToDate.
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@timdewet
Timothy de Wet
2 years
Some of that is probably from the rotational structure - when you’re in a department for 2-3 months, there’s relatively little motivation to invest in you.
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@timdewet
Timothy de Wet
2 years
Internship isn’t really about learning; it’s about service provision. Which is not to say that you can’t and don’t learn. Just that it’s not optimised. It’s especially obvious at an academic hospital like GSH, when you have no access to academic resources (eg UpToDate).
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@timdewet
Timothy de Wet
2 years
Proud to see this finally out after 3 years, a pandemic and a return to med school. Hope it’s a good read!.
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onlinelibrary.wiley.com
High-throughput functional genomics combines genetic manipulation with assays and readouts that enable the acquisition of information about gene function at scale.
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@timdewet
Timothy de Wet
2 years
RT @UCTHealthSci: Congratulations to Professor Valerie Mizrahi, Director of @UCTIDM on her election as Fellow of the Royal Society, London,….
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@timdewet
Timothy de Wet
2 years
The HPCSA internship logbook repeatedly misspells the word “pregnancy” as “pregnancynancy”. So I really trust them to regulate the profession and protect the public.
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@timdewet
Timothy de Wet
2 years
I just worked 92 hours in a 7 day stretch, and I would not recommend it. But at least in exchange for the 12 days in a row I’ve worked, I get a single day off. It’s the little things.
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@timdewet
Timothy de Wet
2 years
I don’t love private healthcare. But the inefficiencies within the public sector are insane, and there’s almost no incentive to streamline or optimise systems. And honestly, I don’t think it’s fixable.
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@timdewet
Timothy de Wet
2 years
Beautiful work in a disease-relevant model. Congrats all!.
@maxgabgut
Max Gutierrez
2 years
💥Happy to see this out @NatureMicrobiol today! Very proud of this work from a fantastic team leaded by @berenaylan @EBernard1993 @enricapel @TheCrick and entirely done in the lab: human #macrophages without #autophagy cannot restrict #Mtb and die.🧵 .
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@timdewet
Timothy de Wet
2 years
I’m into my third month of internship, and despite the horrifying hours and occasional frustration, I really like my job. Liking clinical work, as well as science helps keep the idea of the clinician-scientist alive, even if I haven’t worked out yet how I’ll combine them.
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