syenex
@syenex
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power to the scientists! 🔜 genetic medicines vector design lab 🧑💻🧬🦠🧪🧑🔬
Chicago, Boston
Joined July 2022
Prediction: Gene editing will be huge. This is just Internet stocks in 2000.
Not long ago CRISPR was sold as a tool to cure all disease. Here is the current market sentiment. via @statnews
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Every cell in the living world constantly sheds virus-size particles, and these “EVs” are useful for biotechnology. Here we address a key unmet need in EV bioengineering research: counting surface features (accurately)
biorxiv.org
Extracellular vesicles (EVs) play key roles in diverse biological processes, transport biomolecules between cells, and have been engineered for therapeutic applications. A useful EV bioengineering...
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when I was a postdoc w/ George Whitesides at Harvard, George harbored the belief that a hidden driver/requirement of great science was COST.
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investors often prefer technical risk and not market risk, but underwriting the creation of new markets has resulted in many of the best investments of all time PCs in every home, cloud-based data storage, ride sharing "the market is too small" is often a failure of imagination
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The potential of immune cell therapies will depend on continued investment in and improved access to the enabling elements of their complex technology stack https://t.co/UHC4bSxPdm
science.org
Immune cells are being engineered to recognize and respond to disease states, acting as a “living drug” when transferred into patients. Therapies based on engineered immune cells are now a clinical...
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We’re thrilled to be selected by @abbvie for their 2022 AIM award! Great work team! @TheLeonardLab @jdrosanelli @DevinStranford @HaileyEdelstein
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Non-replicating enveloped viral vector, virus like particle, non-viral vesicle, the lines are blurry. Is function/safety all that matters?
quantamagazine.org
Disease-causing viruses and message-carrying vesicles sit at the ends of a spectrum of membranous particles that cells release.
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Hello, World! 🌍🧬 I'm incredibly excited to share this news and thank @janechuprin for leading this effort. Let's make radically free biotech education, beyond the most privileged hubs. https://t.co/ziVgRUKTmv
nucleatehq.medium.com
Nucleate, the nonprofit organization led by academic trainees and dedicated to empowering the next generation of biotech leaders, today…
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Winners… will combine advances in DNA synthesis, high-throughput screening and ML/AI to query the entire search space of possible vector designs… be able to understand how each individual piece of the non-viral vector contributes to its function in vivo
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It’s a good time to expand the vector toolbox and make them available to scientists making new genetic medicines. Let’s go! #bio #tech
kdtventures.medium.com
Today our ability to treat many diseases is limited only by our ability to effectively deliver genetic medicines.
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