STOP2030
@stop2030project
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An international partnership to implement a new two-in-one medicine for #helminthiasis. #beatNTDs
Joined August 2023
#STOP2030 at a glance! โถ Discover our project and meet the partners with our newly launched presentation video. All you need to know about our novel co-formulation for #STH in under 5 minutes โ watch now! https://t.co/TBItcsNcpQ
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This effort, carried out by the STOP2030 Consortium, aims to improve how diseases affecting more than 1.5 billion people are tackled, and to help endemic countries reach their control targets.
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Alejandro Krolewiecki, our PI, will give a pitch on the innovations behind the combination of these two drugs: a new dosing strategy that simplifies logistics, enabling the control of more species, all in a one-per-person tablet that dissolves with saliva.
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Today weโre presenting our fixed-dose co-formulation of ivermectin and albendazole (FDC) at the Innovation Fair 2025 in Brussels โ an event that brings together innovation ecosystems from Europe, Africa, and the Mediterranean.
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A glimpse into the new funding models for #NTDs R&D ๐ As funding drops, agencies and governments are exploring new approaches to ensure sustainable support for innovation and disease control. Read it here
devex.com
A decline in R&D investment in neglected tropical diseases threatens progress toward critical targets. For over 20 years, one nonprofit has led research on lesser-known diseases and is now seeking...
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Improve #NTD programs through social and behavioural change. The NTD NGO Network has released a quick guide to help organisations develop effective, sustainable, and context-appropriate strategies for #NTDcontrol and elimination. Check it out here:
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To improve the lives and health of affected communities, a new treatment needs to be accepted, accessible and effectively implemented. That is why we work to gather extra evidence beyond safety and efficacy. Discover more on our website
stop2030.org
An international partnership to implement a new two-in-one medicine for helminthiasis
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Under the REALISE study, we aim to treat ~20,000 people in Ghana and Kenya, thanks to our partners @_GHSofficial and @KEMRI_Kenya. The evidence we obtain will be crucial to advancing the FDC and making it available to countries around the world.
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Patients in several schools have started receiving treatment, either the FDC or (in the control group) single-dose albendazole. Several years of collaborative work are behind this significant moment for our Consortium.
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The REALISE study, our clinical trial to evaluate the safety in large populations of our fixed-dose coformulation of ivermectin and albendazole (FDC), has reached an important milestone.
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Quick recap from #EDCTPForum2025! Grateful to join this vital meeting advancing the fight against #NTDs. ๐ฉบ Alejandro Krolewiecki spoke on behalf of STOP2030 among many key voices driving change. ๐
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Last week, @DrJulieJ was proud to participate in @MundoSano 's 1st annual Global Health conference in Madrid! She spoke to challenges in NTD elimination programs and solutions such as @stop2030project novel fixed-dose coformulation of ivermectin and albendazole for STH. #beatNTDs
๐ Ayer celebramos en Madrid la primera Conferencia Anual sobre #SaludGlobal, un encuentro con expertos internacionales para debatir sobre los retos que plantea la eliminaciรณn de #NTDs y las soluciones que podemos aportar para afrontarlos ๐งตโ๐
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๐ Great news! The @EMA_News has issued a positive opinion for a new treatment for parasitic worm infections! ๐ค This achievement is the result of a decade-long collaboration between @MundoSano, @InsudPharma and @EDCTP . ๐Check the article https://t.co/HvEB5HOaZT
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According to the latest WHOโs progress report, more than half of the school-aged children in need of STH treatments received coverage by preventive #chemotherapy campaigns in 2023. Thatโs over 354 million children treated all over the world!
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Discover our co-formulation ๐ Fixed-dose, mouth-dissolving and easy to administer ๐ฅญ Mango-flavoured ใฐ Covers all STH species considered in WHOโs Roadmap ๐ Proven efficacy and safety ๐ฆ And getting ready for implementation Stay tuned for the start of our phase IV trial!
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Our partners at @_GHSofficial recently hosted a key stakeholder meeting towards the implementation of paediatric #praziquantel against #schistosomiasis. Our colleague Dr. Joseph Opare shares valuable insights on the impact and next steps
undp.org
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Our most important results to date, explained in under 2 min ๐ฌ Our phase II-III clinical trial ALIVE demonstrated our co-formulation is safe, and has superior efficacy against more species than the current standard. See why it matters ๐
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86 countries required preventive chemotherapy for soil-transmitted #helminths in 2023 ๐ According to the latest Progress Report published by WHO, over 800 millionchildren worldwide needed treatment for #parasiticworms. Get the data in detail here
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Innovations in #NTDcontrol are constantly emerging, particularly in technology. But how effective are these tools? These researchers have explored how advancements in #AI, robotics, and diagnostics are being tested and implemented in Africa
nature.com
Nature Communications - Countries in Africa facing sociopolitical instability also bear a high burden of neglected tropical diseases (NTDs). Here, the authors explore the potential of health...
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#Strongyloides stercoralis was the last species to be included as a soil-transmitted helminth by WHO. What sets it apart? ๐ฌ Requires a different diagnostic technique (Baermann) ๐ Presents a unique life cycle ๐ And its treatment of choice is #ivermectin
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2025 marks the 5๏ธโฃ0๏ธโฃ-year anniversary of the discovery of #ivermectin, an essential drug to treat many #NTDs, including #strongyloidiasis A fixed-dose strategy for ivermectin can simplify treatment while reducing the risk of underdosing. Read our story
stop2030.org
The quest to find optimal treatment strategies for Neglected Tropical Diseases (NTDs) has been ongoing for many years. In the case of Soil-Transmitted Helminthiasis (STH), which involves five...
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