Stephane Castel
@stephanecastel
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Geneticist, co-founder at @VariantBio and @FiixSoftware, PhD @CSHL, postdoc @nygenome and @Columbia.
Seattle, WA
Joined July 2008
Honored for @VariantBio to have been featured by @SoftBank in their Sōzō Insights series.
“They’re solving the biggest bottleneck that exists in drug discovery.” -- John Xue, SoftBank Investment Advisers (for more, read the recent Sōzō Insights feature piece highlighting Variant Bio's unique approach to drug discovery):
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Summary stats are public; individual-level WGS/RNA-seq data available via controlled access on the EGA. If it’s useful for your research, apply. We want it to have broad impact!
github.com
South African Blood Regulatory Resource. Contribute to variant-bio/SABR development by creating an account on GitHub.
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Our SABR manuscript is out in Nature Genetics. SABR is the largest functional genomics dataset from a continental African cohort. We mapped the genetic architecture of blood expression, splicing, and cell types in over 600 individuals from 3 SEB groups. https://t.co/zZKWM2Po1r
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Variant Bio visits long-term partners in the Faroe Islands to celebrate the end of participant recruitment and kick off data generation together:
medium.com
Visiting long-term partners in the Faroe Islands to celebrate the end of participant recruitment and kick off data generation together
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Listen to Seattle's NPR coverage of Variant Bio's new partnership with Novo Nordisk and our approach to making human genomic research and drug discovery both more ethical and equitable:
kuow.org
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I will be at #JPM25 next week - don't hesitate to reach out if you'd like to connect. Looking forward to an exciting week!
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Our advisor @KeoluFox sharing news of Variant Bio's ground-breaking partnership with Novo Nordisk during a keynote at the Pacific Symposium on Biocomputing (PSB) 2025 in Hawaii this week
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The collaboration between @VariantBio and @novonordisk will trigger our long term benefit sharing program for the first time! Read about it in the NYT.
nytimes.com
Variant Bio, a small biotech company based in Seattle, is using genetic information from Indigenous people to develop drugs for obesity and diabetes.
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Excited to share that @VariantBio is partnering with @novonordisk to identify metabolic disease targets. This gives us the opportunity to translate more findings into treatments that will have a real world impact for patients.
medium.com
We are collaborating with Novo Nordisk to discover novel targets for the treatment of metabolic disease
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How Variant Bio and the Pukapuka Community Group returned group-level results from a collaborative genomic research study in Auckland:
medium.com
How Variant Bio and the Pukapuka Community Group returned group-level results from a collaborative genomic research study in Auckland
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We recently met with partners and community leaders in New Caledonia to conclude one of Variant Bio’s largest studies to date:
medium.com
We recently met with partners and community leaders in New Caledonia to conclude one of Variant Bio’s largest studies to date
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Congratulations to Olivia Gray from Variant Bio and all of our colleagues who received an abstract award @GeneticsSociety last week! #ASHG2024
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Last week, Sarah LeBaron von Baeyer from @VariantBio gave a plenary talk at the BIO2024 Conference at the @UPTuks Future Africa campus in Pretoria, South Africa based on our recent Commentary in Cell. In case you missed it, read the full publication here: https://t.co/uajGrTaFYz
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How Variant Bio is leveraging multi-omics data from studies with diverse populations to boost drug discovery and development:
medium.com
How Variant Bio is leveraging multi-omics data from studies with diverse populations to boost drug discovery and development
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This week Jaye Moors presented on behalf of Variant Bio at the PRECISE-IHCC Conference in Singapore, where she had a great time meeting up with long-time collaborators from the Mochtar Riady Institute for Nanotechnology in Indonesia!
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Huge thanks to Maui Hudson for the inspiring and thought-provoking talk he gave to the team at Variant Bio!
Highlights from a talk marking the 30th anniversary of International Day of the World’s Indigenous Peoples:
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Isabella has been a phenomenal member of the @VariantBio team during her time as a Standley Fellow. This very exciting collaboration in Indonesia wouldn't have been possible without her!
Isabella Apriyana discusses her experiences coordinating a genomic research collaboration between MRIN in Indonesia and Variant Bio:
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It is an honor to see a case study from Variant Bio and research on gout carried out in French Polynesia featured in the latest report from @Policy_Projects. Read more in the press release and download the full report here 👉 https://t.co/xupwxEhVxp
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Wonderful to be in conversation with bioethicists from around the world when presenting about Variant Bio’s approach to genomic research and drug discovery at this week’s World Congress of Bioethics in Doha, Qatar #WCB2024
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Seeing in person how an ongoing project in the Faroe Islands will lead to genomic findings and improve health:
medium.com
Seeing in person how an ongoing project in the Faroe Islands will lead to genomic findings and improve health
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