Spencer Szczesny Profile
Spencer Szczesny

@spence_sz3

Followers
984
Following
518
Media
43
Statuses
399

Investigating the crosstalk between tissue mechanics and mechanobiology that drives tendon/ligament remodeling during degeneration, repair, and development

State College, PA
Joined March 2009
Don't wanna be here? Send us removal request.
@spence_sz3
Spencer Szczesny
5 months
RT @NadeenChahine: NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report. NIH awards supported 407,782 jobs and tran….
0
23
0
@spence_sz3
Spencer Szczesny
5 months
Exciting paper that replicates the hierarchical mechanics of tendon and other soft tissues in a hydrogel, further establishing the role of interfacial sliding as an effective toughening mechanism in biology
0
1
5
@spence_sz3
Spencer Szczesny
5 months
Excited that my first paper in engineering education has been published in the journal Biomedical Engineering Education. It studied the impact of adding content on inequality and bias into BME curricula on women's intent to persist in BME post-graduation.
Tweet card summary image
link.springer.com
Biomedical Engineering Education - While women earn an equal proportion of undergraduate degrees in biomedical engineering, there is a significant decline in female representation at the graduate...
0
1
11
@spence_sz3
Spencer Szczesny
9 months
Excited to publish this comprehensive assessment of tendon structure-function relationships during development using a battery of experimental and computational approaches! Great collaborating with @rolfera @Prof_H_McCarthy @njdunne_lab @DrNiamhBuckley @PennStateBME @mcanonicco.
@ActaBio
Acta Biomaterialia
9 months
Professor Spencer Szczesny: Structural determinants of tendon multiscale mechanics and their sensitivity to mechanical stimulation during development in an embryonic chick model.@BenPetersonMGH.@spence_sz3 .@PennStateBME .@pharmacyatQUB.@DCU.@TCDZoology.
Tweet media one
0
1
24
@spence_sz3
Spencer Szczesny
1 year
Congrats to @krishna1996 and @paschall_lauren for expertly presenting their work at another great @ORSsociety Annual Meeting! @ors_tendon @PennStateBME
Tweet media one
Tweet media two
0
2
25
@spence_sz3
Spencer Szczesny
1 year
1
0
10
@spence_sz3
Spencer Szczesny
1 year
For all @ors_tendon and education fans at #ORS2024, please come check out our talks and poster presentations this Saturday, Sunday, and Tuesday @ORSsociety @krishna1996 @paschall_lauren @PennStateBME
Tweet media one
0
9
33
@spence_sz3
Spencer Szczesny
2 years
Tweet media one
0
1
7
@spence_sz3
Spencer Szczesny
2 years
Congrats to @krishna1996! Very proud of you and what you have accomplished during your PhD! Thanks for all your hard work getting the lab off the ground. Excited to continue to see you at future conferences and hear about you work at @HSpecialSurgery
Tweet media one
Tweet media two
1
1
25
@spence_sz3
Spencer Szczesny
2 years
Congrats to @krishna1996 for successfully defending his dissertation on an explant model of tendon degeneration! It's been a long journey but very proud of him and his accomplishments. Also great to see that big smile again!
Tweet media one
0
3
19
@spence_sz3
Spencer Szczesny
2 years
Congrats to @paschall_lauren for her first pub on the sex-specific mechanobiology of ACL explants! Very exciting work suggesting a novel mechanobiological mechanism for increased ACL ruptures in women. @Tabdanov @Hrsheysportsdoc @PennStateBME @PennStOrtho
Tweet card summary image
pubmed.ncbi.nlm.nih.gov
Anterior cruciate ligament (ACL) injuries are historically thought to be a result of a single acute overload or traumatic event. However, recent studies suggest that ACL failure may be a consequence...
0
8
29
@spence_sz3
Spencer Szczesny
2 years
Calling all MSK researchers: @PennStOrtho is hiring a new Vice Chair of Research to head all research activities within the Ortho dept. as well as the Center for Orthopaedic Research and Translational Sciences. Follow the link for more info and to apply:
1
6
6
@spence_sz3
Spencer Szczesny
2 years
This was the scene at today’s “lab meeting” for which my grad students prepared a celebration for my tenure announcement. So grateful to have the opportunity to do great science with even better people! @krishna1996 @paschall_lauren @mcanonicco and Maggs. 💕
Tweet media one
Tweet media two
5
2
56
@spence_sz3
Spencer Szczesny
2 years
Just got the news that I've been granted tenure and promoted to Associate Professor @PennStateBME. Thank you to all my graduate students, mentors (@dawn_m_elliott @RobertMauck11), and colleagues who helped me make it! I am so appreciative of your support and effort! ❤️.
46
4
191
@spence_sz3
Spencer Szczesny
2 years
Congrats to @krishna1996 on his second paper! Although mouse Achilles tendons degenerate with fatigue loading, he found that they exhibit very little collagen denaturation, suggesting that this damage mechanism does not initiate tendon degeneration.
3
4
23
@spence_sz3
Spencer Szczesny
2 years
Of course, publishing an open-source code in a journal that most institutions don't have access to is sort of silly. So we also posted the code and instructions for use on the MathWorks File Exchange: Hope people find it helpful!.
1
0
8
@spence_sz3
Spencer Szczesny
2 years
I know that measuring local tissue strains in tendon is not new, BUT we just published a validated open-source MATLAB code that anyone can use: Additionally, the code will tell you if the strain fields are inaccurate without knowing the true strains!.
2
9
52
@spence_sz3
Spencer Szczesny
2 years
It was a great pleasure working with David Corr at RPI on this perspective article providing a review and recommendations for tendon cell and tissue culture. Thanks to everyone at the 2022 Tendon Section meeting that helped contribute. Truly a team effort!
Tweet card summary image
onlinelibrary.wiley.com
The wide variety of cell and tissue culture systems used to study and engineer tendons can make it difficult to choose the best approach and “optimal” culture conditions to test a given hypothesis....
0
2
21
@spence_sz3
Spencer Szczesny
2 years
Had such a great time at #ORS2023! Great to meet up with colleagues, learn a lot, and have fun. I’m a little sad to go home from one of the best annual meetings ever! @rolfera @BenPetersonMGH @krishna1996 @mcanonicco @DrNiamhBuckley @ors_tendon
Tweet media one
Tweet media two
2
2
40
@spence_sz3
Spencer Szczesny
2 years
If interested, come check out our work on YAP signaling during tendon development and studying tendon degeneration in an ex vivo model. Poster Session 1, Papers # 1151, 1163, and 2151.
1
0
8