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Reshma Shetty Profile
Reshma Shetty

@reshmapshetty

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Co-founder at Ginkgo Bioworks (@Ginkgo, $DNA)

Joined November 2011
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@Ginkgo
Ginkgo Bioworks
4 months
Ginkgo Datapoints is excited to announce a transformative strategic partnership with Tangible Scientific and Inductive Bio. The partnership is aimed at significantly accelerating drug discovery through the seamless integration of AI-driven lab-in-the-loop workflows. This
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prnewswire.com
/PRNewswire/ -- Ginkgo Bioworks (NYSE: DNA), which is building the leading platform for cell programming and biosecurity, today announced that its Datapoints...
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@jrkelly
Jason Kelly
5 months
Ginkgo's modular automation has been on a tear lately! We are able to install our modular automation INSIDE a large anaerobic chamber for Pacific Northwest National Laboratory (PNNL)! Really excited for the scale of experimentation they will be able to do to advance science
@Ginkgo
Ginkgo Bioworks
5 months
Ginkgo Automation is proud to support the Environmental Molecular Sciences Laboratory (EMSL) at Pacific Northwest National Laboratory (PNNL) in accelerating microbial research to power the bioeconomy. Through this collaboration, Ginkgo will deploy flexible, modular automation
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@Ginkgo
Ginkgo Bioworks
5 months
Ginkgo Automation is proud to support the Environmental Molecular Sciences Laboratory (EMSL) at Pacific Northwest National Laboratory (PNNL) in accelerating microbial research to power the bioeconomy. Through this collaboration, Ginkgo will deploy flexible, modular automation
prnewswire.com
/PRNewswire/ -- Ginkgo Bioworks (NYSE: DNA), which is building the leading platform for cell programming and biosecurity, today announced that the...
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@Ginkgo
Ginkgo Bioworks
5 months
⭕ Circular RNA developed at Ginkgo. Validated by pharma. Available to you today! We're excited to launch CIRQ, a new circular RNA R&D service from Ginkgo, designed to solve the persistent challenges with traditional mRNA—stability, immunogenicity, and scalable manufacturing.
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ginkgo.bio
Build autonomous labs to accelerate biotech R&D. Program biology like software. Run experiments on our cloud lab or build your own. Trusted by 130+ customers.
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@Ginkgo
Ginkgo Bioworks
5 months
Cell-free protein synthesis systems, optimized at Ginkgo and now available to you! Ginkgo has been using cell-fee protein synthesis systems in house for years, and we’re now making our E. coli system available to outside users! We’ve optimized it for: • High production from
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reagents.ginkgo.bio
Ginkgo’s cell free protein synthesis (CFPS) kit is an E. coli transcription/translation system optimized to produce proteins from a T7 RNA Polymerase promoter.  Reactions consist of a bacterial cell...
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@Ginkgo
Ginkgo Bioworks
5 months
We’re excited to launch a powerful new capability at Ginkgo Datapoints: high-throughput, low-cost ADME profiling—optimized for machine learning from day one. Whether you’re prioritizing small molecules or training predictive models, early access to rich ADME data can
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datapoints.ginkgo.bio
Ginkgo Datapoints delivers reliable data solutions and AI-powered tools to accelerate drug discovery and development in the biotech industry.
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@jrkelly
Jason Kelly
5 months
Great article from @voxdotcom on biological weapons and how to defend against them - with commentary from @matt_f_mcknight who leads biodefense work at @Ginkgo. We need to be proactive about this in USG so we aren’t defenseless. https://t.co/gldbBoHP6Y
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vox.com
AI could make bioweapons more dangerous. It could also be the key to stopping them.
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@reshmapshetty
Reshma Shetty
6 months
Thank you @OliverVarhelyi for your visit to @Ginkgo to talk about how we can ensure that everyone can reap the benefits of biotechnology while safeguarding people, livestock and crops from emerging biothreats.
@OliverVarhelyi
Oliver Varhelyi
6 months
My visit to Ginkgo Bioworks showed a good example that biotech innovation and biosecurity go hand in hand. This way, we can deliver on innovative solutions while being ready to counteract emerging threats.
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@lood_ml
Lood van Niekerk
7 months
Excited to expand this further with bigger datasets! They're presenting at the following times: Thursday May 15 10:30-11:15AM 12:25-1:55PM Poster session C Poster hashtag #C044 Feel free to reach out to datapoints@ginkgobioworks.com if you want to know more! (4/4)
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@lood_ml
Lood van Niekerk
7 months
We successfully guide towards these properties while maintaining high naturalness (likelihood) scores under other models such as AbLang2. We've found SVDD ( https://t.co/Xgg7WATw9E) to work better than other discrete diffusion guidance approaches. (3/4)
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@lood_ml
Lood van Niekerk
7 months
We guide antibodies towards low hydrophobicity and polyreactivity using simple oracles trained on 250 antibodies from our latest preprint ( https://t.co/cQNF8HYjYA) (2/4)
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biorxiv.org
Antibodies must bind their targets with high affinity and specificity to achieve useful therapeutic activity. They must also possess additional properties—collectively referred to as developability...
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@lood_ml
Lood van Niekerk
7 months
My colleagues Joshua Moller & Porfirio Quintero @Ginkgo are presenting our poster on guided discrete diffusion for antibody developability tomorrow at PEGS Boston 🧵 (1/4)
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@jrkelly
Jason Kelly
7 months
Executive order out yesterday taking a firm stance against risky gain of function research and the development of biological weapons. If we want to ensure that other countries aren't developing biological weapons we can't just trust them -- we need to be monitoring for it.
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@p_maverick_b
Patrick Boyle — e/🦀
7 months
Excited to share @Ginkgo 's third functional genomics dataset release, GDPx3 - a cell painting dataset featuring 3 primary cell lines and the A549 human lung adenocarcinoma cell line. 220 GB of imaging data, with additional data available to license:
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@jrkelly
Jason Kelly
7 months
GDPx3 features comprehensive morphological profiles for 46 compounds! What makes this dataset uniquely valuable? It provides critical dose-response data across three PRIMARY human cell types with two timepoints (24 hrs, 48 hrs), plus a widely used cell line. 🔬🦠 Aortic Smooth
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datapoints.ginkgo.bio
Ginkgo Datapoints delivers reliable data solutions and AI-powered tools to accelerate drug discovery and development in the biotech industry.
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@jrkelly
Jason Kelly
7 months
Another day, another free data set! Awesome cell painting data on 46 compounds in dose response across 3 primary human cell types + A549s. Download the dataset below! 👇
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@BiologyAIDaily
Biology+AI Daily
8 months
A high-throughput platform for biophysical antibody developability assessment to enable AI/ML model training 1. PROPHET-Ab is a high-throughput platform developed by Ginkgo Bioworks to systematically assess antibody developability and generate ML-ready datasets at
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@jrkelly
Jason Kelly
8 months
Great new resource for anyone working on antibody CMC, developability, or discovery. New preprint out today from Ginkgo that benchmarks 246 therapeutic IgGs across 10 developability assays. The resulting dataset is ML-ready and publicly available. If you're thinking about early
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