@profvrr
Careful interpretation is needed 1) the 2 study cohorts are quite different in terms of age & case severity 2) d0 is admission date not disease onset- the treatment group may be further ahead in disease progression - in the pharynx, virus levels decline naturally after one week.
@profvrr
@profpathogen1
That is impressive. There are other treatments in pipeline. Reason for optimism and researchers that often compete are now working together.
@profvrr
Arbidol, an approved anti-flu drug, which inhibits many other viruses including Ebola, Lassa, and coronas, is also showing encouraging results in studies in China:
@profvrr
@DrMFKearney
Encouraging, but note that all 6 patients excl'd from analysis were on treatment arm (4 for reasons suggesting growth of the infection). Effect size decreases if they are considered. I transcribed all data from Suppl. Table 1:
We are in the midst of reviewing this pre-print, and I'm frankly flabbergasted to see it published virtually unchanged in a journal. A gross failure of peer review in my opinion.