PipeBio (now Benchling)
@pipe_bio
Followers
227
Following
82
Media
58
Statuses
103
Building cloud-based bioinformatics software for antibody discovery and engineering. Now a part of @Benchling.
Aarhus, Denmark
Joined October 2019
🎉 We’re excited to announce that @benchling has acquired PipeBio!. Together with Benchling, we’ll continue delivering innovation in bioinformatics for biologics discovery and more — on an open digital platform that’s connected to the rest of your R&D.
0
2
6
RT @benchling: It’s Times Square official! This week, we announced our acquisition of @pipe_bio. 🙌. Together, we will offer a complete soft….
0
1
0
In collaboration with @Bruker Cellular Analysis, we have analyzed data from a study to detect antigen-specific and cross-reactive antibodies against vascular endothelial growth factor receptor (VEGFR) antigens in an immunized mouse. Read more here👇 .
pipebio.com
Combining single cell heavy and light chain NGS sequences with functional assays to accelerate decision making toward promising leads
0
0
0
Understanding vaccine responses and designing effective vaccines relies on high-resolution immune profiling and antibody repertoire analysis using NGS. Check out the link below to learn more!🔬🧫🧬 . #antibody #vaccines #bioinformatics.
pipebio.com
An overview of next generation techniques for vaccine development, from immune monitoring to in-depth profiling of adaptive immune repertoires
0
0
1
In case you missed it! We saw a total of 16 global first approvals and 10 FDA/EMA first approvals of therapeutic antibodies in 2023 (slightly fewer than in 2022). See full infographic here:.
0
0
1
What is antibody developability, how is it quantified and how can it be predicted?🔬🤖. Read more about silico predictors leveraging machine learning to make the discovery process faster and leaner:. #antibody #ML #drugdiscovery.
0
0
1
How can you use public antibody data to accelerate antibody discovery and engineering?. Read more about data mining in antibody development here👇 . #antibody #data #engineering.
pipebio.com
How combining public and proprietary data can help accelerate antibody discovery and development
0
0
0
Native pairing of antibody heavy-light chains is important for retaining functional antibodies, a challenge with short-read NGS. Read more on our blog on techniques and protocols used for retaining native pairing using NGS👇. #ngs #antibody #drugdiscovery.
pipebio.com
Techniques for retaining native pairing of antibody heavy (VH) and light (VL) chains with NGS sequencing
0
1
7
Next stop on the trail is Lisbon as we're running into PEGS Europe in little over a week!. Looking forward to some great talks (and good runs👟) over there!. #PEGSEurope #Antibody #Athletes
0
0
1
0
0
2
How can you use UMIs to mitigate errors in Antibody / TCR sequencing?. Read more on correcting errors and biases that arise from PCR amplification and sequencing to differentiate "real" clones and true biological diversity. #UMIs #Immunology #NGS.
0
2
10
Rational design and in silico tools together with in vitro validation are some of the hallmark techniques used to select developable antibodies with optimized properties for specific therapeutic targets 👇 . #antibodydiscovery #drugdiscovery.
pipebio.com
From in vivo and in vitro to in silico design of antibody libraries for optimal developability and biophysical properties
0
0
2
What do these images have in common?. PipeBio – and the passion for science that unites our team!👩🔬🔬. Our distinct backgrounds ranging from wet labs to computer engineering make us a strong team and empowers us to find solutions for our customers, fast.
pipebio.com
The PipeBio team comes from a variety of different backgrounds, the passion for science uniting everyone
0
1
3
Early detection of liabilities for developability such as aggregation is quintessential in antibody discovery. See our blog for an overview of a range of tools for antibody aggregation prediction🖥️🔬. #antibody #drugdiscovery.
pipebio.com
In this article we review computational methods for antibody structure and aggregation prediction and show example applications on PipeBio
0
0
1
Circling back to the origins of our logo, we (finally!) got around to implementing the Circos plot ⭕. Great for interactive visualization of larger repertoires, heavy/light or alpha/beta pairings, gene usage and more🙂. #antibody #visualization #Circos
0
0
3
When you can do something, why wouldn't you?🤷 . We at least like trying out ALL possible features 😉 . #antibody #phylogeny #drugdiscovery
0
1
2
Here's a short weekend read on some of the most common cloning techniques used in antibody discovery and engineering🦠👇. #antibody #cloning #drugdevelopment.
0
1
3
The most prominent in vitro display technologies in #antibody discovery and engineering arguably include phage display, yeast display, mammalian display, bacterial display and ribosome display🔬. Here's a short read on our blog: #biologics #drugdiscovery.
0
3
5
An overview of one of the hallmark in vitro selection technologies used for antibody discovery: Phage Display👇 . (adapted from Ledsgaard et al. 2022, full ref. see bottom of graphic). #phage #biologics #drugdiscovery #antibody #antibodydiscovery #drugdevelopment #antibodies
0
2
5