As a scientist, David is laser-focused on developing protein design as a platform. The moment a design goal becomes well-established, he pushes the lab to move on to new modalities. For example, for a long time, the goal was to make proteins that could bind to other proteins. But

@paultkim_ipd There was a detail I was wrapping my head around for some time. Collaboration. How do you make that work? How do you start it, choose what's worth a group effort, what tools or forums allow it any insight in those directions is invaluable for one that considers this shift (me)

@LChoshen There isn't really a formal process. People talk, bring up ideas to David, talk more, and eventually start working on a project.

@paultkim_ipd Thank you for sharing! I’ve always been curious how David’s operation runs. If you don’t mind me asking, what are examples of cognitive load that are offloaded?

@Soumees I think the best example is hiring Lynda Stewart to be the IPD's executive director: https://t.co/lMmi1sY9Rn She is crazy competent and effective (and a great person all around). She handles big picture lab development and future plans, external partnerships, funding, VC

@paultkim_ipd „Funding is almost never a bottleneck.“ But how was that at the beginning?

@gudrun_lotze I don't know as I joined the lab just two years ago but I assume resources were much more constrained

@paultkim_ipd 'and have our own computational cluster with 919 GPUs and counting (primarily A100s, A4000s, A6000s, and L40s).' 🤯 and I'm here showing off the 8 GPUs we have, everytime someone comes to visit... 😅

@paultkim_ipd It’s funny, i don’t believe we’ve ever met—different streams— but you managed to summarize my musings about my time in the Baker lab in this as well 🫶🏿 kudos

@paultkim_ipd Wonderful you shared this

@paultkim_ipd Really nice description of the IPD community!!!

@paultkim_ipd Thank you for the insights. For smaller labs difficult because of resources. Money makes the world go round and drives science.