Patrick Lundgren
@patrlundgren
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Looking for outliers @hummingbirdvc. Keeping track of how little I know.
Boston, MA
Joined September 2017
Thinking that the world needs more thoughtfully crazy people. Most people are just plain crazy or just plain thoughtful.
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RT @hanna_haya: If you're building:.Deeptech: me.Fintech: @akshay__mehra .Bio: @patrlundgren .Generalist EU: @nikitaandersso3 .Healthcare:….
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Interesting: "We found that 1) people from cultures with short sleep durations do not suffer from more negative health outcomes; 2) the optimal amount of sleep duration varies between cultures, and 3) people whose sleep duration is closer to their cultural ideals enjoy better.
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Here is a plot on %GDP spent on pharmaceuticals in 2022 from this link: USA at around 2% of GDP with all European countries (except Greece) below 1.7%. Sweden at 1% of GDP. Norway and Denmark at 0.6%. Meanwhile almost 1% of EU GDP is spent on alcohol. See
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Really strange that this is even controversial. Europe needs to do better. I say this as a native Swede.
remarks from pascal, ceo of Astra, on their earnings call this morning that sums up current state of eu drug market well: "the US has been funding innovation for our industry for a long time. and we believe that europe has to invest a greater share of their healthcare expenses,.
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Why do these threads on cost-effectiveness never mention the fact that drugs go generic?.
@Medscape Unless someone could, you know, negotiate with the drug companies of pharmacy benefit managers to reduce the cost of these drugs so they become cost-effective. One can dream, I suppose. .
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RT @AppleHelix: PSA:. Thanks to Roche/Genentech and Amgen scientists, these 2 papers have probably the most extensive immunogenicity (ADA%)….
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So in tech they are also rebranding from platform co to asset co.
🚨🚨🚨BREAKING: . Microsoft CEO was just asked about the future of building foundational models . “I do believe the models are getting commoditized. OpenAI is not a model company it’s a product company. ” . LMFAOOO
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Reminds me of the joke that all microbiome papers have their mechanism dependent on SCFAs. Or for metabolism, if you can't figure out the details, it will almost always be mTOR dependent.
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I love deep research. But I have to say I find it hilarious that an "outstandingly good" research report from Deep Research has one of the key insights that we should study gut microbiome dysbiosis and butyrate in chronic fatigue syndrome.
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Granted the UI for walkinlab is garbage in comparison, but I do like that it gives me full control of the specific tests I want. Also, some tests don't need to be taken longitudinally. E.g. Lp(a) only needs to be measured once in your life to understand it's impact on your CVD.
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I've used them to measure e.g. Lp(a), ApoB, and homocysteine. Couldn't get them covered by insurance.
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I really do think more people should be aware of walkinlab ( before wasting money on Function Health if they want to experiment with blood tests.
walkinlab.com
Order blood tests online with or without insurance or doctor visit. Walk-In Lab offers direct access to cheap blood work and lab testing with secure results.
@shelbynewsad If you don't want to go through your insurance you can just order specific tests for way cheaper at walkinlab:
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RT @magnificentgrnt: Check out the new 2024 Cohort of Magnificent Grants. And happy to report that going forward, the fellowship applicatio….
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Worth noting the dose they give mice here is 4g/kg ip. So completely different from your standard oral supplement which is like 1-3g total.
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This is a good take. I would also add that capturing value to create a venture-scale outcome from these tools will be far from trivial. As we have seen with all tools in biology.
One of the remarkable things for me about NeurIPS this year was how quickly the entire AI for Biology community has gone all-in on biological foundation models. Virtual cell models will enable us to predict how cell states will change in response to chemical perturbations.
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If you’re feeling really smart, you’re probably doomed.
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Gives a glimpse to a world where we could provide replacement cells and organs off-the-shelf without immunosuppression. That would be a remarkable world to live in. Looking forward to seeing the follow up at later time points.
In my 40 years of biotech, I was waiting to see this result. Never before have transplanted cells survived normal immune response without immunosuppression. Excited for patients, many whom I know see hope today for a possible cure for many diseases.
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