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Paolo Ciracì Profile
Paolo Ciracì

@p_ciracimd

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Medical Oncology Resident at the University Hospital of Pisa, Italy. Focused on clinical and translational research on gastrointestinal cancers.

Pisa
Joined December 2021
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@p_ciracimd
Paolo Ciracì
18 days
#ESMOGI25 was an incredible experience — truly honored to present results from the PARERE study by @FoundationGono in the Proffered Session
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@p_ciracimd
Paolo Ciracì
8 days
RT @myESMO: 📣 ESMO Living Guidelines on Metastatic Colorectal Cancer v1.3: Updated recommendations and algorithms for the treatment of pati….
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@p_ciracimd
Paolo Ciracì
8 days
RT @ACCMEDorg: YOUNG TO YOUNG @ ESMO GI 2025.. Le interviste "live" realizzate dagli inviati di Young to Young dura….
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@p_ciracimd
Paolo Ciracì
9 days
RT @Medi_Mix: 🎥 #ESMOGI2025 Highlight! Dr @PJCuyle discusses key advances in mCRC:.✔️ ctDNA surveillance increases curative-intent treatmen….
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@p_ciracimd
Paolo Ciracì
16 days
RT @myESMO: #ESMOGI25: Randomised #ClinicalTrials and real-world studies in #mCRC provide further evidence in favour of anti-EGFR rechallen….
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@p_ciracimd
Paolo Ciracì
16 days
RT @Larvol: Reactions on top trials during @myESMO Gastrointestinal (GI) Cancers Annual Congress 2025 curated by @Larvol CLIN. Explore mor….
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@p_ciracimd
Paolo Ciracì
18 days
RT @Larvol: Recap of Day 3 of ESMO - European Society for Medical Oncology Gastrointestinal (GI) Cancers Congress 2025: Top Trials. Explore….
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@p_ciracimd
Paolo Ciracì
19 days
RT @Erman_Akkus: 📢Proffered paper #ESMOGI25 @myESMO. ➡️PARERE trial, mCRC.➡️ctDNA guided anti-EGFR rechallenge.✅May detect new developed RA….
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@p_ciracimd
Paolo Ciracì
19 days
RT @martweetings: So proud of you @p_ciracimd 🤍
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@p_ciracimd
Paolo Ciracì
19 days
RT @MarioBalsaMD: 💥 Proffered paper #ESMOGI25 - PARERE trial: ctDNA-guided sequencing in RAS/BRAF wt mCRC. 💉Panitumumab re-treatment (vs re….
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@p_ciracimd
Paolo Ciracì
1 month
RT @Erman_Akkus: ⚖️Full publication of LEANOX Trial.@JCO_ASCO . ➡️Lean Body Mass–Based vs body-surface area Oxaliplatin Dose Calculation in….
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@p_ciracimd
Paolo Ciracì
1 month
RT @Erman_Akkus: 💉Liver-Directed Therapies in CRC.@ASCO Educational book . ✅HAI, ablation, TARE, SBRT, transplantation. 👉.
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@p_ciracimd
Paolo Ciracì
1 month
RT @Erman_Akkus: Are Early-Onset Cancers an Example of Accelerated Biological Aging? | Oncology | JAMA Oncology | JAMA Network https://t.co….
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jamanetwork.com
This Viewpoint describes accelerated biological aging as a potential mechanism by which exposures lead to early-onset cancers.
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@p_ciracimd
Paolo Ciracì
2 months
RT @CathyEngMD: @ChiaraCrem1 presenting PARERE phase 2 trial on the role of #ctDNA guided re-tx with PMab prolongs PFS #cancer #CancerResea….
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@p_ciracimd
Paolo Ciracì
2 months
RT @AIOMtweet: Un'intervista da #ASCO25 a Chiara Cremolini, dell'Unità di Oncologia Medica 2, AOU Pisana e Dipartimento di Ricerca Traslazi….
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@p_ciracimd
Paolo Ciracì
2 months
First results from the PARERE trial by @FoundationGono .🩸RAS and BRAF ctDNA muts: >1/3 of mCRC patients eligible for anti-EGFR re-treatment.➡️ pani re-tx was associated with higher ORR, DCR, and longer PFS independently of the treatment sequencing. @ChiaraCrem1 #ASCO25.@ASCO
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@p_ciracimd
Paolo Ciracì
2 months
Updated results from the phase 3 TRIPLETE study by @FoundationGono . ➡️ Upfront mFOLFOXIRI plus panitumumab resulted in a longer OS of 41.1 vs 33.3 mos (FOLFOX/pan) .➡️ no significant difference in PFS and ORR was confirmed . @VeroKonk #ASCO25 .@ASCO
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@p_ciracimd
Paolo Ciracì
2 months
DYNAMIC-III. 🩸27% ctDNA pos. ➡️ ctDNA is prognostic but not predictive for adjuvant chemo escalation. #ASCO25 @ASCO
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@p_ciracimd
Paolo Ciracì
2 months
Enco/cet + mFOLFOX6 is the new standard 1L for BRAF V600E mut mCRC patients.➡️ mPFS: 12.8 vs 7.1 mos .➡️ mOS: 30.3 vs 15.1 mos. #ASCO25 @ASCO
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@p_ciracimd
Paolo Ciracì
3 months
RT @AndreaCercek: Congratulations to our team. Next chapter in Nonoperative Management of Mismatch Repair–Deficient Tumors | New England Jo….
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nejm.org
Among patients with mismatch repair–deficient (dMMR), locally advanced rectal cancer, neoadjuvant checkpoint blockade eliminated the need for surgery in a high proportion of patients. Whether this ...
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