It feels a little surreal but my first paper is finally published! with amazing collaborators from across @UniofBath, @UKHSA and Tokyo University of Agriculture and Technology, we investigated cationic biocide tolerance in Proteus mirabilis (1/11) 🧵.

RT @ShaniUPAli: Had a great time at #CHRO2024 !Grateful to be able to present on campy aerotolerance alongside great talks from @Benizao an….

RT @PinkPetri: There is a major lack of microbial/music parody stickers. Thankfully I'm here to change that! . http….

RT @Ellijos: Excited to share my 1st paper along with @drbridgetwatson @TaylorLabGroup @edzewestra Sylvain Gandon and David McLeod https://….

RT @isobelmicro: A fantastic end to #Microbio24. Thanks so much @MicrobioSoc for giving me the chance to speak about my work on polymicrobi….

RT @flanagella: If anyone wants to talk about convergent regulatory evolution in Pseudomonas, come talk to me at my poster this afternoon a….

RT @AnthonyJSlate: Hi Microsoc people!. If you're interested in how bacteria can produce electricity (microbial fuel cells) and its potenti….

RT @ShaniUPAli: Thank you to @MicrobioSoc for letting me present a flash talk on my PhD work. If five minutes of me talking about campy evo….

RT @ChandlerMBray: Not enough gets publicised about how hormone dependent cancers will obviously have a skewed impact on trans people under….

RT @AnthonyJSlate: The primary findings from my PDRA role have just been published! Thanks to collaborators from @….

RT @apreston243: @KeiraCozens wrapping up the morning AMR session at #microbio23. @MicrobioSoc @LifeScienceBath @EpicFeil_ .

RT @kelly_beanzzz: Fantastic opportunity to talk about our outreach event at #Microbio23! Come and chat at poster 423 this evening if you w….

RT @flanagella: Equal parts excited and terrified to be doing a talk at #microbio23 today! Do come along to hall 9 at 12:15 if you're even….

RT @A_Kazubska: First conference of my PhD #microbio23 #microbiologysociety #hydrogelcoatings #cautis

RT @AnthonyJSlate: Great first day at #microbio23! If anyone is interested in the development of an infection responsive urinary catheter c….

RT @Ellijos: For one day and one day only, come and see my poster (p322) at #microbio23 to hear about whether slapping CRISPR-cas systems i….

I’m presenting my work on the role of LPS structure in biocide tolerance and crystalline biofilm formation in CAUTI pathogen Proteus mirabilis at #microbio23 today in the form of a rather unhinged poster - p055 come along for a chat! 🧫🧫

…Lucy Bock, Matthew Wand, Kazunori Ikebukuro, @GebhardLab, Mark Sutton and of course Brian Jones for contributing to this manuscript! A little shameless self promotion but I’ll be presenting a poster at #microbio23 P055 if anyone would like to chat about the data 🧫🔬.

A massive thank you to the co-authors of this paper from @LifeScienceBath, @HealthcareUKHSA and TuAT, @Harriet_Pelling, @Moochioooooo, Takanori Matsumoto, @GraceGregory_ Jonathan Nzakizwanayo, @AnthonyJSlate, @apreston243, Maisem Laabei… (10/11).

In summary, we concluded that SmvA-mediated efflux appears to work in synergy with LPS mediated exclusion of biocides, to modulate overall susceptibility in P. mirabilis, and that virulence factors such as crystalline biofilm formation are also affected by LPS structure (9/11).

Finally, we assayed RS47 and its derivatives against a panel antibiotics and cationic biocides. Interestingly, LPS structure and SmvA efflux were found to impact susceptibility to all biocides assayed, but did not affect antibiotic susceptibility (8/11)