Murtolalab
@murtolalab
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We are a research team that explores lipid- and cholesterol metabolism in prostate cancer and clinical value of lipid-targeted interventions
Tampere, Finland
Joined February 2023
RT @EurUrolOpen: PCa: Elevated Levels of Serum Thymidine Kinase 1 Predict Poor Survival for Patients with Metastatic Prostate Cancer by @Tm….
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In localized #prostatecancer Ki-67 tumor proliferation marker and PSA decrease as tissue concentration of atorvastatin lactone goes up. Lipid-based 3LS score on prostate tissue correlates with Gleason grade, but is not prognostic. Our latest publication:.
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RT @VickersBiostats: There is no statistical solution to the problem of causal inference from observational data, it requires good scientif….
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RT @VickersBiostats: "If you are going to write a scientific paper for publication, you are also going to have to write a response to revie….
europeanurology.com
Peer review and comments from reviewers are part of the submission process for scientific papers. We provide tips on how best to respond to reviewers, and point out the most common mistakes that...
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PhD student Kalle Välitalo enjoying himself at #METresearchday while presenting our results on lipidomic changes in #prostatecancer cells under hypoxia. Research can be fun! @TampereUniMET
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We are very grateful to the Finnish Cancer Foundation for important and continued support for the ongoing #ESTO2 clinical trial! @Syopasaatio.
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Our latest publication demonstrates independent prognostic role of serum thymidine kinase 1 in metastatic #prostatecancer This biomarker improved accuracy of predicting survival both in hormone-sensitive and castration-resistant disease @EurUrolOpen.
pubmed.ncbi.nlm.nih.gov
We found that for patients with metastatic prostate cancer, high levels of a protein called TK1 that is involved in cell division was linked to higher risk of death. Our findings need to be confirmed...
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A collaboration study with @NykterLab highlighting importance of club-like cells in the interaction between #prostatecancer and the immune system has been published.
pubmed.ncbi.nlm.nih.gov
Prostate cancer treatment resistance is a significant challenge facing the field. Genomic and transcriptomic profiling have partially elucidated the mechanisms through which cancer cells escape...
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Robot-assisted versus three-dimensional laparoscopic radical prostatectomy: 12-month outcomes of a randomised contr…
pubmed.ncbi.nlm.nih.gov
We were unable to demonstrate a difference between the RALP and 3D-LRP groups for functional and oncological outcomes at 12 months after surgery.
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Our randomized trial comparing 3D-assisted and robot-assisted techniques in laparoscopic radical #prostatectomy for #prostatecancer has won the best publication award of the Finnish Urological Association .
pubmed.ncbi.nlm.nih.gov
We were unable to demonstrate a difference between the RALP and 3D-LRP groups for functional and oncological outcomes at 12 months after surgery.
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RT @auvinen_anssi: Annual retreat of the Tampere Prostate Cancer Research Center: Excellent talks in pleasant surroundings with brilliant p….
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RT @CoEinTG: Cell line models of prostate cancer can help us understand how tumors become resistant to treatment. Doctoral student, Reetta….
tumorgenetics.blog
This article explores the treatment resistance of prostate cancer, the most prevalent cancer among men. It highlights the mechanisms behind androgen receptor activity that complicate therapy. Resea…
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RT @APCCC_Lugano: Radical Prostatectomy Versus Stereotactic Radiotherapy for Clinically Localised Prostate Cancer: Results of the PACE-A Ra….
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Dr. Roni Joentausta defended succesfully his PhD thesis on statins, metformin and prostate cancer survival and risk of erectile dysfunction after radical prostatectomy. Opponent was professor Timo Strandberg, @Tmurtola served as kustos. Congratulations to Roni!
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Tutkimusryhmämme jäsen Roni Joentausta väittelee Tampereella 30.8 koöesterolilääke statiinien ja diabeteslääkkeiden käytön yhteydestä eturauhassyövän ennusteeseen. Tulokset herättävät mediahuomiota:.
hs.fi
Kolesterolia alentavilla statiineilla ja diabeteslääke metformiinilla oli suomalaistutkimuksessa yhteys alempaan syöpäkuolleisuuteen.
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Keep up the good work @andreasroder1 @schloeffeler @OttoEttala @TimoMarttila @HSeikkula @andreskotsar @AinoSiltari @IlkkaJussi41079 @UrologicalRunit @SykehusVestfold and many others who make this happen!Thank you for support to @Syopasaatio @SuomenAkatemia and Nordic Cancer Union.
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We are happy to report that #ESTO2, our first-ever phase 3 RCT on efficacy of atorvastatin in combination with ADT against advanced #prostatecancer has now recruited over 200 patients, surpassing 50% of the recruitment target. Recruitment speed currently approx 7 patients/month.
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RT @urotoday: Cancer origin tracing and timing in two high-risk prostate cancers using multisample whole genome analysis: prospects for per….
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