MS Lee Lab
@msleemslab
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A research group interested in proteomics, peptidomics, and PTMomics in neuro-diseases📍@TU_Muenchen | CLINSPECT-M consortium | opinions are my own (Chien-Yun)
Germany
Joined September 2018
Kicking off the new year strong! 🚀 Prosit-Cit is officially online on MCP! Check it out: https://t.co/zfy8FCWN1A Follow us on Bluesky for more exciting research updates! @
mcponline.org
In BriefWe developed a specialized deep learning model to predict MS2 spectra of citrullinated peptides, improving sensitivity and precision in citrullination site identification by up to 14 times in...
New preprint from us is out! 🍻 We developed a deep learning model to predict MS2 spectra of citrullinated peptides, improving site ID by up to 14x in human tissue proteomes with high precision! Read more: https://t.co/2jvxvfVB7A
#DeepLearning #Citrullination #Bioinformatics
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💥A week full of top notch science & a lot of fun with scientist from all over the world has come to an end at #HUPOEuPA2024. Many thanks to @hupo_org @EuPAProteomics @EU_YPIC & #DGMS🧵 (1/4)
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We had a fantastic time at #HUPO2024, it was a blast! Thanks #HUPO and #Dresden! 👏#TeamProteomics #TTTT
That's a wrap on #HUPO2024! Kusterlab, Leelab, Wilhelmlab, and BayBioMS had an awesome time in Dresden. It was good to meet so many familiar and new faces in the community. See you next time!
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Come and visit us!
#HUPO2024 starts tomorrow and the Terrific TUM Team is ready! Kusterlab, Wilhelmlab (@wilhelm_compms), Leelab (@msleemslab) and BayBioMS (@BayBioMS) have printed their posters and prepared their talks, and we're very excited for the next days. See you in Dresden!
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This is a project collaborating with Mathias @wilhelm_compms and Wassim @wassimbahaa, and the pipeline is now available through Oktoberfest! 🍻 Can't wait to try it? GitHub:
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New preprint from us is out! 🍻 We developed a deep learning model to predict MS2 spectra of citrullinated peptides, improving site ID by up to 14x in human tissue proteomes with high precision! Read more: https://t.co/2jvxvfVB7A
#DeepLearning #Citrullination #Bioinformatics
biorxiv.org
Citrullination is a critical yet understudied post-translational modification (PTM) implicated in various biological processes. Exploring its role in health and disease requires a comprehensive...
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Thrilled with #Embocitrullnation success @MAChristoLab thank you all the participants 🤗 Grand merci @IpbsToulouse @IsabelleSaves1 @ToulouseCancer
@GillesFavrecrct
That's already the end of this great @EMBOevents #EMBOcitrullination Last session to award prizes of the best short talk and poster presentations, granted by the Fondation @ToulouseCancer in the presence of its director Prof. Gilles Favre
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Wonderful #EMBOcitrullination workshop with #citrullination experts in Toulouse! We enjoyed all the stimulating discussions! Thrilled by the community's recognition of our research! 🤩Thanks @psharmalab @MAChristoLab @IpbsToulouse and amazing people who make it happen! 👏
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Final Day of #ASMS2024 in Anaheim, but the Terrific TUM Team is far from done! Ludwig from Wilhelmlab will tell you all about Koina today. And at their posters, meet Flo (Kusterlab), Joel (Wilhelmlab), and Miri (@BayBioMS). See you there! One final time: Go #TeamMassSpec!
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It's Wednesday at #ASMS2024 and we are going #kusterscale! In the morning, you can check out the talks of Nicola and Rebecca (from @msleemslab), in the afternoon Yun and Cecilia will show you their latest results. All day, you can visit the posters of Johanna and Armin. See you!
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If you’re interested in endogenous peptides and proteolysis in the plasma, come and talk to Andreas! #peptidome #proteolysis #ASMS2024
Here's to another day of exciting posters and talks at #ASMS2024! Kusterlab and @msleemslab are looking forward to meeting you!
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Here's to another day of exciting posters and talks at #ASMS2024! Kusterlab and @msleemslab are looking forward to meeting you!
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Excited to announce that our team will be at #ASMS2024 with 1 talk and 1 poster! We're eager to connect with fellow #citrullination and clinical #peptidome enthusiasts. See you there! 🎉
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Together with Kusterlab @kusterlab and Wilhelmlab @wilhelm_compms we are happy to join #ASMS2024 and looking forward to many awesome discussions! 🤩#TeamMassSpec #TerrificTUMTeam
What's up Anaheim! The Terrific TUM Team, aka Kusterlab, Wilhelmlab, and Leelab, is excited for #ASMS2024. Here is our program for the next few days. We hope to meet many of you there and are excited to check out all of your presentations! Let's go #TeamMassSpec
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...dose-resolved proteomics (acetylome, phosphoproteome, and full proteome), revealing key insights into drug MoA and enzyme substrate relationships. Explore our dataset on ProteomicsDB 🖥️ Read the full paper here 📖:
cell.com
Chang et al. systematically measured the dose-dependent response of cancer cells to 21 KDAC inhibitors at the proteome, acetylome, and phosphoproteome levels. The data can be explored in ProteomicsDB...
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Decrypting the molecular basis of cellular drug phenotypes by dose-resolved expression proteomics https://t.co/avBogXefdK
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Happy to be part of #DGMS 2024! This afternoon we will be presenting at P104 about our peptidomic workflow revealing thousands of endogenous peptides from plasma samples!
Welcome to Freising! The Terrific TUM Team is proud to be one of the hosts of this year's DGMS conference.🤩 We are looking forward to four days of presentations, discussions, and networking. Of course, our labs also have a lot to offer. Check out our schedule below!😎 #DGMS2024
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Humbled to share #upcoming @EMBO workshop on emerging era on #citrullination , July 8–11, 2024 #Toulouse Grateful for amazing colleagues & co-organizers @IsabelleSaves1 & Françoise Viala @IpbsToulouse
@MAChristoLab M.Simon @InfinityTLS Website COMING Please RT #EMBOCit2024
📢Upcoming: EMBO Workshop on protein #citrullination 📢 July 8-11, 2024 Toulouse, France We will have talks from all facets of citrullination research, several slots for presentations from abstracts and fantastic social events. #EMBOCit2024 🚀🚀
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📢Upcoming: EMBO Workshop on protein #citrullination 📢 July 8-11, 2024 Toulouse, France We will have talks from all facets of citrullination research, several slots for presentations from abstracts and fantastic social events. #EMBOCit2024 🚀🚀
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Worried about how to use it? Beyond the examples in our paper, a wealth of information awaits your exploration on ProteomicsDB: https://t.co/duutgcHNK8 Last but not least, huge thanks to all the coauthors and a special shoutout to @kusterlab the terrific support! #sarcoma
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