MultipleSclerosis_CME
@ms_cme
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Your only source for joint-accredited, social media-based, serialized education on multiple sclerosis. CME/CE credit for physicians, nurses, and pharmacists.
Joined May 2021
You have found it! Your new source for free CE/CME by Twitter! Each program provides 0.5h credit for physicians, pharmacists, and nurses. Launching soon! Accredited by @academiccme
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Great opportunity for leading-edge CE/#CME! Don't miss it--in #Phoenix for #CMSC25 or virtual! @academiccme
Register TODAY for a live and virtual CME/CE course: An Update on Multiple Sclerosis Patient Care for Advanced Practice Providers on Tues. May 27th from 4:00 pm - 6:00 pm MST, just before #CMSC 2025. Join Amy Perrin Ross, APN, MSN, CNRN, MSCN and esteemed faculty panel for this
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25) And that's it! Please go to https://t.co/8Gxt7qnInq and claim 0.5hr π CE/#CME credit. You can also learn much more from our 2024 Advanced Curriculum course at https://t.co/MOn7MxoZq7.
academiccme.com
2a) Feel free to send more ββ to @ms_cme by DM anytime! This CE/#CME accredited program was supported by independent educational grants from Bristol Myers Squibb; EMD Serono; Mylan Specialty L.P., a...
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24f) In sum, then, monitoring #NfL levels alongside #MRI findings, including #gadolinium-enhancing lesions, can provide complementary information about disease activity and treatment response in #MS.
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24d) In this study, unlike #GFAP, #tau protein, #UCH_L1, #S100B, & #MMP9, only higher #NfL values in #CSF or blood indicated #gadolinium enhancement (OR 1.05; 95% CI 1.0β1.09) & correlated w/number (Οβ=β0.47; pβ<β0.001) & diameter of enhancing lesions (Οβ=β0.58; pβ<β0.001).
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24c) Therefore there's interest in whether serum biomarkers such as #NfL may be valuable as surrogate parameters to evaluate #MS activity. This was evaluated in the #REDUCE_GAD study, π
onlinelibrary.wiley.com
Background The presence of contrast enhancement (CE) on magnetic resonance imaging (MRI) is one of the principal criteria for diagnosis and disease activity of multiple sclerosis (MS). Therefore,...
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24b) The presence of #gadolinium enhancement on #MRI is one of the principal criteria for dx and assessing disease activity of #MS. Therefore, #pwMS patients are frequently exposed to contrast agents, which may cause deposition in the brain, restricting its use in repeat exams.
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24a) One last β: Does neurofilament light chain (NfL) as a biomarker correlate with gadolinium enhancing lesions? Keep in mind important facts pointed out in π
onlinelibrary.wiley.com
Background The presence of contrast enhancement (CE) on magnetic resonance imaging (MRI) is one of the principal criteria for diagnosis and disease activity of multiple sclerosis (MS). Therefore,...
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22b) Utility: #VEP is particularly sensitive in detecting subclinical #optic_nerve dysfunction, meaning it can identify changes in the optic nerve even before clinical symptoms manifest or when symptoms are subtle.
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22a) Visual evoked potentials #VEPs are the expression of electrical activity in the visual pathways up the optic nerves and to the calcarine cortex. VEP can detect delays or abnormalities in the transmission of visual information from the eye to the brain.
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21b) Utility: #OCT is valuable in assessing structural changes in the optic nerve & retina. It can detect thinning of the #RNFL, which is indicative of #optic_nerve damage or degeneration.
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19) OK, next query: Between #VEP and #OCT, is one more effective in diagnosing #optic_neuritis or are they typically both ordered for confirmation? Great question! Check out π https://t.co/ZdVKrNYg4w and π
pmc.ncbi.nlm.nih.gov
Optic neuritis (ON) is a debilitating condition thatΒ through various mechanisms, including inflammation or demyelination of the optic nerve, can result in partial or total permanent vision loss if...
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18) KNOW your #MS clinical pharmacist! These are some of the paths along which they may train (π https://t.co/YiIb8v3kyB):
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