New @BioMedCentral paper presents first evidence-based regimens of single low dose primaquine SLDPQ, offering flexible options for malaria elimination. The case for 3.75 mg is compelling @WHO needs to urgently consider reinstating it. Here's why:

A sharp decline in piperaquine-resistant P. Falciparum #malaria following drug policy revisions across the Greater Mekong Subregion highlights how real-time genetic data can support timely, evidence-based responses to shifting malaria threats @NatureComms .

Antimicrobial Resistance (AMR) disproportionately harms disadvantaged, marginalized populations, yet #AMR research often excludes their experiences, data & voices in leading to skewed priorities & blind spots in research. What drives this injustice? .

P. vivax malaria cases numbers have rebounded in the last 2 yrs, putting at risk malaria control and elimination. Why is evidence for high-dose primaquine for P vivax relapse so clear, especially for regions proceeding towards malaria elimination?.

Understanding contextual factors is critical to the success of health service planning & implementation. However, few contextual data are available at village level in rural South and SE Asia. What gaps were found in 7 sites in Thailand, Cambodia, Laos, Myanmar & Bangladesh?

How to ensure safer, more effective drug treatments for pregnant or lactating women & children? . Physiologically-based pharmacokinetic (PBPK) modelling simulates how drugs behave in the body & adjusts doses based on physiological changes. @radboudumc.

REGARD-VAP trial @InfectiousMoYin: Reducing antibiotic duration key to antimicrobial stewardship. Review of 315 trials found strong evidence for shorter courses in common infections but limited data for severe infections & low-income settings.

What triggers Plasmodium vivax parasites hypnozoites activation? Our simple within-host mathematical model of P. vivax hypnozoite activation provides evidence that symptomatic falciparum #malaria can trigger hypnozoite activation.

Rapid spread of artemisinin partial resistance (ART-R) #malaria across east #Africa, Horn of Africa & southern Africa threatens malaria control, puts millions of lives at risk, may reverse decades of progress .What can we do NOW to address ART-R in Africa?

RT @xhschan: 🕊️ 🌍 🌎 🌏 ⚕️🕊️ .It's #OxTropMed24 this Friday at Lecture Theatre 2 at the John Radcliffe Hospital in Oxford and online via Team….

Attn #malaria researchers. Register today! @ASCPTjournals panel 1:30-2:30 ET (USA) Wed 4 Dec

Congratulations to @Joel_Tarning, just named Distinguished International Fellow at #astmh2024. Joel was recognized for "his exceptional scholarly accomplishments [&] global leadership antimalarial pharmacology." Well done, Joel!.

New insights into #dengue! In-host dengue kinetic model quantitatively predicts dengue fever drug effects, offers valuable insights to inform dengue drug development and shows that #Ivermectin reduces NS1 but not viral load.Learn more! Photo @LukeDuggleby

RT @rjmaude: I am leading a new Border Malaria Interest Group for @APMEN to document activities, share experience and promote action across….

RT @IDDOnews: Our Medicine Quality Monitoring Globe is an online tool mapping reports of #SubstandardMedicines and #FalsifiedMedicines from….

Attn @WHO @UN C-reactive protein CRP testing in primary care can rule out using antibiotics in respiratory infections TO FIGHT #AMR We can't wait for superior tests. Donors & policymakers: Step up NOW w financing & training for CRP testing in primary care!.

RT @OUCRU_Programme: It's a wrap! The first #MODRA workshop was a success! 🎉 Can't wait to welcome participants to Vietnam for the 2nd work….

RT @TropMedOxford: Research Highlight from Bob Taylor @MORUBKK. Prevalence and associated risk factors of #stunting, #wasting/thinness, and….

What are the challenges to & opportunities in expanding #malaria post (MP) roles so that MPs can provide community-based health services beyond malaria - maybe for dengue, diabetes, insect bites, diarrhea, mental illness & substance abuse - in the Greater Mekong Subregion #GMS?

RT @Oxford_GRAM: GRAM time series shows 1m annual deaths due to AMR since 1990, & sharp rises coming. DRIs to claim 39m lives by 2050 .-sto….