Michael Koeris
@mkoeris
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Director of the Biological Technologies Office @DARPA. BOD @addgene. Serial founder Vulcan Biologics, GDMC, Sample6 (acq.), Corvium (acq.); frm. Prof @KeckGrad!
Arlington, VA
Joined February 2009
This is a terrific analysis on ‘why data centers in space’. And the results are believable. As I wrote earlier, Elon can maybe get this done, but it won’t be easy. https://t.co/YXxXuSzrLJ
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When you change the way you look at things, the things you look at change. - Max Planck (1858 - 1947)
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"Ben Zobrist and Jon Lester are on the ballot this year ... there's a good chance that one or both of those guys will be on and in." @MLBBruceLevine previews the 2026 Cubs Hall of Fame ballot on Cubs 360 👀
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At Edison Scientific, we build agents for scientific discovery. Training these agents often requires scaling to 1000s of simultaneous environments, for which we rely on @nvidia's recently announced NeMo Gym and RL frameworks. Read more about the integration with Aviary
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2026 will be a year of scientific acceleration through AI. just released a benchmark to measure the capability of AI on expert-level scientific reasoning:
We’re releasing a new eval to measure expert-level scientific reasoning: FrontierScience. This benchmark measures PhD-level scientific reasoning across physics, chemistry, and biology. It contains hard, expert-written questions (both olympiad-style problems and longer
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Our answer to the ever changing conditions of combat. Delivering care to our warfighters to keep US combat power at the peak! 🫡🇺🇸
Pain management is crucial for injured warfighter comfort and recovery. Our Live Chain effort is investing in novel anesthetics that are safe, effective, and easy to administer by non-experts. Learn more: https://t.co/eEXWQbmpnP
#MilitaryMedicine #Innovation #CombatMedics
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Pain management is crucial for injured warfighter comfort and recovery. Our Live Chain effort is investing in novel anesthetics that are safe, effective, and easy to administer by non-experts. Learn more: https://t.co/eEXWQbmpnP
#MilitaryMedicine #Innovation #CombatMedics
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.@USWREMichael wants to help create new primes within the defense industry: "My job is to create five more companies that work [with] the Department and bring new capabilities."
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🚀Episode #3 of The Upside is live! Pancreatic cancer remains one of the hardest, deadliest cancers to treat. But $ACTU’s lead drug has shown meaningful improvements in survival – and could be the start of a true “pipeline in a molecule.” With major regulatory + clinical
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"...we’re not just editing genes anymore we’re creating a bidirectional communication protocol between silicon & carbon where light becomes the universal language..."
I believe DARPA just launched the most audacious bioengineering program of the decade & nobody’s talking about it loud enough I spent hours reading through the Generative Optogenetics program documentation & honestly I’m still processing the implications of what they’re trying
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pretty insane (insane = good) ultra biotech acceleration DARPA is working on something called “generative optogenetics.” The basic idea is to use flashes of light to write DNA or RNA directly inside living cells, instead of doing the usual slow cycle of synthesizing DNA in
There's a new DARPA program on "Generative Optogenetics." The goal is to write DNA or RNA directly in cells using flashes of light, rather than building it in tubes, transforming/growing cells, and so on. If it works, it could speed up molecular biology experiments. Cloning
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.@USWREMichael speaks on the @DeptofWar’s six Critical Technology Areas: - Applied AI - Biomanufacturing - Contested Logistics Technologies - Quantum - Battlefield Information Dominance - Scaled Hypersonics - Scaled Directed Energy
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This was a joint crank between @OpenAI, @RedQueenBio and Robot on Rails. 🫡 to Nikolai Eroshenko, @MilesKWang, Rachel Smith, @omnivorous_egg, @tejalpatwardhan, @kemobsj, Chase Olle, @AzadehSamadian and Nitin Mahadeo.
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Also thanks to @axios for covering the story!
axios.com
Early evidence shows that AI can improve real-world laboratory workflows.
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Full @OpenAI blog link, with a lot more detail:
openai.com
GPT-5 created novel wet lab protocol improvements, optimizing the efficiency of a molecular cloning protocol by 79x.
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And of course, at @RedQueenBio, we're building similar lab-in-the-loop workflows to co-scale defensive biological capabilities as the models improve.
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Web2 companies, content creators, sports leagues, gaming teams... They'll all shift towards implementing NFTs and other Web3 elements within their existing businesses and communities. Not just to create a PFP collection for a quick profit, but to actually take advantage of this
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Then there's biosecurity. We built this eval as a leading indicator for riskier model capabilities. Bio red-teaming has focused on zero-shot designs. The fact GPT-5 can reason over multiple experiments means taking lab interaction into account for risk assessment, similar to how
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It's cool but still early! This was not a foundational breakthrough in molecular biology, and needed humans to execute. But it does feel like a signal of where AI science might go. If all AI ever does is optimize workhorse protocols like this, that's still a big boost.
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The robot generated similar quality data to human scientists but got lower absolute performance metrics. So there is still plenty of room for improvement to improve precision and capture nuances of manual lab work.
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With Robot on Rails, we built a robot that takes a cloning protocol described in English and executes it in the wet lab. This combined a human-to-robot LLM translator, a vision system and a path planner. The goal here was to increase throughput for more scaleable future evals.
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The Relentless War on Masculinity by @DavidMaywald is the guide book on advocating for men and boys—proudly and effectively, driven by principles and with respect for others. It is also a manual for rebuilding healthier societies, with stronger relationships between men and
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