Chronic activation of the stress response increases allostatic load, which impairs memory, learning, and executive function over time. Managing load is a prerequisite for consistent performance.

Consistency outperforms intensity when neural recovery is prioritized. That’s not opinion. That’s systems biology

The brain experiences relief when behavior aligns with long-term goals. That’s dopamine working after consistency, not before it.

Your physiology doesn’t know what “vacation” is. It only knows whether signals continue or disappear.

You don’t lose fitness overnight. You lose it by letting disruption turn into abandonment.

Protein isn’t about optimization. It’s about preserving lean mass, satiety, and metabolic stability during disruption.

New Episode! "190. Holiday Travel Protocol, Protein Debates, & Planning to Fail" Darsh and Altamash break down why health outcomes are shaped by small, repeated choices (not occasional slip-ups). Us… Player links & show notes:

One of the most studied supplements in history still gets labeled as “unsafe.” Meanwhile, the evidence consistently shows creatine is safe and effective at standard doses.

Creatine after 40 = longevity cheat code. You lose muscle faster with age, and creatine literally slows that process down by boosting strength, recovery, and muscle protein synthesis.

When a supplement can improve function in areas like major depression, TBI, and bone density, it moves past "performance" and becomes clinical medicine. This is the shift we are seeing.

Did you know Creatine is being studied as an open-label adjunctive treatment for female adolescents with SSRI-resistant major depressive disorder? The brain health conversation is evolving fast.

Creatine induces changes in cerebral high-energy phosphates during sleep deprivation. Translation: It directly fuels your brain cells to perform better when you're exhausted.

New Episode! "189. Creatine as Medicine: Brain Health, Bone, & Longevity | Darren Candow, PhD" Join Dr. Altamash Raja and Dr. Darsh Shah on Medicine Redefined as they introduce Dr. Darren Candow, a … Player links & show notes:

Metabolic health influences tendon recovery. Insulin resistance and inflammation slow repair and increase irritability.

Hip pain isn’t just structure. It’s the interaction of morphology, load, tissue capacity, and neuromuscular control

FAI syndrome is clinical. Pain depends on movement patterns and load tolerance—not bone shape alone.

Imaging findings don’t predict symptoms. Functional testing explains pain far better than MRI.

Long-term hip preservation comes from integrating structure, control, load management, and metabolic health—not imaging alone.

You don’t need to ‘realign’ anything — you need strength, load tolerance, and less fear.

Your pelvis is unstable’ = the musculoskeletal version of ‘Mercury is in retrograde