Explore the diagnostic algorithm for the metabolic/kidney stone disease- Primary Hyperoxaluria (PH) for the 3 known types of PH with a case report describing kidney failure in a relatively young PH3 patient.

A man's life must be nailed to a cross either of Thought or Action. ~ Sir Winston Churchill

Fed decision not to cut rates is a myopic decision. I am no expert by any means on economic matter but a common sense based observation shows that inflation is cooling and other nations are already cutting interest rates including European Central Bank. Someone of the stature of.

"Thirty-one percent of physicians said prior authorizations are often or always denied.". From a personal standpoint, stat 5 has been my experience as well. If there is an easier way by which physician determined treatment plan is allowed to continue even as payers (health.

In order to decrease physician shortage, another approach would be to have an expedited pathway for thousands of qualified and perhaps overqualified MDs physicians (IMGs) who would be more than willing to provide high quality care to seniors in US if they are allowed a pathway.

One way to mitigate physician shortage in rural areas of US and perhaps inner city urban centers would be to increase reimbursements for physicians who are in primary care/prevention medicine including physicians who care for chronic conditions such as diabetes, heart failure and.

How about shifting the reliance on medicare funding for GME (residency/fellowship) to private inititiaves such as hospital funded programs- after all its the hospitals who rely on residents talents and hard work to provide care to patients- is it too much to ask hospitals to foot.

. How is hospital care affected?. Hospitals are feeling the effects of GLP-1 uptake, and widespread weight loss could affect hospital strategy and operations downstream. The medicines are leading to magnified weight loss programs, more transplants, a.

Mankind is always trying to slow the aging process and delay the inevitable which is death but is metformin one such agent that can help us do that? My view is : likely not. On the other hand, the day is not far when Metform will likely be dethroned as the first agent in the.

Should Metformin remain as the first line agent for oral treatment of T2DM? . NYTimes piece sheds some light on how Metformin is being used and to a certain extent touted as an anti-aging agent? The journal itself does not endorse the view.

For a paradigm change: US physician reimbursement model is geared towards wRVU model- physicians who do procedures are heavily rewarded in terms of their Work Relative Value Unit - wRVU thereby naturally causing a shift among medical students and residents to lean towards those.

Agree with the WSJ authors who are also physicians at Yale School of Medicine:. "To make this revolution a reality, the U.S. needs a comprehensive national initiative to map, model and mitigate postinfection syndromes as well as tackle chronic diseases by addressing their.

1. More torsemide was recovered in the urine then furosemide suggesting higher bioavailability of furosemide. 2. Natriuresis (salt excretion) was substantially greater in the torsemide group (FENa) 4.1%63.5% versus 2.5%62.4%, P , 0.001) .3. There was a greater neurohormonal

So in heart failure patients, which diuretic will be better? . Furosemide or Torsemide . Results of study led by Dr Testani from Yale med school was recently published in Journal of American Society of nephrology. This was a multicenter, prospective, observational mechanistic

Watch out for Eli Lilly's Orforglipron- though the official trial data needs to be seen, based on early reports and as described in NYTimes piece- orforglipron appears to have the potential to lead in the class of GLP-1/dual GLP-1/GIP agonists. A daily pill may be as effective.

Do we need another pharmacologic agent for treatment of lupus nephritis?.Kidneys may be affected in up to 60% of cases of lupus. About 1/3rd of such patients may end up with kidney failure. American College of Rheumatology recommends triple therapy for lupus nephritis

Does the kidney transplant system need to change?. Even with over 48000 organ transplant happening in 2024 with over 50% of them being kidney transplant, 17 people die each day waiting for an organ transplant. There are currently over 103,000 people on national transplant

From @DrJBhattacharya .

The biotech scorecard for the second quarter: 24 stock-moving events to watch . Vera Therapeutics: Top-line results from the atacicept Phase 3 ORIGIN trial in IgA nephropathy. Prothena: All-cause mortality results from the birtamimab Phase 3 AFFIRM-AL study in AL amyloidosis.