mandeep singh
@mandeep_mayo
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Professor of Cardiology @MayoClinic; Interventional cardiologist with passion for aging research. Proud dad and husband. All opinions my own.
Rochester, MN
Joined January 2020
Key teaching points when you switch P2Y12i.Acute<30 d: Always bolus. Don't wait if you escalate from clopidogrel. For de-escalation: wait 24h.Chronic >30d: Wait 24h. Give maintenance dose except when switching from ticagrelor to prasugrel/clopidogrel (give bolus)
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Antiplatelet & Anticoagulation Rx.2025 ACC/AHA ACS Recommendations
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Remember 365 for prolonged DAPT Tradeoff.For every additional year of DAPT/1000 patients Rx.You save 3 stent thrombosis, 6 MI but add 5 major bleeds. It roughly translates into 1% decrease in ischemic & 1% increase in bleeding risk. Always calculate the ischemic/bleeding risks.
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RT @maor_elad: A true nightmare in the cath lab: 50M with inferior STEMI, normal coronaries, then collapsed. Aortogram clip speaks for itse….
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Dasatinib with Quercetin (D & Q) combination is a powerful senolytic shown to be beneficial in IPF, osteoarthritis in animal studies. Here are some food groups that one should consider in diet: surprising winners are onions & capers. Strawberries are rich in Facetin, a senolytic.
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1/2: One of the major anti-aging advances have been the development of senolytics; compounds that remove senescent cells and their harmful effects.
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All you need to know about iatrogenic coronary perforations.
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No one wants to relive this nightmare! . What are the possible reasons for this outcome?
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Pledge not to intervene before giving IC NTG. This patient had MINOCA, an important etiology of AMI, especially in the young.
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55YM presented with anterolateral STEMI. H/O prediabetes, hypertension and hyperlipidemia. Troponin 5,573ng/L. How would you approach the lesion in the LAD?
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5 “H”s to be a good “Human” being . 1: Humble, Be.2: Honest, Be.3: Humane, Be.4: Humility, Show.5: Humanity , Serve.
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You can calculate PCI risk in the EMR before patient goes for angiography. Four in-hospital adverse events (death, stroke, bleed, AKI) following PCI predicted with excellent discrimination from a few pre-procedural variables.
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We are so close! . PCI Risk calculations can be done automatically with EMR. Automated Real-Time Percutaneous Coronary Intervention Risk Model Leve.
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Hemodynamic Series 12.How would PA pressures differentiate Group 2 (secondary to left heart disease) from Group 3 (lung disease) pulmonary hypertension?
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Three interventions that you can do in cath lab to bring out hemodynamic significance of a stenotic lesion.
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Not all gradients are created equal. Helpful tips towards recognition of HCM.
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Always confirm Pulmonary Capillary Wedge Pressure with Oxygen Saturation.
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Everything you need to know about apex beat. Answer to yesterday's trivia.
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Trivia.Clinical examination can provide a wealth of information. Here are 5 frequently-encountered patterns of apex beat.
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