Enhancer/loops paper @loops_enhancers X Profile

Enhancer/loops paper

@loops_enhancers

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#chromatin, #enhancers and #genome_architecture @IvKrivega

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Enhancer/loops paper

@loops_enhancers

5 years

Last day for this account. Please follow @EnhancerLoop .

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Enhancer/loops paper

@loops_enhancers

5 years

Rapid Enhancer Remodeling and Transcription Factor Repurposing Enable High Magnitude Gene Induction upon Acute Activation of NK Cells

cell.com

During development, innate lymphocytes acquire defined sets of primed enhancers facilitating the rapid immune response. In this issue of Immunity, Sciumè et al. delineate the epigenetic changes...

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Enhancer/loops paper

@loops_enhancers

5 years

This account will be closed on tommorow. Please follow .@EnhancerLoop

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Enhancer/loops paper

@loops_enhancers

5 years

This account will be closed on Monday. Please follow .@EnhancerLoop

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Enhancer/loops paper

@loops_enhancers

5 years

This account will be closed on Monday. Please follow @EnhancerLoop

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Enhancer/loops paper

@loops_enhancers

5 years

Dear all on Monday this account will be closed. Please follow .@EnhancerLoop

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Enhancer/loops paper

@loops_enhancers

5 years

Dear all. Due to technical reasons, I'm going to close this account and start posting in new @EnhancerLoop. Please follow if you're still interested.

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Enhancer/loops paper

@loops_enhancers

5 years

academic.oup.com

Abstract. Here, Serrano-Saiz et al. describe the cis-regulatory logic of how neurotransmitter identity is imposed onto individual, distinct neuron types...

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Enhancer/loops paper

@loops_enhancers

5 years

Still surprised?. The 5' border of this sub-TAD is defined by a pair of CTCF sites. Surprisingly, we show that deletion of the CTCF binding sites within and downstream of the a-globin locus leaves the sub-TAD largely intact.

biorxiv.org

Mammalian genomes are subdivided into large (50-2000 kb) regions of chromatin referred to as Topologically Associating Domains (TADs or sub-TADs). Chromatin within an individual TAD contacts itself...

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Enhancer/loops paper

@loops_enhancers

5 years

epigeneticsandchromatin.biomedcentral.com

Background Chromatin physical interactions provide essential information for understanding the regulation of cis-elements like enhancers, promoters, and insulators in cell development and different...

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Enhancer/loops paper

@loops_enhancers

5 years

pnas.org

The regulatory specificity of a gene is determined by the structure of its enhancers, which contain multiple transcription factor binding sites. A ...

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Enhancer/loops paper

@loops_enhancers

5 years

Surprise, surprise. CTCF-dependent genome topology is not strictly required for a functional cell-fate conversion.

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@loops_enhancers

5 years

nature.com

Nature Communications - Obesity and type 2 diabetes (T2D) are metabolic disorders characterized by insulin resistance in skeletal muscle. Here, the authors map skeletal muscle enhancer elements...

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Enhancer/loops paper

@loops_enhancers

5 years

nature.com

Nature Communications - The relationship between regulatory elements, chromatin interactions and gene expression during development remains poorly understood. Here the authors present Tiled-C, a...

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Enhancer/loops paper

@loops_enhancers

5 years

nature.com

Nature Biotechnology - The location of genetic and epigenetic elements in mammalian nuclei is measured by gradual DNA fragmentation.

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Enhancer/loops paper

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biorxiv.org

Despite the well established role of nuclear organization in the regulation of gene expression, little is known about the reverse: how transcription shapes the spatial organization of the genome. In...

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Enhancer/loops paper

@loops_enhancers

5 years

biorxiv.org

Precise patterns of gene expression are driven by interactions between transcription factors, regulatory DNA sequence, and chromatin. How DNA mutations affecting any one of these regulatory ‘layers’...

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Enhancer/loops paper

@loops_enhancers

5 years

biorxiv.org

The probabilities that two loci in chromosomes that are separated by a certain genome length can be inferred using chromosome conformation capture method and related Hi-C experiments. How to go from...

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