Could EVs carry RNA therapies—safely & efficiently without viruses?. ✅ EVs deliver miRNA, mRNA, and CRISPR guides across the BBB & tumors with low immune risk. Read more about the review:

🚀 Nanobody + quantum microspheres detect aflatoxin B₁ at 0.03 ng/mL in just 8 min—10× more sensitive than gold strips! Precision food safety, no lab needed. 🔗

🧬Nanobody-based AuNP cluster LFIA rapidly detects survivin in urine—LOD just 3.90 ng/mL. Fast, stable & precise bladder cancer diagnosis in minutes, no labs needed!.🔗 #Nanobody #IVD #BladderCancer #Diagnostics #RapidTest

🔬 Nanobody rapid test detects NMP22 & survivin for bladder cancer:.•100% sensitivity, 90.9% specificity (dual marker strip).•Visual results in minutes.📖 Read:

🧬Modular EV targeting breakthrough: Fc‑EVs (antibody‑decorated) show 339 times cancer cell uptake & 180 times tumor accumulation, delivering doxorubicin effectively in mice. A new era for precision EV therapies. 🔗 #ExtracellularVesicles #CancerTherapy

✨ Nanobody Breakthrough in Zika Detection! 🦠. Nanobody test detects 1 ng/mL Zika NS1, results in 15 minutes ⏱️, no Dengue cross-reaction. Affordable, portable, and stable for 28 days 🌡️—ideal for self-testing. 🔗 #Nanobody #IVD #Diagnostics #Zika

🧬 Hybrid EVs hit ≈40% loading efficiency for siRNA/plasmids using a 30-min pH-triggered fusion with LCNPs—double the performance of passive methods. Surface proteins and function intact. 🔗 #EVResearch #GeneDelivery.

🎯 Nanobody raises extracellular pH by ~0.11 units.🚫 Blocks invasion (Ki ≈ 15.6 nM).🌬 Lung metastasis drops 50% → 13% in mice (~74% reduction).✅ No tumor shrinkage or toxicity.Oncotarget study 👇.

🚨Storing EVs in plain PBS? You might be losing 50–90% of your sample—even at –80 °C. 💡Add albumin + trehalose, and get 75–95% recovery—even after 26 weeks. Don’t let your buffer cost you results!.🔗

🧊Lyophilizing EVs without protection kills ~40% of vesicles and degrades miRNAs. 🧪 Adding trehalose or mannitolpreserves structure, cargo, and enzyme activity—even at room temp. 🔗Read the full study:

🔬How strong is your EV lysis buffer?.Mild buffer gently extracts surface markers like CD55/CD59. Moderate buffer boosts tetraspanins (CD9/CD81/CD63). Need deep cargo? Harsher lysis works—but requires cleanup. Which are you using? 🤔.

Nanobodies are revolutionizing cancer therapy by targeting the tumor microenvironment for precise drug delivery, including:.Glioblastoma Invasion Inhibition.Enhanced Imaging in Gastric Cancer.Targeted Photodynamic Therapy.Discover the latest research:

Storing EVs in PBS leads to ~40% loss over 10 weeks. PBS + 30% Glycerol: 22.7% reduction.PBS + 6% DMSO: 16.4% reduction.PBS + 25 mM Trehalose: Less than 10% reduction. Optimize your EV storage today! .

🐪Researchers have developed a synthetic humanised nanobody library combined with machine learning to identify potent neutralisers against SARS-CoV-2 variants. This approach reduced experimental screening by 78% for Omicron BA.5 and 90% for BA.1. 🔗

Milk-derived extracellular vesicles (mEVs) offer natural therapeutic benefits and can be engineered for targeted drug delivery, including oral administration. Learn more:

Bovine milk-derived EVs combat K. pneumoniae-induced oxidative stress & ferroptosis in bMECs, offering a natural mastitis remedy. Study:

Can humanized nanobodies match native performance?.Yes! A 2024 study shows CD19 CAR-Ts with humanized VHHs retained full cytotoxicity. 🔗

Plant nanoparticles from red cabbage cut gut inflammation by 50%! Engineered vesicles safely targeted and repaired colon damage orally. Future IBD treatment? 🌿.

Researchers engineered two nanobodies that bind to Ebola to neutralise viral particles in vitro. 🚀 The result:.•⁠ ⁠Animal Survival: 50% longer survival day. •⁠ ⁠Viral Load Reduction: Up to 1,000-fold decrease. Read more about the study:

🌳 Plant-derived extracellular vesicles (PDEVs) are emerging as sustainable, biocompatible nanocarriers for drug delivery. 📖 Dive into the latest research: