Journal of Leukocyte Biology
@jlb_journal
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Since 1964, JLB has published first-rate research on immunology-related topics, with emphasis on leukocyte physiology and behavior within the immune system.
United States
Joined January 2019
Mou's team shows how CCND2 mutation can serve as a second hit in acute myeloid leukemia with the AML1-ETO fusion gene, and inhibiting the mTOR pathway could be a therapeutic strategy for this subtype of leukemia in this article in the latest issue of #JLB.
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Febrile temperatures decrease the efferocytic capacity of proinflammatory macrophages. Learn more in this #JLB research article by Vetter and others .
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Fever with thrombocytopenia syndrome virus stimulates neutrophils to undergo NETosis, releasing neutrophil extracellular traps, whose DNA components downregulate IL-6, CCL3, and CCL4, resulting in liver and spleen damage. Read more by Ji et al #JLB.
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Check out this #JLB article by Glass et al to learn more about how macrophage polarization, inflammatory monocytes, and dysfunctional myeloid-derived suppressor cells contribute to the pathogenesis of immune aplastic anemia.
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Nervonic acid alleviates IMQ-triggered psoriasis in mice via inhibiting Th17/γδT17 infiltration and modulating the gut microbiota. Read all about it in this #JLB article by Yang and others
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Learn how acute alcohol intoxication triggers early inflammation and cell death, followed by immune suppression within 48 hours in healthy volunteers, in this research article by Sturm and others #JLB
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Check out this article by Kar Min Loh and others in the latest issue of #JLB to learn about the detrimental roles of innate immune cells in neuromyelitis optica spectrum disorder: Pathogenesis and therapeutic targeting
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From killers to hoplites. Learn how neutrophils contribute to skin barrier defense in this #JLB article by Lowery and others
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Read this #JLB News and Views article by Bruna Araujo David and Paul Kubes to learn about natural antibodies as frontline helpers in bacterial clearance .
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Expanding the role of the chemokine network—the multifaceted role of ACKR2. Read this editorial commentary by Bonecchi and Sozzani, and more in the latest issue of #JLB.
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Read about how hematopoietic stem and progenitor cells fine-tune the "sweet" of trained immunity in this #JLB review by Li and others .
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What's atypical about human B cells after allogeneic stem cell transplantation? Find out in this #JLB review by Bracken and others
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Check out this method by Elahi et al that uses pluripotent stem cells, with an expansion step to create high-yield conventional dendritic cells that respond to pathogenic ligands with a migratory phenotype, capable of stimulating T-cell proliferation #JLB
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Take a look at this #JLB article by Welhelm's team to learn how Afucosylated anti-HIV antibodies enhance antibody-dependent cellular cytotoxicity responses of natural killer cells against HIV-infected cells.
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Learn how PGE2 signaling via EP2 and EP4 steers pDCs toward a suppressive state and impacts the phenotype of tumor-exposed pDCs in this #JLB article by Cuenca-Escalona and others.
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UDP-glucose regulates dendritic cell mitochondrial respiration via a nitric oxide–dependent mechanism. Learn more in this #JLB research article by Vagher and others.
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Cavalcante-Silva and Koh show how depletion of natural killer cells enhances wound healing in diabetic mice in this research article in the latest issue of #JLB.
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In this #JLB article the Song team shows how mitochondria fusion reduces HIV infection via citrate.
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Take a look at the research of Mukherjee's team to learn how Neutrophil KLF2 regulates the developmental response to endotoxin in neonatal mice through the NLRP3 inflammasome signaling pathway. #JLB.
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