Congratulations to Dr. Heather Gibling (aka @hgibling) for an amazing PhD defence today! Thank you @ctitusbrown, @AMosesLab, @reimand and @PughLab for being on the examination committee. Great to work with you and @AwadallaLab on the most challenging parts of the genome

What is the largest publicly available haplotype reference panel? 1000 genomes? I'm looking for a pre-built pbwt index but don't want to go through dbGAP to get the HRC panel

The Donnelly Centre for Cellular and Biomolecular Research at the Univ of Toronto is inviting applications for three tenure track assistant professors. These are broad searches in the area of functional genomics (2x) and computational biology 1/2 https://t.co/E0qdWVYLwL

Super stoked to be joining MoGen @UofT as an Assistant Professor in Oct '22! I'm founding "The Laboratory for RNA-Based Lifeforms" to explore the diversity of Earth's RNA entities 🧬🔎🦠🌎! Looking to hire🥰! (Please RT) #RNA #genetics #virology #bioinformatics 1/3

Happy to share our latest work from @timp0 lab, modbamtools: Analysis of single-molecule epigenetic data for long-range profiling, heterogeneity, and clustering 👉manual and tutorial: https://t.co/5gZ7FuIFVX 👉preprint: https://t.co/4faXyC8FH2 some of the tools to highlight: 1/

Our next big thing! 🎉 "Verkko: telomere-to-telomere assembly of diploid chromosomes" from @MikkoRautiaine3 @sergeynurk @sergekoren generates beautiful graphs and automatically assembles 20/46 human chromosomes from HG002 #T2T without gaps https://t.co/6Jb0avtVmU

Interested in software development for biomedical and imaging data? With @hartjackson we're looking for a developer for an exciting academic/industry collaboration including some world-unique highly multiplexed imaging data Details ➡️ https://t.co/0bA5UbPWkg DMs open!

nanopolish v0.14.0 released, with support for modification bam files (thanks @BonfieldJames and @chrisnrg) and compiling on M1 macs

Today is the big day! The #T2T consortium is claiming victory and announcing that we have finally uncovered every last bit of the human genome! The papers are out today 🥳🧬 https://t.co/m8wgy09JBs

Join my team! Challenging but impactful projects, great colleagues, exciting science @OICR_news! https://t.co/cmeWTuONUz

Rust bioinformatics programmers: is there an idiomatic way of processing records of a bam file in parallel? Examples appreciated!

I've spent several years building software tools in genomics. While the work couldn't be more exciting, there are unique challenges and tensions in the world of scientific software. How does software in the life sciences actually work (and not work)? https://t.co/X4S6K8mFAw

Kar-Tong Tan found @nanopore basecallers often systematically call telomere repeats (TTAGGG)n into other repeats with similar signal profiles. He tuned the bonito basecaller and developed a pipeline to greatly reduce such errors. Read the thread and our preprint for details.

Thank you to my lab for the amazing nanopolish socks! I hope there's no bugs in this code, it would be very hard to fix now

Join us at @UofTCompSci! We are now hiring for tenure-stream faculty positions in multiple areas. We will start reviewing applications on December 6, and we will give full consideration to all applications submitted by January 10. Get the details: https://t.co/eCFRP7uzO7

Me and @YunWilliamYu's work on local k-mer selection techniques is now accepted to Bioinformatics! We investigate both practically and theoretically the properties of different local k-mer selection techniques, the most well-known being the minimizer.

Very excited to announce that we are recruiting a colleague for a full-time tenure stream position in the area of computational biology in the Donnelly Centre for Cellular and Biomolecular Research, in the Temerty Faculty of Medicine at the University of Toronto. 1/2

The CS department at Penn State is looking to fill several(!) faculty positions in bioinformatics. Initial deadline is Dec 1st, but we will consider all applications until the positions are filled. https://t.co/4O78YZECCy. Please RT if relevant to your followers. 1/3

Interested in a #postdoc position to develop new sequencing methods? Come work with us! Work includes but is not limited to epigenetics, RNA mods, and single-cell/spatial transcriptomics.

An ultra-long read update. Since @circulomics is "no longer available" for @nanopore people might be interested in these protocols from @longreadclub @NininUon and @DrT1973 - a toolkit of options here https://t.co/dNF7jjjcGi including monarch from @NEBiolabs - 🧵below with more.