Jan Kosinski
@jankosinski
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I solve molecular puzzles.
Hamburg, Germany
Joined June 2010
New method toward modeling cells and viruses! HMFF enables integrative membrane modeling and simulation guided by electron microscopy data. Created by Valentin Maurer and @MSiggel @EMBLHamburg @CssbHamburg, in collaboration with @WPezeshkian lab
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One month remaining to register for our conference!. Have a look at the outstanding speakers and programme, and use the link to join the 2nd edition of the Computational Structural Biology Conference in Heidelberg!.
Join us at #EMBOComp3D to explore cutting-edge breakthroughs in computational structural biology, AI, drug design, and innovative software! đź’». The programme offers a diverse range of sessions covering key topics, from molecular modelling to systems-level analyses and evolution,
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RT @EMBLEvents: Join us at #EMBOComp3D to explore cutting-edge breakthroughs in computational structural biology, AI, drug design, and inno….
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Check out HMFF and Mosaic on GitHub:.đź”—
github.com
Analyze and model biomembranes from 3D structural data. - KosinskiLab/mosaic
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For example, it allows building models like this filamentous influenza A virion ⬇️
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HMFF aids in on-membrane particle picking, supports multiscale modeling, and allows backmapping to atomic detail
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This enables physically realistic and complete membrane models of cells, organelles, and viruses, consistent with experimental data
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RT @EMBLHamburg: Congratulations, Thomas Schneider!. Thomas has been appointed permanent Head of EMBL Hamburg. We look forward to his conti….
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RT @JohnJumperSci: We are expanding our efforts in LLM-based scientific discovery and are hiring for several roles. Come join my team and w….
job-boards.greenhouse.io
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RT @WPezeshkian: New preprint: TS2CG v2, building and simulating membranes with any shape and lateral organisation. We got Martini Globe, M….
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Great work led by our PhD student Iuliia Kotova in collaboration with Fan Liu, @BorisBogdanow, Lars MĂĽhlberg, and Olivier Duss @OlivierDuss and Guelsah Gabriel labs. Structural analysis by our PhD student Konstantin Gilep.
biorxiv.org
Influenza A virus (IAV) exploits the host cellular machinery to facilitate its replication, yet many host-IAV interactions remain unexplored in the cellular context. Detailed information about...
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We captured a snapshot of in-cell protein contact sites during influenza A virus infection. In-cell crosslinking, AlphaFold modeling, and functional follow-ups revealed new host factors and mechanisms. A step toward modeling the infected cell.
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RT @CssbHamburg: Check out this video summary of the first day of our upcoming symposium "Mechanisms of Infection - from structure to trans….
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RT @EMBLEvents: Join us in Heidelberg for the second edition of the EMBO Workshop 'Computational structural biology'! 🧬. Explore cutting-ed….
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RT @EMBLEvents: ⏰ You have until 3 March to submit your abstract and be part of the EMBO | EMBL Symposium "Infection: pathogens, hosts, and….
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RT @CssbHamburg: The fourth and final speaker in the Parasites session of our symposium is Ron Dzikowski from The Hebrew University of Jeru….
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RT @amjjbonvin: I have two open postdoctoral researcher positions in my group. Looking for applicants with interest and expertise in comput….
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RT @kagglingdieter: 2) continue here but use my reach, to at least have a positive impact on a platform that becomes more and more filled w….
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RT @kagglingdieter: Excited to share that Eugene Khvedchenia and I secured 🏆 1st place out of 950 teams in the CryoET Object Identification….
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RT @biorxiv_bioinfo: gapTrick - Structural characterisation of protein-protein interactions using AlphaFold with multimeric templates https….
biorxiv.org
Motivation The structural characterisation of protein-protein interactions is a key step in understanding the functions of living cells. Models of protein complexes provide important insights into...
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RT @OVKovalevskiy: #AlphaFold v3.0.1 is out! Contains various efficiency and usability improvements alongside a collection of minor bug fix….
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