Put this on your RADARS: our latest work on Reprogrammable ADAR Sensors for cell type targeting A team effort by Chen lab members Jeremy Koob, @dawnchenx, & Yifan Zhang in collaboration with @idmjky, @RohanKrajeski, @jgooten, @omarabudayyeh, & AbuGoot lab Tweet added by Fei Chen Lab @insitubiology

Fei Chen Lab

2 years

Put this on your RADARS: our latest work on Reprogrammable ADAR Sensors for cell type targeting A team effort by Chen lab members Jeremy Koob, @dawnchenx , & Yifan Zhang in collaboration with @idmjky , @RohanKrajeski , @jgooten , @omarabudayyeh , & AbuGoot lab

Programmable eukaryotic protein expression with RNA sensors

The diversity of cell types and states can be scalably measured and defined by expressed RNA transcripts. However, approaches to programmably sense and respond to the presence of specific RNAs within...

www.biorxiv.org

1

28

146

Fei Chen Lab

@insitubiology

2 years

Check out @jgooten 's tweetorial for more details:

Jonathan Gootenberg

@jgooten

2 years

Genome editing owes a huge debt to genome sequencing With efforts like @humancellatlas , we’re sequencing cells like mad. What is the "Cas9" of single cell? With @omarabudayyeh @insitubiology : RADARS, for programmable cell-specific sensing/expression 🧵👇

8

100

494

1

0

1

Fei Chen Lab

@insitubiology

2 years

Or if you prefer, @omarabudayyeh 's:

Omar Abudayyeh

@omarabudayyeh

2 years

Today we report in @biorxiv programmable RNA sensors that express any protein gated on specific RNAs in a cell. Much like gene sequencing necessitated gene editing tools, we answer “What is the Cas9 of single cells?” 🧵👇🏼w @jgooten & @insitubiology 1/17

9

162

647

0

3

Replies