
Imogen Ramsden
@imogen_ramsden
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BBSRC LIDo PhD Student | Cell Signalling, Molecular Biology, Biochemistry 🔬🧬 | @LIDo_DTP @UCL @uclbiosciences | Music enthusiast 🎶 | Forever curious 🔍
London
Joined August 2024
Back to back conferences - having wrapped up the Small G proteins meeting, landed in Istanbul heading to the 24th FEBS Young Scientists’ Forum ( #YSF2025 ) held in the stunning region of Sapança!.Thanks FEBS for awarding me a YSF travel grant!. @FEBSnews.#FEBS2025 #BiochemEvent.
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💬 Loved asking questions, learning from so many great discussions and connecting with scientists across different backgrounds. Thanks to @BiochemSoc for organising such a brilliant #BiochemEvent!.
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Final Session 6 SGP2025:.🎯 Biomechanical signatures & potential targets in cancer.🧬 Rho and Cdc42 regulation via PTMs, localisation & degradation in cancer and immunodeficiencies.⚙️ Nuclear force feedback loops via Rnd3 modulate actomyosin tension. @BiochemSoc #BiochemEvent.
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Last day of the #SmallGproteins meeting, great evening last night meeting researchers in the field hearing about people’s journeys, and gave advice on expressing a phosphorylated GTPase. Looking forward to Session 6 kicked off by @VickySanzMoreno!. @BiochemSoc #BiochemEvent.
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SGP25 Sessions 4 & 5:.🧬 Lipid sensing, β-catenin, and phosphorylation reshape GTPase signalling.⚙️ Mechanical forces & trafficking: nuclear F-actin, actin-Rab27a, plexins, & COL1.⚡️Cancer cell adaptation through RhoA, Rac1 SUMOylation, and KRAS rewiring.@BiochemSoc #BiochemEvent.
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SGP25 Session 3:.Theme of molecular glues….⛓️ Tri-complex inhibitor as molecular glue for oncogenic RAS.💊 Combining inhibitors to combat KRAS-driven cancer.🎯 p120RasGAP molecular glue targeting RAS.🔢 Mathematical modelling to study RAS activity.@BiochemSoc #BiochemEvent.
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SGP25 Session 2 (Part 2):.🧬 RAP1GDS1 isoform regulates KRAS signalling & lysosomal function in lung adenocarcinoma.❓Oncogenic KRAS may not alter Akt/ERK pathways.☠️ p190RhoGAP paralogs show synthetic lethality in endometrial cancer. @BiochemSoc #BiochemEvent.
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SGP25 Session 1 (Part 2):.🧫 Overcoming RAS resistance: biobanks & precision medicine.💊 Adaptive immunity enhances KRAS inhibitor activity.🔬 Organoids reveal allele-specific tumour growth.💥 Plus ARL15, RhoGDI1, RalGEF, SOS1/2 & proteomics pipelines.@BiochemSoc #BiochemEvent.
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SGP25 Session 1 (Part 1):.⛓️ Mapping KRAS interactomes in organoid models.🧬 Isoform-specific KRAS: one mutation, big difference.🔬 Novel tool tracks Ras mutation dynamics in vivo.✨ And a reminder that clear science communication empowers patients!.@BiochemSoc #BiochemEvent.
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Just kicking off at the Small G Proteins Meeting 2025 after lunch meeting scientists from all over the world - Barcelona, Connecticut, New York - and it’s encouraging to see a programme with both early career researchers and group leaders presenting!.@BiochemSoc.#BiochemEvent.
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Excited to be selected as one of the Social Media Contributors at the #BiochemEvent Small G Proteins Meeting next week, thanks to @BiochemSoc. I look forward to hearing about and discussing the latest research in the area as well as presenting my own PhD work about Arf proteins!
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🚨 Excited to share my first preprint! 🚨. I developed a bioinformatics pipeline to identify novel drug targets in multidrug-resistant bacteria as part of my Master’s research. Check it out here:
biorxiv.org
Antibiotic resistance poses a global health crisis. In order to develop new antibiotic agents, it is crucial to identify drug targets in multidrug-resistant bacteria. Criteria for such a target are...
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A fortnight ago I had the chance to present my PhD research at #Biologists100 — gave a flash talk, presented my poster, and had great chats at the brilliant ECR careers session. Big thanks to @Co_Biologists & @Official_BSCB for the opportunity!.📸 Full post + photos on LinkedIn
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