MRI is noninferior to biopsy in eosinophilic fasciitis - Dr K Shaw #CCRE25

“Nothing about lupus is easy.” - Dr Petri #CCRE25

Eosinophilic fasciitis (Shulman disease) needs IV pulse steroids. Poor prognosis relates to delayed diagnosis and lack of high dose steroids (as opposed to SSc where you want to avoid high dose steroids) #CCRE25 Dr K Shaw

For every 1 mg increase in prednisone, risk of organ damage in the future goes up by 3% including osteonecrosis - Dr Petri #CCRE25. You can’t even get away with 1 month of high dose steroids!

Lupus panniculitis can mimic breast CA - Dr K Shaw #CCRE25

EULAR2023 #SLE guidelines say keep pred < = 5 mg/d.- Dr Petri #CCRE25

With CAPS (catastrophic APS)- Rx with complement inhibitors (reduces mortality) -Dr Petri #CCRE25

Pearl: SPTCL can mimic lupus panniculitis - Dr K Shaw #CCRE25

Add other DMARD/biologics to HCQ if #SLE is active (not just increase steroids) - #CCRE25 -Dr Petri

Top causes of death in #SLE.1. SLE.2. CV disease .3. cancer.4. Infection.Socioeconomic and educational and racial disparities contribute to mortality #CCRE25 Dr Petri

How to taper glucocorticoids: don’t let others sabotage your plan (eg ER visits for type II symptoms, patients self dosing) - get patients on board - Dr Petri #CCRE25

Model to predict thrombosis in #SLE .Low C3+LAC + activated platelets (PC4d)>20 net Mean Fluorescence Intensity (MFI) predicts thrombosis/ history of thrombosis Dr Petri.#CCRE25

Seeing a patient with seronegative RA is an opportunity to consider another diagnosis at every visit. - Dr Cush @RheumNow #CCRE25

CV risk is assc with disease activity, prednisone, LAC and low mean C3 - Dr Petri #CCRE25

Hickam’s dictum is the opposite of Occam’s razor. The dictum states a patient’s symptoms can be due to multiple diagnoses - Dr K Shaw #CCRE25

Pearl: false positive syphilis tests with Antiphospholipid is low titer. When you see high titers despite neg confirmatory test. Image is of secondary syphilis before and after penicillin - Dr K Shaw #CCRE25

Grateful for the opportunity to present at #NYRIF and #CCRE25 in Destin, FL!.Thankful for the insightful feedback from Dr. John Cush @RheumNow and all the NYRIF team. A special thanks to my mentors for their continued support. Truly a valuable and unforgettable experience!

Different labs can vary in results of Antiphospholipid Ab - be careful. Dr Petri shared results of JHU lab discrepancy compared to QUEST labs in this pt with APS who typically is positive #CCRE25.

Thank you Dr. @Kahlenberglab for sharing such valuable insights into the emerging therapeutic avenues for Lupus! Your detailed explanation of the postulated etiopathogenesis of lupus was truly enlightening as well 🔆. #CCREast #CCRE25 #rheumatology

Thank you for sharing these valuable insights from #CCRE25! The recommendation for a 4:1 mix for LAC testing is crucial, especially considering the prevalence of false positives in 1:1 mixes. This adjustment can significantly enhance our diagnostic accuracy in SLE patients.