Oxygenated Implant Sustains Insulin Cells in Rats, No Immunosuppression. An oxygen-generating implant keeps high-density insulin-producing cells alive in diabetic rats for months without immune suppression.@Cornell.#celltherapy #diabetes #insulin.

Bayer, Kumquat Target KRAS Variant in Up-to-$1.3B+ Cancer Collaboration. @Bayer will partner with Kumquat Biosciences to develop Kumquat’s KRAS G12D inhibitor, which could generate $1.3 billion-plus for the San Diego biotech. #KumquatBiosciences #cancers.

Potential Triple Negative Breast Cancer Target in EPIC Long Noncoding RNA. Knocking down EPIC1 sensitized triple negative breast tumor-bearing mice to immunotherapy with the PD-1 inhibitor pembrolizumab.@PittTweet.#breastcancer #immunotherapy #noncodingRNA.

AI-Designed DNA Repair Templates Improve Gene Editing Precision. The #AI tool, named “Pythia,” predicts how cells repair their DNA after #CRISPR editing and opens the door to next-generation gene therapies.@SLienkamp @XenoThomasnaert @UZH_en .#DNArepair.

Therapeutic Candidates for Difficult Targets Emerge. Recent developments in protein-protein interactions (PPI) give hope for patients with advanced or untreatable diseases.#RevolutionMedicines #enzymes #genes #proteins.

Rat Brain Reveals Code for Learned Skills, Clues into Human Movement Disorders. The #basalganglia in rats uses separate codes for learned movements and “natural” behaviors, offering insights into human #movementdisorders.@kiahhardcastle @Harvard.#brain.

Sartorius Stedim Biotech and Nanotein Technologies Partner to Boost Cell Therapy Manufacturing. Sartorius Stedim Biotech and @nanotein plan to develop additional products for the expanding cell and #genetherapy markets.@SartoriusGlobal.#biomanufacturing.

Mitochondria-Targeted Receptor Counters Neurodegeneration in Mice. A tool, called mitoDREADD-Gs, improves memory in Alzheimer's and #dementia mouse models by boosting mitochondrial activity.@Inserm @univbordeaux @umoncton.#Alzheimersdisease #mitochondria.

Don't miss out! In this eBook, we dig into the crux of DNBSEQ’s technological advance while highlighting the global impact of the technology as illustrated by over 10,000 research papers spanning more than 5,000 species. DOWNLOAD: @MGI_Technology

Alzheimer’s and Parkinson’s Research Advanced with Low-Cost "Ring-Inserts". The "ring-inserts" can be combined with drug testing, genetic engineering, viral delivery, or high-resolution imaging techniques.#MedicalUniversityofInnsbruck #Alzheimers.

T7-ORACLE Foretells Functional Proteins by Accelerating Evolution. The #syntheticbiology platform accelerates protein evolution thousands of times faster than nature for broad therapy applications.@scrippsresearch.#proteins #antibodies #enzymes.

Conserved T-Cell Targets May Boost Universal Coronavirus Vaccine Development. A new #vaccine design pipeline could protect against emerging SARS-CoV-2 variants and pinpoint conserved T-cell epitopes across #respiratory viruses.@ljiresearch.#Tcells #COVID19.

CRISPR Screen Uncovers How Macrophages Respond to Pathogens. Researchers developed a method to dissect immune-regulatory programs via integrative time-series analysis and high-content CRISPR screening.@MedUni_Wien.#AI #CRISPR #macrophages.

Self-Assembling Nanoparticles at Room Temp Could Transform Drug Delivery. Researchers plan to collaborate on preclinical trials to apply polymersomes to real-world vaccine or drug delivery challenges.@UChicagoPME.#drugdelivery #nanoparticles #vaccines.

StockWatch: Sarepta Says Deaths of Two Elevidys Patients Posted on FDA Database Unrelated to Treatment. @Sarepta said Friday that the deaths of two patients taking Elevidys® were unrelated to their use of the #DMD treatment. #genetherapy #drugdevelopment.

🧬 Get ahead of biotech’s next big breakthroughs at #StateOfBiotech 2025 — streaming live Sept 24. Join leading scientists, executives & innovators as they discuss AI, CRISPR, emerging therapeutics, & trends shaping biotech’s future. Free to attend → 🔗

Novel CHO-K1-Based Transient System Mirrors Stable Cell-Line Quality. As drug developers face mounting pressure to accelerate discovery timelines without sacrificing quality, QLNS-CHO offers a compelling solution. #antibodies #CHO #drugdevelopment.

Lactose-Eating Yeast Boosts Yields and Cuts Costs for Cell-Free Protein Synthesis. This generally-regarded-as-safe #yeast can be a cost-effective production vehicle for #enzymes and #antibodies, as well as heterologous #proteins.@imperialcollege.

Biomanufacturing Industry Leaders to Discuss Latest Geopolitical Dynamics. The speakers hope to stimulate conversation about how regions can remain competitive while becoming interdependent.@landmarkbio.#biomanufacturing #AI.

Sanofi All In on Digital Drugmaking. Digitization has allowed Sanofi to optimize manufacturing and automate document preparation.@sanofi.#AI #automation #biomanufacturing.