A.n.n.
@fireflyann
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volunteer #CRCSM librarian #BRAF & #NRAS FB grps Stage 4 CRC Support & Colon Cancer Stars trials Stage 2/3 pts https://t.co/48vU5493pH
Bay Area, California
Joined June 2009
Started a BRAF Colorectal Cancer Public Library group on Facebook. So many significant trials, research findings, changes to NCCN guidelines, etc. in the last 2 years. Gathering high level research/interviews into 1 place seems wise and useful. #BRAFCRC
https://t.co/1FjFjY9AOU
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Congratulations to Dr. Scott Kopetz! @RueschCenter chose well for the 2025 Luminary Award! Really easy to say a lot of great things about Dr. @skopetz ... but, really -- it's all so true and his career has been so impactful for BRAF colorectal cancer patients around the world.
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Now is your last chance to register for the Pittsburgh Third Annual GI Cancer Summit! We will soon be gathering to discuss the latest research and insights. If you are thinking of making last-minute plans, be sure to register via the link below.
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Dr. @smitha42 @FightCRC Research #ASCO25 updates discussed DSP107, a first-in-class bi-specific 4-1BB T-cell engager, w/ & w/o atezolizumab in MSS mCRC pts NOW: Phase 2b trial to open 10 US/Australian sites NCT07235293 PI: @AnwaarSaeed3 at 35 minutes https://t.co/Q918WPoMuT
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new title for the trial at @MSKCC_OncoNotes A Study of Botensilimab and Balstilimab for Colorectal Cancer With ctDNA+ After Surgery and Chemotherapy NCT07227636
Delighted to see this! MINIMAL RESIDUAL DISEASE TRIAL Phase II Study of Adjuvant Botensilimab in Comb W/ Balstilimab in Pts W/ Colorectal Cancer & Persistent Circulating Tumor DNA Following Surgery & Chemotherapy 284 pts Kudos to @MSKCancerCenter @segaln @ldiaz1971
#MRD
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$SMMT Summit Therapeutics Announces Expansion of Ivonescimab Global Phase III Development Program with HARMONi-GI3 Study in 1L Colorectal Cancer https://t.co/NAlWagqOnU
stocktitan.net
Summit launches global Phase III HARMONiโGI3 to compare ivonescimab+chemo vs bevacizumab+chemo in ~600 1L metastatic MSS CRC patients; PFS primary endpoint; US sites to activate this quarter; prior...
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๐๐ถ๐ป๐ฑ๐ถ๐ป๐ด ๐๐ต๐ฒ ๐๐ฒ๐๐ ๐๐ฟ๐๐ด ๐ณ๐ผ๐ฟ ๐ฎ ๐ฆ๐ฝ๐ฒ๐ฐ๐ถ๐ณ๐ถ๐ฐ ๐๐ฎ๐ป๐ฐ๐ฒ๐ฟ: ๐ฎ๐ป ๐จ๐ฝ๐ฑ๐ฎ๐๐ฒ ๐ผ๐ป ๐ง๐ฟ๐ฎ๐๐ฒ๐ฟ๐ฎ | #CuriousDrGeorge & Dennis Watson, VP Business Development of Travera: https://t.co/HRo0ANarXS
#CancerGuidance #CancerTreatment #PrecisionOncology #TraveraRTG
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more countries! be the first or second profile from yours! Note: future development so patients can search by multiple countries Hoping of use for oncologists in the community with heart - but little time for research.
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Apropos of 1st #ESMOAI25 A Canadian Stage IV colorectal cancer patient developed a FREE trial matching website - w/ AI matching & explanations. Initially just for Canada, https://t.co/2HWZGN9ydY, now global. Launched 11/1/25 Matches in minutes @myESMO
https://t.co/oQaIBD9ahG
Sometimes a great notion... Early Onset Stage IV crc patient Dillan Eisenhaur has created FREE trial matching service that ALSO adds in an AI capability. He saw GAPS in trial services & created a website to help ALL patients. https://t.co/u8hiTSD56q My comments 1/X
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๐ฏ โFrom variant to value.โ @loic_verlingue shares how multimodal AI assistants are transforming the Molecular Tumor Board โ integrating genomics, imaging & clinical data into one intelligent layer to guide truly precision oncology decisions. #ESMOAI25
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Delighted to see this! MINIMAL RESIDUAL DISEASE TRIAL Phase II Study of Adjuvant Botensilimab in Comb W/ Balstilimab in Pts W/ Colorectal Cancer & Persistent Circulating Tumor DNA Following Surgery & Chemotherapy 284 pts Kudos to @MSKCancerCenter @segaln @ldiaz1971
#MRD
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A phase 1 study of E7386, a CREB-binding protein (CBP)/ฮฒ-catenin interaction inhibitor, in patients (pts) with advanced solid tumors including colorectal cancer: Updated dose-escalation part NCT03833700. #GI23 #CRCSM
https://t.co/PkQ7QqXiSW
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Enrollment is now open for our randomized dose optimization study of E7386 in combination with other anticancer drug(s) in patients with endometrial carcinoma.
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Sutro Biopharma to Highlight its Next-Generation Exatecan and Dual-Payload ADC Programs in Presentations at AACR 2025 $STRO
lifesciencereport.com
SOUTH SAN FRANCISCO, Calif., April 28, 2025 (GLOBE NEWSWIRE) -- Sutro Biopharma, Inc. (Sutro or the Company) (NASDAQ: STRO), an oncology company pi...
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๐จ #ESMO25 #mCRC โ Phase II OPTIPRIME (FFCD 1605) explored a stop-and-go FOLFOX + panitumumab strategy in RAS/BRAF WT mCRC (n=115) ๐ฏ Median duration of disease control = 24.9 mo (90% CI 19.3โ28.3) ๐ฅORR 74.8% at induction โ 45% 1st reintro โ 25% later reintros โช๏ธOS 36.1 mo
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727MO: OPTIPRIME study, FOLFOX + Pani "stop-and-go" strategy โ
Duration of disease control 24.9 mo โ
1st re-introduction ORR: 45.0% โ
OS 36.1 mo ๐Want to know toxicity profiles including neuropathy with oxaliplatin re-introduction #ESMO25 @myESMO @OncoAlert
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A Prospective Feasibility Study Using ctDNA to Tailor Neoadjuvant Chemotherapy for Patients With Colorectal or Appendiceal Adenocarcinoma At @MDAndersonNews PI: Michael White, MD Opened December 2024 ctDNA testing before CRS or HIPEC NCT05947838 https://t.co/5R3VtMAphF
#CRCSM
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