Sami El-Boustani
@elboustanilab
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Neuroscientist at University of Geneva, Associate professor studying the neurobiology of cognition.
Geneva, Switzerland
Joined December 2018
The El-Boustani lab at @UNIGE_en is recruiting! We are looking for PhD students and Postdocs to study synaptic plasticity underlying sensorimotor learning in mice using brain-wide mapping, dendritic imaging and more. More details at https://t.co/90DirIgSMO. Please RT
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(7/7) A huge thank you to our wonderful collaborators at the @GjorJulijana lab (TUM) and to @unige_en, @snsf_ch, and @FensKavliNet for supporting this work! Read the full paper in @NatureComms: https://t.co/CvmDQqokiF
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(6/7) We uncovered a wide network of cortical areas for visuo-tactile processing and pinpointed a single one of them that holds an abstract representation of peri-personal space used to generalize learned behaviors.
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(5/7) By substituting real stimuli with targeted optogenetic activation of RL sub-domains, we showed that this area alone can elicit generalization behavior.
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(4/7) By selectively silencing synaptic transmission in various cortical areas, we discovered only area RL in the dorsal stream is necessary for generalizing across modalities, revealing a critical hub for bridging vision and touch.
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(3/7) Using wide-field and two-photon calcium imaging, we uncovered overlapping visuo-tactile spatial maps within the dorsal cortex. Many neurons responded to both whisker and visual inputs with same spatial preferences, revealing a shared, modality-independent representation.
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(2/7) We trained mice on a spatial discrimination task, first using touch in the dark, then vision in the light. Remarkably, they could instantly apply the same learned rule after switching modalities!
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If you can see it, you can feel it! Thrilled to share our new @NatureComms paper on how mice generalize spatial rules between vision & touch, led by brilliant co-first authors @giulio_matt & @GtnMaelle. More details in this thread 🧵 (1/7) https://t.co/CvmDQqokiF
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Mice observe action-outcomes from other conspecifics to update their own understanding of the environment during foraging behavior. Curious about these results? Check out poster PS06-28PM-093 by Anas Masood on Friday afternoon. #FENS2024
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Social cues influence decision-making under uncertainty. Learn how mice adapt their decisions to different conspecifics and which brain circuits might be involved at posters PS06-28PM-094 and -095 by Dimokratis Karamanlis and Andrea Valderrama on Friday afternoon. #FENS2024
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How fast do real and simulated mice learn sensorimotor associations, and how are these learning trajectories impacted by motivational states? @giulio_matt addresses these questions at poster PS03-27AM-208 on Thursday morning (Decision-making). #FENS2024
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Curious about how the brain uses abstract representations of peri-personal space to generalize goal-directed behavior across sensory conditions? Check out poster PS03-27AM-114 by @GtnMaelle and Charlie Foucher on Thursday morning (Cortical Sensorimotor Integration). #FENS2024
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How does the visual cortex build flexible and efficient sensory representations? Is unsupervised learning the solution? Dive into the learning algorithms behind visual system’s adaptation to its input statistics in our review with Eugenio Piasini & @davide_zoccolan!
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Nominate your Mentor or an outstanding PhD Thesis for the #FKNE #Mentoring and #PhDPrizes! Both prizes will be awarded at #FENS2024. https://t.co/ZSPj5TNlQy Deadline: 15 Feb. 2024 #neuroscience #mentorship
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How mice can transfer spatial knowledge from vision to touch and vice versa? Come check out Maëlle Guyoton (@GtnMaelle) and Giulio Matteucci’s (@giulio_matt) poster AA25 at #SfN2023 Saturday (11/11) PM in the session (PSTR030.04). #visuotactile #decisionmaking #generalization
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Young PI in Neuroscience? This FKNE workshop is for you! We will help you define what it means to be a great mentor and leader and provide practical tools to achieve this. For more details and registration
The #FKNE Leadership and Soft Skills Online #Training Course for the Starting PI is open! Don't miss the opportunity to enhance your abilities and learn to tackle challenging moments as an early group leader! Application deadline: 15 Nov. 2023 👉 https://t.co/8nz2vwJ4l7
@FENSorg
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For junior or mid-career stage neuroscientists with an independent position in Europe, excellence in track record & committed to contribute to improve Neuroscience in Europe: Submit your application to join the FENS-Kavli Scholars! Deadline: 10 April 2023 https://t.co/IOQEWUlXLO
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Are you a junior or mid-career stage neuroscientist with an independent position in Europe, excellence in track record and also determined to contribute to improve Neuroscience in Europe and beyond?Then join us!The FENS-Kavli Scholars call is now open! https://t.co/W5S4LnonMz
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Excited to share our new manuscript on a novel #neuropeptide family that regulates #feeding across #evolution. Kudos to @Pat_TFrancisco for tackling this challenging project and coming up with the name @marmite . #homeostasis
https://t.co/I5yvTNjFNj 1/22
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The University of Geneva is seeking a faculty member at the Assistant Professor level who is pioneering independent research programs using innovative approaches in psychiatry neuroscience. Please do not hesitate to contact me if you have questions #neur… https://t.co/1sC7Styl36
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