Brian D. Dynlacht Lab
@dynlacht
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A transcription lab gone rogue because we also study the primary cilium........
Manhattan, NY
Joined November 2018
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@AngryBlackLady
Irma Sánchez replies : The common theme is AMERICAN. Queen Elizabeth's II uncle resigned as king because he married an American divorcee. Not acceptable. Meghan fell into that category too.
English divorcees, however , are suitable spouses & consort to the King of England.
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We are doing some really exciting science in the lab.
We may not be HHMI , we still make our own buffers and everyone has their own lab job including me and Irma- but I can guarantee that you will learn a lot and have fun doing it. Join us!
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When I first started grad school, I thought I wanted to work on cancer. But then I realized that there was a lot of basic biology out there that needed to be understood before tackling aberrant biology. How do you fix a broken machine if you don't understand how it works ?
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Imagine being a faculty member and hearing a representative of the administration say publicly in front of students that only 2 other scientists at your institution have done at least as much scientifically as a person currently under consideration for the faculty ?
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@leelab_nyu
@jallepap
My wife, Irma Sánchez raises an important point.
College professors are never certified as teachers.
A PhD does not a teacher make. The state of New York requires CERTIFICATION to teach the 1st grade for eg.
As educators, we should get this training too.
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@KellieMeyerNews
@ossoff
@WSAV
@WJBF
@wrblnews3
Bravo Senator Ossoff. Now THAT is responsible public service.
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@jaketapper
Jake, stop spreading this stuff. The truth is probably somewhere in the middle. Cuomo did a better than average job of protecting our state from dangerous federal leadership. Judge not, lest ye be judged.
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We have an amazing faculty past and present.
Our students should know that mountains of CNS papers, HHMI funding , and lots of NIH grants etc do not always identify what is AMAZING science.
I encourage our students to read the papers of faculty and judge for themselves.
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@HenMazzig
Nasreen Youssef and Eyad Yousef are heroes and saints. They risked their lives to save their neighbors. We hope the state of Israel formally thanks them for this tremendous act of courage.
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@FrankieDHeyward
Agree, but I think if the government subsidize daycare for newborns, they should do it for all Americans, not just scientists. American taxpayer money pays for our education, and subsidizes to a large extent, our professional life. Daycare help should be for everybody.
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Check out this article: Irma Sanchez PhD comments : Does this mean King Charles reserves the right to rescind all gifts that his mother
gave to other family members ? Not a good way to
start his term......
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@ElenaEcon
@rdhernand
My wife who is POC and is also scientist, advises you to complain about this reviewer. That reviewer is penalizing you for doing well.
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@XavierBecerra
@HHSGov
Thanks, and my Mexican American wife who is a scientist, is thrilled about your appointment. She is confident that you will will bring the issue of diversification of the scientific workforce in the USA to the POTUS. The NIH needs to invest in a diverse scientific work force.
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Years ago, Joe Heitman sent Irma this, he was applying for a job at NYU and didnt get it. This is the lab notebook page when he found and named TOR. He has never gotten the credit for it, that he deserved.
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@YoniMichanie
Jews ALL of us will never forget October 7th, 2023.
It affected ALL of us i;n the Diaspora.
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@BiologyCarly
Sorry, but Grace Gill PhD a former colleague has had manicured polished nails for as long I have know her (decades). She had her own lab at HMS and then
Tufts. The HMS and Tufts search committee didn't care about the red nail polish.
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@HarmitMalik
@FritzLaylin
@gbaucom
@NatureComms
My wife says that many women often mentor
unofficially. She credits a member of her thesis committee, a woman as her true mentor.
My wife, is nontenure track, so she cannot have her own students, and yet has mentored students for over a decade, unofficially.
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@bariweiss
Who told you that this is true ? I would say that every single scientist in this country is important. Scientifically he has made important contributions, but so have many, many other people. To suggest otherwise, is simply
not accurate.
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@DrAnneCarpenter
@chrstn_e
Indeed, I am leaning toward a system like what the physics community does - dump it all online and then people can evaluate it for themselves including tenure committees. That would level the playing field.
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So,my better half Irma Sánchez PhD got promoted has been a long wait for her, but she has earned it and now she has it. She sends her thanks to all her supporters.
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@solome_haile
Congrats. and If it is your first choice, accept it and then consider withdrawing all your other applications. That will give someone else
a chance to get their first choice.
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2 postdoctoral positions open in my lab , see Nature Careers ad. Check us out !
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@davidvanvalen
@lpachter
Indeed, a classmate of ours who is Mexican American, once said "why aren't we allowed to be average ?, They are ."
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@ycinnewyork
@LiuNewYork
Irma Sanchez PhD replies : Shame on you.
Affirmative action protected you and gave you opportunities you would not have had. Dont delude yourself about that . AA also provided protection for Native Americans. But, it is obvious , you dont care about that at all.
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Irma and I are pleased to report that NIGMS has approved a supplemental grant to our cilia R01 to sponsor a post bacc opportunity to a Hispanic student.
biochemistry and cell biology. Looking forward to helping them become the scientist they want to be.
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@FlyBehaviour
@HarmitMalik
Please do not villainize Boomers. I don't know any Boomers who "took the benefit and then removed it for those that came afterwards." State colleges in Texas BTW are good deal even for out of staters.
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@HenryYin19
@HarmitMalik
You should also point out also the difference in the SOURCE of the salary for tenure track profs. At a university (not medical school), the SCHOOL pays 75% of salary and benefits (9 months). At a med school, the PROF pays 50-80 % of salary/benefits from grants.
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@thiagoarzua
If your boss puts you on the exact same project
as someone else - bail. My wife bailed her 1st postdoc, 3 other postdocs in the lab had the same project! 12 months later in another lab, she had a 1st author Nature paper. Don't be afraid to do what is best for you.
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@LabeledLines
Institutions these days in the USA are not hiring, and when they do they are not looking so much at the science but rather the potential to bring in grants which brings in overhead money for the institution. Basic science grants don't bring in much money. Good luck.
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@lpachter
@DrAnneCarpenter
@nprscience
Irma Sánchez PhD replies: Scientists unfortunately marginalize each other's work all time by not citing their work appropriately or minimizing their scientific contributions. We don't expect to ever get a Nobel,
but have had our science minimized - it hurts and is wrong.
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@DrAnneCarpenter
@CarolynBertozzi
My wife, Irma Sánchez PhD Cal class of '92 says ! of her science heroes was Marie Curie. She learned about her from a book at the age of 12,and noticed 2 things 1. Marie was a woman and 2.Maria was married. So she thought, it is possible to have love and job too.
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@jbendery
@Sifill_LDF
Not surprising at all to us and my wife and I agree
with the president of the National Congress of American Indians.
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@JeffreyRMillman
😀 You are doing a good job outside of science.
Compassion and generosity from 5 year old is terrific.
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@fleshball
In my lab, if you contribute data to a figure in the paper you are on the paper. it is not about what people want, it is what is fair.
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@AuschwitzMuseum
@deniswirtz
The day before the Warsaw ghetto was closed , my grandfather Joseph paid someone to smuggle his young son, my father out of the Warsaw ghetto. He never saw his parents again. They probably were sent to Treblinka.
May the memory of Huguette be a blessing.
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@jaketapper
Maybe Ivanka's rabbi can give him a Sabbath "waiver",
like she and Kushner got for the Presidential Inaugural balls.
And yes, I am being sarcastic.
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@IzackTenorio
My wife, Irma Sánchez PhD also Mexican ( UC Berkeley Class of 1992) sends you "muchas felicidades". Here she is at age three. My best wishes as well.
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@deniswirtz
@MDAndersonNews
@letswinpc
@CancerCenterIL
@sloan_kettering
@PennCancer
@BrownUCancer
@NCI_CSSI
@NCIPhySci
@theNCI
Indeed, and the NCI has failed to understand that
they should invest more in the basic science of NORMAL biology. If we really understood how normal biology actually works, then I think we could really make some real advances in cancer.
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@dna_heligrace
Read a paper, if you like the science and want to do more in that lab. Send an email to the PI of that lab- ask them if they have a spot open and give them a start date. That is how I did it and actually that is the best way to do it.
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@AshaniTW
Yes, and the same would be true for review of
NIH grant applications. Our trainees are the ones principally generating the data for the lab publications.
Are NIH reviewers unaware of the difficulties labs trainees and their PIs have faced in the last 2 years?
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@takaki_komiyama
@CytoLabKoc
This is unacceptable. Scientists should let the community know which journals subject authors to this kind of unprofessional review of manuscripts. That way we will know when to boycott that journal and send our manuscripts elsewhere.
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Today is our anniversary, which for us is the day I invited her out for coffee (Berkeley date), 34 years ago. Where did all that time go ? My best friend and she can cook too.
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@YSPTSPS
@OdedRechavi
I think that it is essential grad students should consider the teaching environment in the lab, from the advisor to the postdocs and senior grad students.
If people in the lab are totally out for themselves, don't go there. I was lucky, I had many teachers in the Tjian lab.
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@VdangioE3lab
@schierlab
@NatureComms
I agree that particular paper has problems, but a lot of good work has been published at NatureComms.
I think it wrong to delegitimize their work by implication.
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@HenMazzig
AD 409 – After throwing off their allegiance to Constantine III in 408, the local British populace expel the final remnants of Roman authority in 409.
This is what Britain WAS. Why is the British parliament enabling a threat to democracy in the UK now ?
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@NHGRI_Director
Irma Sánchez PhD replies : unfortunately, this day should remind us of how the contributions of women scientists have been marginalized for decades. Dr Franklin's data was viewed and used without her permission. They got a Nobel Prize in 1962, she died of cancer in 1958
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@SharpeFiona
@britishmuseum
Irma Sanchez PhD replies : Protests on the grounds and entrance/exits of museums, schools, universities, and hospitals should classified as punishable crimes
by the government. Protests bloc king businesses as well.
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@ColinZamecnik
You have addressed an important issue. Even senior people
are leaving the academia for industry/pharma. Ray Deshaies, Aviv Regev come to mind. He made the "jump" as he put to Irma. Go where you think you can make an impact.
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@HarmitMalik
Bullying in our profession is, unfortunately, not an isolated event. It happens to all of us, but more so to junior people
and especially to women and people of color. Securing $$$ seems to be now equivalent to scientific excellence which of course is not true at all.
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@Amelia_Lindsey
Irma's favorite is Jennifer Lippincott Schwartz. Her papers have such clarity, she says that high school student would actually understand the gist of what was being discussed. Beautiful, clear, unpretentious writing.
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@UiisesPerez
@STEMhasSoul
Irma Sánchez PhD replies : Ulises, I got a similar kind of review for a NSF fellowship many years ago. I wonder why the NSF continues to support these kinds of reviews ? Believe in yourself !
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@leslievosshall
@theNASciences
Understandable, but know that many people of color like my wife who is Mexican American, are very uncomfortable when gender is used as evidence of diversity. White women have the principal beneficiaries of affirmative action in the sciences according the NSF.
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@DrAnneCarpenter
@chrstn_e
This would reduce the politics, pettiness, incompetence and unfairness in the review process. It would also save a lot of money ( no need for journals) and could be used for other purposes ( like more conferences) so we can DISCUSS the science- face to face.
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@Sifill_LDF
Indeed, I would add that some child survivors of the Holocaust also do not know their birth date, including a member of my family. Thanks for this insight about Frederick Douglas. He is a hero of mine.
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@RepJerryNadler
@nytimes
Thank you Mr. Nadler for pointing out that it is possible to get an excellent secular education in yeshivas.
What is needed now is educational reform in the NYC yeshivas . Maimonides was a physician, spoke several
languages and studied Talmud as well.
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@AdrianoAguzzi
@CytoLabKoc
Yes, I am convinced that scientific reviews are highly suspect these days. A reviewer should be able to summarize in 3 or 4 sentences the principal merits or weaknesses of the paper. Otherwise, I suspect that reviewer cannot be objective about the manuscript under evaluation.
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@HarmitMalik
@politico
No, it is not good- if it is true. But, as we all know this kind of behavior is not uncommon. We all have witnessed this kind of behavior directed toward students, women, postdocs even tenured faculty.
We must all have the courage to make it stop.
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This just came out ... not sure what to think .....
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@superrsema
Sounds familiar, when Irma and I were grad students, the landlord tried several times to raise our rent 10% or more. He was not successful and complained that
Irma "arm wrestled" him about it, and so he had to submit to her argument.
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@JessicaCalarco
@DrAnneCarpenter
Irma Sanchez PhD replies : The idea that admitting the most academically successful students inherently would cultivate a diverse student body is wrong. I would think this would cultivate homogeneity.
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@KSchaferPhD
Irma Sánchez PhD replies : Indeed, and the other way around applies too. Trainees should be aware that
most advisors work really hard to keep the lab going (grant applications, adminstrative headaches etc)
It really helps when someone in the lab says thank you.
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It was fun hosting Fatima in our lab this summer. We are hopeful that she returns to us after graduating next spring to do postbacc research in the Dynlacht lab.
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@Nancy_Kanwisher
It is a call for the elimination the state of Israel : From the Jordan River to the Mediterranean Sea.
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@jaketapper
The young people in the USA, who are the future of the USA- need to speak up by voting in 2022 OUT those members of Congress who supported these measures.
And the media, like CNN need to do more than just tweet about this.
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@stephenfloor
@rdhernand
Try not compare, because at the higher levels it is not about what you achieve, half of it or more is politics.
You have no control over that. Focus on the science - they can't take that from you.
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Day 1 in the lab at last. Always looking for postdocs,
anybody interested ? Transcription, genomics and/or centrosomes/cilia - take your pick.
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@ProfDAHammer
I gave up on them long ago. NSF thinks my work is too
"medical" , but being at a medical school my work is not
viewed as "basic." Go figure.......
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@StuPolitics
My dog Happy, a mutt died years ago when I was a student at Yale. Best friend I ever had.
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@pmddomingos
No, affirmative action is the practice or policy of favoring individuals belonging to groups known to have been discriminated against previously. Indeed, my wife, Dr. Sánchez just pointed out that you may have been a beneficiary of this policy.
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@KYT_ThatsME
Senior PIs should get mandatory training too.
Some junior PIs have left science because their senior
advisors provided no mentoring or support at all.
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@millerlab
Indeed, I am not above cleaning out freezers, making LB, and even helping do experiments to finish a paper. This PI is a jack of all trades, tech, bench scientist, prof and sometimes handyman as needed. Oh yes, and I am legally responsible for everything.
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@jodikantor
@jaketapper
I wonder why it is that it took so long so deport him.
My paternal grandparents did not survive WWII because of people like him. They were in their 30s when they died leaving their only son, my father - an orphan.
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@lauradelongwood
Grant reviewers are only supposed to evaluate the science nothing else. Talk to the SRO.
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@HenMazzig
Irma Sánchez PhD replies : This Rice alum and a Jew by choice supports you. Excluding Jewish students is simply racism.
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Everyone, I , Irma Sanchez am tweeting this.
I would say to everyone out there that unless it has personally happened to you, you have no idea how women feel when it happens to them.
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@DrNancyPadilla
The GRE is a few hours, a Bachelor's degree is about 4 years. Data wise, it makes no sense at all to make a decision based on one data point.....
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@kenHkolb
@HarmitMalik
Yes,and how about just promoting the one (probably) faculty of color that you may have ?
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@blekhman
You forgot to point out that the direct costs on that
R01 were about $300 k. That just leaves $210 left to
spend on other salaries, fringe and supplies. Most
PIs have no more than 2 R01s. And we have to pay at least half of our salaries and fringe......
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Postdocs/students must be educated about costs to run a lab. Eg. Med school profs must pay 60% of salary + benefits (~32% of salary) fr grants. Students/Postdocs cost the prof 100% stipend + ~32% more for health insurance - fr grants. What is left for supplies ? Do the math.
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@BeAScientist
I suggest that you take it up with the head of HHMI, who is BTW - a woman. I trained in the same lab as Erin, I can assure you that she is committed to increasing diversity in science and promoting women. Fellows are chosen based on the strength applicant/mentor TEAM.
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@ItaiYanai
Indeed, that would be most people I know.
My PhD advisor has been there for me , since I joined his lab in 1988. He even wrote a letter that helped me get my coop apt 10 years ago. My trainees know that all they have to do is ask, and I will do what I can.
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@franklinleonard
@jallepap
Please, legacy admits flood the medical school/ MD PhD/ law school classes at a much higher rate than valedictorians of color.
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@EylonALevy
@jallepap
@AP
Ah yes, we can have complete confidence that the media housed in that location is going to tell the truth and then feel safe moving forward.
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@NYC_DOT
@NYCMayorsOffice
How about protecting PEDESTRIANS from e-bikes,
and bikes. Every day people get hurt because BIKERS
don't think traffic rules apply to them and won't stay off the sidewalks.
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Why is it always about money ? When did it all become about scientists bringing in money for their host institutions and NOT about institutions supporting the efforts of their scientists ?
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@rburdine1
Irma Sánchez PhD replies : Institutions place little value on what we do. They ask us to pay 50% or more of our salary, and in addition impose grant expectations of multiple R01s which then they can use the indirect costs to pay the other 50% .
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@eric_lander
@JoeBiden
This is great, how about having grants automatically get a proportional increase each time the NIH increases postdoc salaries? Right now, the response of investigators is to eliminate a position, because their grants were not funded
to meet future pay raises.
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