defeatHIV
@defeatHIV
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defeatHIV investigates #genetherapy approaches to an #hivcure or the control of HIV without daily therapy.
Based @FredHutch Seattle
Joined January 2012
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The first clinical trial participant has been treated with an experimental CAR-T cell therapy, a “living drug” that could lead to an
#hivcure
, or long-term HIV remission without antiretroviral drugs, according to an announcement from
@caring_cross
.
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92
344
Using an animal model, researchers have identified a window of opportunity for introducing a treatment that promotes remission of HIV infection.
#hivcure
0
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134
Research into
#hivcure
is ever-changing as new discoveries are made and scientists report additional rare — but informative — cases of individuals likely cured of
#HIV
.
@TAGHIVscience
offers an overview of the current state of the science.
0
56
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A potential one-dose treatment to 'functionally cure'
#HIV
will be tested in human trials
#hivcure
#genetherapy
4
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122
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43
111
Unlocking HIV cure: Study highlights allogeneic immunity as key mechanism in eradicating latent virus reservoirs
#hivcure
0
36
103
“I’m going to keep fighting until I just can not fight anymore,"
@TimothyRayBrown
says about the return of his leukemia.
#hivcure
2
25
93
Adam Castillejo
@londonpatient
today has celebrated his 5th anniversary of the transplant that cured him of cancer and
#HIV
!!
We congratulate him on this milestone, wish him years more, into a future with many more brothers & sisters to join his
#hivcure
family!
💋💋💋🎉🍾💋💋💋
3
17
94
It always seems like an
#hivcure
remains 10 years away.
But some people are optimistic and feel like those 10 years are closer than they've ever been.
3
13
85
University of Pittsburgh School of Medicine scientists have identified drug candidates that show promise to reverse the ability of HIV to escape detection by the immune system.
#hivcure
2
27
91
A new pre-clinical study in nonhuman primates will evaluate an experimental drug’s potential use as a
#genetherapy
that could prevent people who have
#HIV
from having to take daily antiviral drugs for the rest of their lives.
#hivcure
1
22
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The abilities to reactivate latent
#HIV
reservoirs, inhibit HIV infection, and induce latent cells to die off make
#obatoclax
worth investigating for development as an ideal LRA for use in the “shock and kill” approach.
#hivcure
2
29
73
For every person that we get onto ART, there are two people who have newly acquired the virus.
We'll never treat our way out of the epidemic.
All the money we put towards ending
#HIV
will have been for naught.
In this way, we all need an
#hivcure
.
#getinvolved
#getinformed
3
24
73
I Am Now Officially Participating in HIV Cure Research—And You Can Too!
#hivcure
#clinicaltrials
6
12
69
CAR/CXCR5-T cell treatment is safe and holds promise as a future treatment for the durable remission of
#HIV
.
#immunotherapy
#genetherapy
1
25
64
Functional cure and after advanced HIV disease following 7-years of antiretroviral treatment interruption
Poster from AIDS 2014 is about the same woman in the case report we tweet 2 days ago:
#hivcure
1
31
66
Scientists have cured a handful of people of
#HIV
by piggybacking on treatments they received for blood cancer.
But does that bring a widespread cure any closer?
3
14
61
Paul Edmonds, 67, a man dubbed as California’s ‘City of Hope’ patient, has become the fifth person in the world to be cured of HIV.
#hivcure
1
17
62
A hypothetical
#hivcure
in a model lowered HIV prevalence and prevented future acquisitions over time, which increased life-years, reduced the number of individuals on ART, reduced AIDS-related deaths, and more.
In Kenya, it needs to cost less than $5400.
0
15
59
Thirty years ago yesterday, April 21, 1990, ACT UP held a massive demonstration at the
@NIH
, when more than 1,000 demonstrators marched through the sprawling grounds of the campus.
1
17
61
What progress has been made toward an
#hivcure
?
The short answer is, “It’s complicated.” But there is hope.
1
21
57
So, why do we think an
#hivcure
might be possible?
Below you will find 7 good reasons, including our dearly departed
@TimothyRayBrown
.
This chart is from "Prevention, treatment and cure of HIV infection"
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The RIO clinical trial will test whether a new type of therapy can keep HIV under control without daily antiretroviral treatment (ART) tablets.
#hivcure
0
23
51
This
#genetherapy
study marks the first instance of combining a dual gene-editing approach with antiretroviral medications to successfully cure animals of
#HIV
.
#hivcure
1
21
49
A virtual memorial service for Timothy Ray Brown, the first person to be cured of HIV, will be held Tues Feb 16, 2021 at 9am Pacific / 12pm Eastern
Register here:
Please share this with anyone who is interested in joining!
#hivcure
2
29
52
The US FDA has approved a first-of-its-kind CRISPR-based gene therapy trial, with the ultimate aim of achieving an
#hivcure
0
16
50
The protocol for clinical-scale manufacturing of HIV-specific and HIV-resistant CD4 T cells is an important step toward effective
#immunotherapy
for
#HIV
disease.
#hivcure
#genetherapy
2
17
46
Could an HIV Cure Be Based on the Same Breakthrough as the New Treatment for Sickle Cell?
#hivcure
#CRISPR
@BodyPROHIV
0
14
50
Two patients have received infusions of an investigational chimeric antigen receptor (CAR) T cell that targets the
#HIV
envelope glycoprotein gp120.
#hivcure
#genetherapy
0
25
48
Recent advances have led to developments in immunotherapeutic approaches towards
#HIV
remission or cure.
#hivcure
#genetherapy
#immunotherapy
0
15
47
WANNA GET INVOLVED WITH THE WORK TOWARDS AN
#HIVCURE
?
Come learn about opportunities for communities to collaborate around the progress the field has achieved thus far.
30 July 13:15-14:15
Global Village Channel/Room 1
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Scientists are getting a better sense of the risks and benefits of treatment interruptions in
#hivcure
-related research.
0
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One of the most common and persistent questions we hear in the world of HIV is: Is HIV potentially curable?
The short answer is, “it’s complicated,” but there is hope.
And it depends on what is meant by the word “cure.”
#hivcure
0
12
45
A very small phase I clinical trial has tested an anti-HIV strategy involving an adeno-associated viral vector-based gene delivery system that instructs cells to pump out antibodies that block
#HIV
.
#genetherapy
#hivcure
2
13
38
Here is a recorded webinar series to discuss with community the complex science behind
#genetherapy
strategies to curing or controlling
#HIV
without using antiretroviral therapy.
(Everything you'll want to know but didn't know to ask!)
#hivcure
0
16
45
Yesterday we spoke to Drs. Kamel Khalili and Trish Burdo about their work using
#CRISPR
to cut
#HIV
out of our DNA. They've cured mice & nonhuman primates so far. Next is a phase 1
#hivcure
#clinicaltrial
in people with HIV being conducted by
@ExcisionBio
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The 22nd International
@AIDS_conference
#AIDS2018
took place in
#Amsterdam
from July 23–27, 2018. Here,
@PosAware
summarizes key highlights on
#HIV
cure-related research from the conference
#hivcure
2
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"I didn't want to be the only person cured," Timothy said.
"I wanted to do what I could to make a cure possible. My first step was releasing my name and image to the public."
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