David Daines
@daviddorg
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One of a kind N=1s | Investing in human flourishing | Bitcoin
SF
Joined February 2018
In 2026, I’m going to do something many will see as crazy… I’m going from 12h+ of screen time per day down to 0. For an entire year. And? I’ll be sharing periodic neuroimaging, 100+ monthly blood markers (@superpower), continuous sleep data, video updates, and more. All
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30 observations from spending 3 months in my small off grid cabin: 1. I always wake up right before the sun peeks over the mountain. And once I'm awake, there's never a desire to nap. 2. I’ve always been prone to migraines—probably from working 12 hours a day on a screen—but if I
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The Microplastics N=1 visual explorer is now live. → Interactive time-series charts → % change by particle size range → Protocol, stats, costs, limitations → Raw lab PDFs + supporting files for transparency High-dose phospholipids seem useful, but more research is needed
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10/ In Closing: → Plastic is omnipresent in our environment and our bodies (yes, it's everywhere—including up to 0.5% of mass in autopsied brain samples) → Many risks are known, but the magnitude of effect in any given person is highly uncertain. → High-dose BodyBio PC is
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9/ In any case, here's what I do if I re-ran the experiment and went for max reduction in blood microplastics instead of just isolating the phospholipid complex. Quite simply, I'd hit all three pieces of the equation. 1. Minimize Inflow → Water filtration (reverse osmosis
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8/ Why did things turn around so drastically? Let's start with a simple model that explains how plastic particles move through the body. They come in through ingestion, inhalation, IV/cuts, and potentially direct skin contact. They move through the body, sometimes traveling
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7/ Over the duration of the experiment, I consumed ~180 fl. oz. of the phospholipid complex, adding up to ~11 16 fl. oz. bottles. (Yes, fairly expensive, which is why I gladly accepted BodyBio's offer to supply me for this N=1) To recap a bit: after a ~67% decrease in a mere 4
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6/ Ok, onto the next potential mechanism: augmenting bile flow and/or altering bile composition. One of the functions of bile is to carry out lipophilic (fat loving) waste, which could include smaller plastic particles (and certainly other far smaller plastic associated
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5/ Important sidebar: AFAIK, the Blueprint test does not quantify any nanoplastics, which are likely much more abundant in our bodies. The smallest bucket reported on the test is simply "<10μm." Based on a third-party attestation I obtained, the test is accurate at least from
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4/ It started with a marketing graphic I was extremely skeptical of. This graphic represents a case study performed by BodyBio with the same protocol I followed, demonstrating a dramatic reduction in a wide variety of both water and fat soluble contaminants. Again, I doubted
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3/ It's very simple. For six months, I consumed 1 fl. oz. of this phospholipid complex every day (a very high dose), split into two doses (with breakfast & dinner): (No financial relationship, though BodyBio did supply me for this N=1) I also did my best to control anything else
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2/ If we look at particle size ranges (test range is approx. 1μm-70μm), we see a notable pattern. There were 1) more smaller particles, and 2) the smaller the particles were, the less they decreased. The same general pattern is present even when we include month 6. We'll discuss
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1/ First things first. Here is what months 0-4 looked like on my protocol: a 67% reduction across all particle sizes. So you can imagine my surprise when the trajectory changed so much in months 4-6. But what was my protocol and why did this happen? I'll get there very soon.
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I reduced the microplastic particle count in my blood by 67% in 4 months with a new method. Feb 2025: 42 particles (2.1 million/5L of blood) Apr 2025: 23 particles (~1.2 million/5L of blood) Jun 2025: 14 particles (700 thousand/5L of blood) Then my levels rebounded... Aug
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