Mauro D’Amato
@damato_mauro
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for those interested, here are our original studies on the genetics of sucrase-isomaltase deficiency in IBS, including lookup in #lowFODMAP treated patients.
gut.bmj.com
Recently in Gut and elsewhere,1–3 rare and common hypomorphic sucrase-isomaltase ( SI ) gene variants have been linked to an increased risk of IBS. Similar to congenital SI deficiency (a form of...
@DoctorTennyson @umfoodoc @BMoshiree @NYSGE Congenital Sucrase-Isomaltase #CSID was one of the most important things that I learned at #DDW19 from @umfoodoc
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for example, latest evidence.Functional Variation in Human CAZyme Genes in Relation to the Efficacy of a Carbohydrate-Restricted Diet in IBS Patients - Clinical Gastroenterology and Hepatology
cghjournal.org
Limiting the dietary intake of certain carbohydrates has therapeutic effects in some but not all irritable bowel syndrome (IBS) patients. We investigated genetic variation in human Carbohydrate-Act...
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our latest work on sucrase isomaltase gene variants in #IBS is out in @AGA_Gastro. is sucrose the culprit for postprandial symptoms in some IBS patients because of carbohydrate maldigestion?.
gastrojournal.org
Sucrase isomaltase (SI) is an intestinal brush border disaccharidase key to the digestion of dietary carbohydrates via its enzymatic breakdown of sucrose and starch.1 Hypomorphic (defective) SI...
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RT @AGA_CGH: Genetic variation in human CAZymes, the enzymes responsible for carbohydrate digestion, may affect the efficacy of carbohydrta….
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RT @BenchSideStory: LARGE SCALE GENETIC STUDY FINDS NEW LINK BETWEEN IRRITABLE BOWEL SYNDROME & CARDIOVASCULAR SYSTEM. With.Dr. Leticia Cam….
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here the press release associated with the publication📢. Genetic study links defects in sugar digestion to irritable bowel syndrome, via @EurekAlert!
eurekalert.org
A new study has uncovered a key genetic mechanism that increases the risk of irritable bowel syndrome (IBS) and worsens bowel symptoms in individuals who carry defective copies of the sucrase-isoma...
our latest work shows sucrase (and not isomaltase) drives genetic risk of #carbohydrate maldigestion. is sugar a culprit causing bowel symptoms?. potential to design personalised carb-focused diets for #IBS prevention and treatment.
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our latest work shows sucrase (and not isomaltase) drives genetic risk of #carbohydrate maldigestion. is sugar a culprit causing bowel symptoms?. potential to design personalised carb-focused diets for #IBS prevention and treatment.
gastrojournal.org
Sucrase isomaltase (SI) is an intestinal brush border disaccharidase key to the digestion of dietary carbohydrates via its enzymatic breakdown of sucrose and starch.1 Hypomorphic (defective) SI...
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thanks @BenchSideStory for interviewing me, was fun working with you guys!.
CAUSAL GENES AND PATHOGENIC MECHANISMS UNDERLYING GASTROINTESTINAL DISEASES. Professor Mauro D’Amato @damato_mauro.Professor of Medical Genetics, Department of Medicine and Surgery,.LUM University @universitalum in Casamassima, Italy &.Ikerbasque Research Professor and Head of
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🔥3yr #postdoc position available in my lab for a computational biologist to lead research in #genetics, #genomics and #metagenomics of gastrointestinal diseases🔥. want to know more?.
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RT @fake_journals: Finland Publication Forum will downgrade hundreds of Frontiers and MDPI journals | @RetractionWatch | .
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so glad to see this confirmed with adequate numbers after our initial observation almost 20 years ago. !.
pubmed.ncbi.nlm.nih.gov
DeltaF508 heterozygosity might exert a protective effect in CD.
Analysis of sequencing data of 320k individuals (75k cases and 245k controls) shows heterozygous carriers of cystic fibrosis mutations are protected from inflammatory bowel disease. The protection mechanism could be due to an altered gut mucosal barrier that resists penetration
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nice piece about work in @elcorreo_com . gracias por destacar nuestra investigación!. El deseo irrefrenable por lo dulce también es innato y se hereda.
elcorreo.com
Un grupo internacional con participación vasca demuestra la existencia de una anomalía genética que nos hace propensos a la comida con azúcar, lo que abre las puertas a f
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predicting #Crohns disease up to 16 years before diagnosis using protein biomarkers. amazing work led by Olle Granno and @jonashalfvarson - thanks for having me onboard.
gastrojournal.org
This study shows that a combination of proteins measured in blood can be used to predict a future diagnosis of Crohn’s disease.
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RT @CICbioGUNE: #bioGUNE_Research | 🍫 Could genetics help curb our cravings for sugary snacks?. 🔬 Researchers from @damato_mauro #CICbioGUN….
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RT @Peter_Aldiss: Absolutely delighted to have my latest paper out in @AGA_Gastro with @MetteK_And and @damato_mauro . .
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RT @UoNPressOffice: A study published @AGA_GAstro led by @Peter_aldiss @UoN_BDI @MedicineUoN has found that a genetic flaw might be key to….
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@Peter_Aldiss @AGA_Gastro @CICbioGUNE @Ikerbasque @universitalum and here the press release, which is getting some traction in the media.
eurekalert.org
New research has found that people with a genetic defect in their ability to digest sucrose eat less cake, sweets and chocolate, which could hold the key to helping the wider population to eat less...
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collaborative work with @Peter_Aldiss Mette K Andersen and many others, published in @AGA_Gastro .@CICbioGUNE.@Ikerbasque .@universitalum.
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our latest work is out, with a twist: .sucrase-isomaltase gene not only relevant to #IBS risk but also to dietary intake and preference of sucrose-rich foods. potential for personalising prevention and treatment of metabolic and digestive diseases.
gastrojournal.org
Excess intake of dietary sugar is established to be a contributor to obesity and type 2 diabetes, and a subset of carbohydrates poorly absorbed in the small intestine are recognized triggers of—and...
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thans @JohannahRuddy for highlighting our work.based on this and previous work, CAZyme genotype might turn out to be useful info both for the diagnosis and treatment of a subset of #IBS patients experiencing symptoms because of carbs maldigestion.
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