Charles Gauthier
@charlogauthier
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Professor of chemistry @inrsciences. City councillor of Péribonka. Husband and Father. Chess and piano player. Runner. Gardener. *Views expressed are my own.*
Laval & Chicoutimi (Québec)
Joined June 2009
Exciting breakthrough from our lab! We've synthesized potent Lewis-X-containing triterpenoid saponins that block HIV-1 attachment to immune cells via DC-SIGN & L-SIGN, showing promise as antiretroviral agents. @inrsciences @SFU @FRQ_NT
chemistry-europe.onlinelibrary.wiley.com
The convergent synthesis of Lewis-X-containing betulinic acid and echinocystic acid saponins (1 and 2) is presented. The synthetic saponins were shown to inhibit, at the low micromolar range, the...
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My PhD student, Oscar Gamboa, successfully defended his doctoral thesis last week at the Centre Armand-Frappier in Laval. Congratulations, Oscar, on your outstanding efforts within my research team. Wishing you all the best in the next steps of your journey! @inrsciences
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Journals can’t find peer reviewers. Preprints aren’t taken seriously. Garbage papers slip through peer review. Meantime, AI is slowly taking over. Nature describes the current situation. I highly recommend reading the article. 📍 The summary (+ my comments): 1. We are facing a
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This is still the picture Harry Potter uses for his lab website
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We sincerely thank Prof. Charles Gauthier for invited contribution on 'Synthesis and pharmacological evaluation of nature-inspired phenacyl glycosides' for VSI-Richard Schmidt issue of Carbohydrate Research. https://t.co/10DRZCfwRx
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L’UQAC et l’INRS contribuent à des avancées majeures contre le VIH "via @LeQuotidien_Cyb"
lequotidien.com
Une équipe de chercheurs de l’Institut national de la recherche scientifique (INRS) a réalisé une avancée majeure dans la lutte contre le VIH grâce à une molécule présente dans l’écorce de bouleau.
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Du Fjord au Lac, en passant par les monts Valin jusqu'aux rives de la rivière Péribonka… C’est la fabuleuse histoire d’un royaume que nous célébrons aujourd’hui. Bonne Fête du Saguenay–Lac-Saint-Jean! 💙⚜️
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My NIH R01 sub-award for HIV research is being discontinued due to US administration policies, effective Aug 1st, 2025. Multiple funding cuts like these can have serious consequences for public health. @inrsciences #HIVresearch
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In our latest collection of #free #education #resources, we explore #carbohydrate #chemistry with Professor @charlogauthier and his PhD student Oscar Gamboa from the @inrsciences in Canada. How can we create synthetic carbohydrates and investigate their biomedical applications?
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We are delighted to share that BHU under the Auspices of ACCTI is hosting ‘CARBO-XXXIX: International Conference on Emerging Trends in Glycoscience and Glycotechnology” from 21-23/11, 2025. Looking forward for your active participation. https://t.co/8r50rD1jCu
etgg-bhu-2025.in
Join us at Banaras Hindu University for Carbo-XXXIX, an international conference on emerging trends in glycoscience and glycotechnology from November 21-23, 2025. Engage with experts and explore...
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Bravo !
Motion unanime de l’@AssnatQc demandant la fin de la monarchie au Québec. « Que l’Assemblée nationale affirme sans équivoque qu’elle est seule dépositaire de l’expression démocratique du peuple québécois; Qu’elle souligne qu’une très forte majorité de Québécois et Québécoises
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#EurJOC Synthesis of Rhamnose-Modified Lewis-X-Containing Saponins (Charles Gauthier and co-workers) @charlogauthier •
chemistry-europe.onlinelibrary.wiley.com
The synthesis of triterpenoid saponins bearing a Lewis-X trisaccharide analogue, in which the fucose residue is replaced by a rhamnose, is presented. These saponins, designed as negative controls in...
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Lewis-X-Containing Triterpenoid Saponins Inhibit DC-SIGN- and L-SIGN-Mediated Transfer of HIV-1 Infection (Charles Gauthier @charlogauthier and co-workers) #openaccess 🔓
chemistry-europe.onlinelibrary.wiley.com
The convergent synthesis of Lewis-X-containing betulinic acid and echinocystic acid saponins (1 and 2) is presented. The synthetic saponins were shown to inhibit, at the low micromolar range, the...
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Le @RQRMedicaments lance son concours de bourses pour stagiaires d’été en chimie thérapeutique. Deux bourses de 5 000$ sont disponibles pour des projets de recherche en chimie thérapeutique. Date limite : 16 mai 2025. Info :
rqrm.ca
L’axe Découverte de composés et chimie thérapeutique lance son concours Bourses pour stagiaires d’été en chimie thérapeutique 2025. Cette année, 2 bourses d’une valeur de 5 000$ chacune destinées à...
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Just published in Eur. J. Org. Chem.! We pepared triterpenoid saponins featuring a Lewis-X analogue with L-rhamnose replacing L-fucose. These compounds were used as controls for antiviral and immunological studies targeting DC-SIGN. https://t.co/pFSoUWrz3J
@inrsciences
chemistry-europe.onlinelibrary.wiley.com
The synthesis of triterpenoid saponins bearing a Lewis-X trisaccharide analogue, in which the fucose residue is replaced by a rhamnose, is presented. These saponins, designed as negative controls in...
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Immunological and Toxicological Assessment of Triterpenoid Saponins Bearing Lewis-X- and QS-21-Based Trisaccharides (Alain Lamarre, Charles Gauthier @charlogauthier and co-workers) #openaccess 🔓
chemistry-europe.onlinelibrary.wiley.com
The synthesis of betulinic acid and echinocystic acid saponins featuring QS-21 minimal immunogenic motif is reported. These chimeric saponins, together with previously synthesized Lewis-X-containing...
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Republicans are now defending the use of foreign concentration camps. We are inching dangerously close to repeating the darkest chapters of history. If Trump can deport people—without due process—to El Salvador’s prisons simply by claiming they’re here illegally, what’s to stop
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Donald Trump has already lost control of the tariff narrative completely. As long as he remains in office, this is a crisis with no resolution. He has proven himself to be an erratic and untrustworthy trade partner, an abuser of the global economic system. He offers no stability
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Exploring new vaccine adjuvants: We synthesized QS-21 analogues with betulinic acid & evaluated their immunological & toxicological profiles. Great collaborative work with Prs Alain Lamarre and André Pichette! #QS21 #adjuvants @inrsciences @UQAC
https://t.co/re5A2jtcgg
chemistry-europe.onlinelibrary.wiley.com
The synthesis of betulinic acid and echinocystic acid saponins featuring QS-21 minimal immunogenic motif is reported. These chimeric saponins, together with previously synthesized Lewis-X-containing...
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