Cystic Fibrosis papers
@cf_papers
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Tweeting latest #cysticfibrosis papers from Pubmed | Created by / report issues to @williammflowers cystic fibrosis 🫁 #RespEd
Joined June 2023
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Introducing my sister account @cf_papers! Auto-tweeting the latest PubMed #cysticfibrosis papers and bioRxiv preprints. Follow to stay up to date!.
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Investigation of Zur-regulated metal transport systems reveals an unexpected role of pyochelin in zinc homeostasis
pubmed.ncbi.nlm.nih.gov
The mechanisms underlying the remarkable ability of Pseudomonas aeruginosa to resist the zinc sequestration mechanisms implemented by the vertebrate innate immune system to control bacterial infect...
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Malonate is relevant to the lung environment and induces genome-wide stress responses in Pseudomonas aeruginosa
pubmed.ncbi.nlm.nih.gov
Versatility in carbon source utilization is a major contributor to niche adaptation in Pseudomonas aeruginosa. Malonate is among the abundant carbon sources in the lung airways, yet it is understud...
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Universal azole prophylaxis for prevention of coccidioidomycosis among lung transplant recipients transferring care to a center within a highly endemic region
pubmed.ncbi.nlm.nih.gov
Azole antifungal prophylaxis was associated with a low rate of coccidioidomycosis among lung transplant recipients relocating to the highly endemic region.
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Protein expression changes in Tibetan middle-to-long distance runners after the transition from high altitude to low altitude: Implications for enhancing endurance training
pubmed.ncbi.nlm.nih.gov
The study aims to investigate the differences in protein expressions in Xizang's (Tibetan) middle-to-long distance runners after the transition from high altitude to low altitude and reveal the...
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Disparities in outcomes by race and ethnicity in the Canadian cystic fibrosis population
pubmed.ncbi.nlm.nih.gov
There is an urgent need understand why outcomes for Canadians with CF differ between white and non-white individuals, including the role of socioeconomic circumstances.
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Disparities in outcomes by race and ethnicity in the Canadian cystic fibrosis population
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Social support for the chronically ill during lockdown. Qualitative research in the COVID-19 pandemic
pubmed.ncbi.nlm.nih.gov
Chronic illness requires a web of actors, both professional and familiar, who constitute the support network of the chronically ill. This article aims to analyse how the COVID-19 pandemic has...
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An automated pipeline for computation and analysis of functional ventilation and perfusion lung MRI with matrix pencil decomposition: TrueLung
pubmed.ncbi.nlm.nih.gov
TrueLung quickly delivers functional maps and quantitative outcomes in an objective and standardized way, suitable for radiological and pneumological assessment with minimal manual input. TrueLung...
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The lysogenic filamentous Pseudomonas bacteriophage phage Pf slows mucociliary transport
pubmed.ncbi.nlm.nih.gov
Pseudomonas aeruginosa is a major pulmonary pathogen causing chronic pulmonary infections in people with cystic fibrosis (CF). The P. aeruginosa filamentous and lysogenic bacteriophage, Pf phage, is...
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Regulatory adverse drug reaction analyses support a temporal increase in psychiatric reactions after initiation of cystic fibrosis combination modulator therapies
pubmed.ncbi.nlm.nih.gov
In the post-ETI period, psychiatric ADRs are the most prevalent ADR reported via the Yellow Card scheme. Despite an unclear mechanism, there is significant clinical relevance in counselling and...
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Inhaled Medications for Maintenance Therapy in Pediatric Noncystic Fibrosis Bronchiectasis
pubmed.ncbi.nlm.nih.gov
Several inhaled medications could be considered as maintenance therapies for pediatric patients with noncystic fibrosis bronchiectasis, with more robust evidence to support use of inhaled antipseud...
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Regulatory adverse drug reaction analyses support a temporal increase in psychiatric reactions after initiation of cystic fibrosis combination modulator therapies
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Neutrophil serine proteases in cystic fibrosis: role in disease pathogenesis and rationale as a therapeutic target
pubmed.ncbi.nlm.nih.gov
Chronic airway inflammation is a central feature in the pathogenesis of bronchiectasis (BE), which can be caused by cystic fibrosis (CFBE; hereafter referred to as CF lung disease) and non-CF-related...
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A survey of cystic fibrosis physicians' views on lung transplant referral in the era of elexacaftor/tezacaftor/ivacaftor
pubmed.ncbi.nlm.nih.gov
While physician knowledge about LTx referral indications appears improved since the CF referral guidelines were published, uncertainty about referral timing is pervasive, and the guidelines will need...
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Use of CFTR modulators in pregnancy: new information for neonatal, paediatrics and midwifery teams
pubmed.ncbi.nlm.nih.gov
Cystic fibrosis (CF) is common, multisystem, life-limiting genetic condition, predominantly in the Caucasian population. There have been recent advances in the management of CF, in particular in the...
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In vivo and in vitro analyses of the role of the Prc protease in inducing mucoidy in Pseudomonas aeruginosa
pubmed.ncbi.nlm.nih.gov
After colonizing the lungs of individuals with cystic fibrosis, Pseudomonas aeruginosa undergoes mutagenic conversion to a mucoid form, worsening the prognosis. Most mucoid isolates have a truncated...
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The Omega-6 Lipid pathway shift is associated with neutrophil influx and structural lung damage in early cystic fibrosis lung disease
pubmed.ncbi.nlm.nih.gov
Our data provide more insight into the lung lipidome of infants with CF, and show that a shift from LA derivatives to AA derivatives in BALF associates with early CF lung disease progression.
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CF Ferrets exposed to in utero ivacaftor do not develop lens abnormalities
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Clinical outcomes of two infants with cystic fibrosis, including presence of the vas deferens, born to a woman with cystic fibrosis taking CFTR modulators during both pregnancies
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Clinical and radiological improvement of cavitary Mycobacteroides abscessus disease in cystic fibrosis following initiation of elexacaftor/tezacaftor/ivacaftor
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