I reckon one of the best questions about #NOTACS was the about the CO2 footprint. It is highly plausible that HFNP was much worse for the environment. HFNP uses a lot of O2 and producing O2 results in a lot of CO2 emissions #CCR25

For any budding ICU Researchers out there - come work with us! Critical Care Medicine Academic/Clinical Fellowship - (commencing July 2025). See  https://t.co/R3GigFFewj Contact aislingmcmahon@mater.ie for further information.

The mass #MEDTwitter exodus to #medsky well and truly underway!

1/ The #Mater Misericordiae University Hospital is currently experiencing a systems problem which means that it cannot access patients’ Electronic Health Records.

https://t.co/nbgX9Hn5M6 we are recruiting our next SCF @NCCUCambridge. Fantastic opportunity to join our team & develop neurosciences and trauma icm expertise @vfjn2 @Menon_Cambridge @AriErcole @geoghep

At #CCR24 last week one method that came up was the #SlidingDichotomy method. But what is it and when might it be useful? 1/9 #MethodologyMonday #92

Study categorisation from @pocock_stuart at #PratoAnaes2022 ➡️ WOW! and PHEW! interpreted the same but very different ➡️ PHEW! and DAMN! interpreted differently but virtually the same We need to get wiser, a p-value is no substitute for brain.

I don’t think Rob Mac Sweeney gets enough plaudits for @CritCareReviews - his visionary approach to presenting, discussing, and disseminating new knowledge from critical care trials is ann incredible gift to humankind. Thanks Rob! #ccr24

Beyond one-size-fits-all in cardiogenic shock: microaxial flow pump, VA #ECMO or tailored use of mechanical circulatory support? 🫀VA ECMO should be reserved for selected patients with AMI & extreme CS 🫀 mAFP first? #Impella appears promising for CS due to STEMI & should be

I like how the 'Monday morning test' has become part and parcel of the discussions at #CCR24. Fascinating to hear how leaders in ICU integrate evidence into clinical practice. @CritCareReviews

Important caveat that some clinical outcomes of relevance (intubation, mortality) were not improved in patients receiving NIV. Health economic and environmental analyses needed. #CCR24

Impressive reduction in progression to severe respiratory failure in patients treated with protocolised early NIV in the #NAVIGATEtrial. #CCR24

I think this has been one of the most robust discussions I’ve heard at any #CCR meetings. Truly awesome. Massive kudos to all @CritCareReviews for creating this forum. #CCR24

Fantastic question about the ethics of when response adaptive randomisation goes wrong. Suitably robust response. Very clear that the @remap_cap authors acutely feel this and have taken great steps to ensure miscoding errors wont occur going forward. #CCR24

Where does this leave steroids for CAP? Results of REMAP-CAP at odds with those of CAPE COD. Meta-analysis required. #CCR24

Since @CritCareReviews and #CCR24 have had a couple of win ratio analyses, here’s a little plug for a video I made with @CMichaelGibson a few years back that is meant to be an accessible explainer of how it works. Please excuse my hair. It was a different time.

Are all ketones bad? @f_g_zampieri highlighting potential positive effects of ketones in patients with heart failure. Remains to be seen if there are other populations where ketones may improve organ function? https://t.co/VZ7LmVrOFa #CCR24

Several people have now raised the questions of the PK/PD properties of SGLT2is in the critically ill. Lots of work to do! #ccr24

@f_g_zampieri : we should revisit the ICU mantra of stopping all the patients home medications when critically unwell #CCR24

This seems to be the original description of the win ratio method. https://t.co/kOp2cExTNJ #ccr24