Axel Jensen Profile
Axel Jensen

@axel_jensen

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PhD student at Uppsala University, working with primate speciation and conservation genomics. Birder.

Uppsala, Sverige
Joined August 2011
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@axel_jensen
Axel Jensen
9 months
Very happy to share our new paper, now out in Nature Communications. We found an (adaptive?) Y chromosome introgression between ~6 million years divergent guenon species, which we think is pretty wild given Haldane’s rule etc. Check it out!.
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nature.com
Nature Communications - Interspecific hybrids tend to show a sex-specific reduction in fitness, thus limiting gene flow to loci inherited through the homogametic sex. Here, the authors identify a...
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@axel_jensen
Axel Jensen
1 year
RT @SamyukthaRajan: I’m so excited! My first-first author paper AND the first chapter of my PhD is now out in @CurrentBiology : ‘Translocat….
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@axel_jensen
Axel Jensen
1 year
More in the preprint, have a read! . With Emma Horton, Junior Amboko, Stacy-Anne Parke, John Hart, Anthony Tosi, @kguschan and Kate Detwiler. This is what the Y chromosome donor species, the blue monkey, looks like (although a female so no Y chrom in this picture…)
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@axel_jensen
Axel Jensen
1 year
as almost no introgression was present on the autosomes. This suggest that the introgressing Y chromosome swept to fixation from a very low initial frequency, which most likely required positive selection (we do some simulations to test this in the manuscript)….
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@axel_jensen
Axel Jensen
1 year
This means that they were some 6 million years diverged at the time of introgression. This appears to be quite exceptional, and we have not been able to find any comparable events in the literature. Interestingly, it also seems that the Y was the only thing to introgress. .
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@axel_jensen
Axel Jensen
1 year
Dent’s monkey, the easternmost lineage of the mona species group, carries a Y chromosome that is nested within the blue monkey. These lineages diverged ca 7-8 million years ago. We demonstrate that introgression was indeed the cause, and that it occurred ca 1-2 mya….
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@axel_jensen
Axel Jensen
1 year
This phenomenon is known as Haldane’s rule and effectively hinders the Y chromosome from introgressing (Y chromosome introgression is rare!). Indeed, we found that the Y chromosome phylogeny traced the species tree much closer than the mtDNA. With one pretty remarkable exception:.
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@axel_jensen
Axel Jensen
1 year
Knowing that males are more prone to disperse than females, the Y should in principle introgress as much or more than the maternally inherited mitochondrion. However, male hybrids, being heterogametic (in mammals), typically suffer reduced fitness relative to females….
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@axel_jensen
Axel Jensen
1 year
New preprint on a wild Y chromosome introgression between 6 my divergent primate species! .Guenons are a diverse group of African primates that hybridized a lot in the past. In this study, we looked at patterns of Y introgression….
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biorxiv.org
Hybridization between distinct lineages is widespread in nature, with important implications for adaptation and speciation. If hybrids are fertile, alleles can introgress across species boundaries....
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@axel_jensen
Axel Jensen
1 year
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@axel_jensen
Axel Jensen
1 year
After almost four years of scrutinizing their genotypes, I finally got some firsthand guenon phenotype experience during a wonderful wildlife tour in Kenya and Uganda. Turns out they’re adorable!
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@axel_jensen
Axel Jensen
2 years
RT @ElinVidevall: 📢 I'm looking for a PhD student to work on wolverine diet-microbiome associations with me at Uppsala University, Sweden.….
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@axel_jensen
Axel Jensen
2 years
RT @LinneaSmeds: Our paper about structural variants in inbred Scandinavian #wolves just came out in @EvolAppJournal! See 🧵 below on how we….
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@axel_jensen
Axel Jensen
2 years
RT @Garate_Olaizola: Internship oportunity for students from Uppsala University! Come work on ReCod!🐟🐟🐟.
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@axel_jensen
Axel Jensen
2 years
Summary in this thread:.
@axel_jensen
Axel Jensen
2 years
We have a new preprint to share. Hint: guenon evolution is a mess!. In my PhD project with @kguschan, we study guenon genomics to learn about speciation processes. In part 1, we focus on ancient hybridization, and found a lot of it. From the top: 1/15.
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@axel_jensen
Axel Jensen
2 years
Check out our recent @MolBioEvol paper! Includes lots of ancestral hybridization across deep branches, co-introgressing mitochondria and interacting nuclear loci, the (non)repeatability of introgression and more!.
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@axel_jensen
Axel Jensen
2 years
RT @Zoology_SU: Congratulations to @Kallekarlhugo for successfully nailing his thesis titled "Understanding evolutionary novelty through fe….
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@axel_jensen
Axel Jensen
2 years
. and turns out I needed one more. Not leaving you without some guenon pictures. These beauties are from @kguschan - there's a vervet, a Lhoest's and a red-tailed monkey - not sure which order they'll end up so take it as a challenge!
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@axel_jensen
Axel Jensen
2 years
That's it for now, there's more in the preprint though, read it and let us know your thoughts! And if you're going to the #smbe meeting in Ferrara, stop by my poster and chat! Big thanks to everyone involved in this project, really exciting to be able to share this now.
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