Antonio Wolff, MD (#HealthPolicyIsEconomicPolicy)
@awolff
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med onc @JHBreastGyn @HopkinsKimmel @HopkinsMedicine, @JohnsHopkins professor, @CLOSLER member. @ASCO fellow. @NCICTEP_ClinRes. @SusanGKomen scholar 🇧🇷/🇺🇲
Baltimore, MD
Joined April 2008
Why #ClinicalTrials? Because they matter. They help us develop the best interventions & treatments, and often ensure patients receive the best possible care. #BCSM #ItTakesAVillage @JHBreastGyn @hopkinskimmel
October is #breastcancerawarenessmonth. @awolff from @hopkinskimmel explains the benefit of clinical trials to both patients undergoing treatment and those who will be diagnosed in the future. #bcsm
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Don’t miss Dr. Erica Mayer (@elmayermd) presenting results from a Phase II study on neoadjuvant niraparib with dostarlimab for patients with BRCA- or PALB2-mutated #BreastCancer, focusing on the ER+/HER2- cohort, at the #SABCS24 Rapid Fire 3 session. @TheTBCRC 🗓️ Friday,
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#SABCS24 Dr. @awolff: Must study impact of new #cancer drugs on reproductive health. ⌛️ He believes we are under-utilizing ovarian suppression & over-utilizing chemo in premenopausal w/ #breastcancer, & window to answer this Q definitively in #bcsm #clinicaltrials is closing.
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Excited to see these @TheTBCRC presentations at SABCS 2024! -TBCRC 052: Does margetuximab provide benefit over trastuzumab in neoadjuvant HER2+ disease? -TBCRC 056: neoadjuvant PARP + IO in ER+ BRCA1/2 or PALB2 mut breast cancer? - and more!
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We are excited to have this trial open for patients with #metastatic #breastcancer treated an NCI community oncology practices #NCORP
@eaonc @awolff @ruthcarlosmd @ilana_graetz @LynneWagnerPhD
#ClinicalTrial EAQ221CD/CONCURxP monitors CDK4/6 inhibitor medication use with text message reminders & alerts for patients treated for #BreastCancer. For more information: https://t.co/AxfMpNdkef
#bcsm cc: @GelarehSadigh, @ilana_graetz
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It was a treat to do the Highlights of the Day I - Breast Ca Metastatic, and contextualize the great work of presenters and discussants. Thou shalt not forget to watch the fantastic talk by discussant @MayoClinic Dr. Ciara O'Sullivan.
Taking a moment to acknowledge that many places, especially in third world countries, lack access to essential drugs and resources. We are fortunate to have more in the US. A shout out to Dr. O’Sullivan for acknowledging that treatment paradigms are not applicable everywhere, we
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RxPONDER: AMH (low levels associated w/ diminished ovarian reserve) in women classified as premenopausal If low AMH --> no benefit from adj chemo If med/high AMH--> ⬆️4.4% in 5 yr DRFS w/ chemo Suggests:chemo impact may be due to impact on ovarian fxn @OncoAlert #ASCO24
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Dr. Nadine Tung discusses TBCRC048 at #ASCO24 - olaparib is effective in patients with MBC with inherited PALB2 mutation or tumor acquired BRCA1 or BRCA2 mutation. Benefit in initial trial confirmed in a larger group of patients @TheTBCRC @OncoAlert
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So grateful, @TarahBallinger. We are privileged that you chose to bring your brilliance to @eaonc and brighten the work we do to improve care for our patients. @NCICancerCtrl #ASCO24
@TarahBallinger @eaonc @awolff @LynneWagnerPhD @YAbdouMD Tarah, your presentation was just fantastic, and your work a true testament to your passion, commitment and skill. I am honored to work with you. Can’t wait to see what you will do next!!
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#TrialsThatImpactPatientCare Congratulations to the @eaonc EAZ171 Team! #ASCO24 See full press release https://t.co/VNM4tc4oP5 and simultaneous JCO paper
ascopubs.org
PURPOSEBlack women experience higher rates of taxane-induced peripheral neuropathy (TIPN) compared with White women when receiving adjuvant once weekly paclitaxel for early-stage breast cancer,...
Check out @JCO_ASCO Podcast: "EAZ171: Predictors of TIPN in Black women with #BreastCancer" w/ Dr. @ShannonWestin & Dr. @BryanSchne90417. EAZ171 was presented at the #ASCO24 Annual Meeting. @TarahBallinger @NCIprevention #NCORP @SusanGKomen @VBFoundation
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ETHAN - groundbreaking new @TheTBCRC trial for male breast cancer led by PI Dr. Pablo Leone. #ASCO24 Learn more at https://t.co/oD1sOu7g2e
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PI Dr. Tiffany Traina presenting the actively enrolling TBCRC058 trial #ASCO24 @RitaNandaMD Find more info at: https://t.co/WKuJM2KQ4A
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Tomorrow #ASCO24 check out @NTungMD present #TBCRC048 olaparib expanded cohorts of gPALB2 and sBRCA MBC, one of the most rewarding studies I’ve managed in the last decade and a testament to the power of investigator-initiated research @BIDMChealth @DFCI_BreastOnc @TheTBCRC
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TBCRC048 is a collaborative IST led by #DFHCC and was open at 11 academic centers across the US via @TheTBCRC - thank you to the incredibly dedicated study teams at each of the sites and, most importantly, the 114 participants, many of whom traveled great distances for the study
Tomorrow #ASCO24 check out @NTungMD present #TBCRC048 olaparib expanded cohorts of gPALB2 and sBRCA MBC, one of the most rewarding studies I’ve managed in the last decade and a testament to the power of investigator-initiated research @BIDMChealth @DFCI_BreastOnc @TheTBCRC
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As seen today at #ASCO24 - TBCRC026, HER2-E and tumors with increased immune signaling more likely to respond to HER2-directed therapy in ER-/HER2+ breast cancer treated with neoadjuvant HP without chemo. @TheTBCRC @HennessyMaeve
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TBCRC 049: Tucatinib, trastuzumab, capecitabine for HER2+ LMD -The first prospective LMD trial to show all of the following: -therapeutic drug levels in CSF -intracranial response -improvement in symptoms and QoL -extended OS compared to historical controls
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This is what qualifies for an oncologist to be in the presence of a rock star @NIHDirector ! #asco24 @judywawira @RamalingamMD
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Training & Promoting the next generation of breast cancer leaders, and of course designing the next generation of trials to improve patient outcomes.
A BIG thank you to the chairs and co-chairs of this year's #BIGNCTN Annual Meeting, notably: Drs David Cameron, @DrEricWiner, Boon Chua, @nlinmd
@BCRFcure @EU_HaDEA #EU4Health #bcsm
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What a trio of ACRA Award recipients, including @hopkinskimmel @JHBreastGyn Cesar Santa-Maria, MD! Congratulations to all in the Class of #ASCO24 @ConquerCancerFd awardees and their mentors! @ASCO
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