
ACCP CRIT PRN
@accpcritprn
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Promoting excellence and innovation in critical care pharmacy practice
Joined December 2015
Trying to find a place to highlight your pharmacy practice research? Check out our Conference & Abstracts Guide to help you plan and share your findings! You can find the full document in PDF form at under Research Resources #TwitterRX #PharmCrit #CritPRN
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#JournalWatch.Out of 208 patients including in this retrospective study, there were no incidences of methemoglobinemia when using iNO in adult cardiothoracic surgery ICU patients #AnnalsofPharmacotherapy @AnnalsofPharm
journals.sagepub.com
Background: Inhaled nitric oxide (iNO) is a selective pulmonary vasodilator utilized for the treatment of right ventricular dysfunction in the cardiac surgery p...
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Dr. Zoey Chasen, PharmD is the @ACCP Critical Care PRN Resident Trainee Spotlight for Q2. She has put in some amazing work this year, excited to see where she lands in the future!. #CritPRN #PharmICU @ACCPpostgrads
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Dr. Andrew Bennett, PharmD is the @ACCP Critical Care PRN Student Trainee Spotlight for Q2. He has put in some amazing work this year, excited to see where she lands in the future!. #CritPRN #PharmICU @ACCPpostgrads
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#JournalWatch.In older adults with septic shock, targeting a higher MAP of 80–85 mmHg increased mortality and adverse events vs 65–70 mmHg, despite early vasopressin use. OPTPRESS trial reinforces caution with aggressive vasopressor strategies. @yourICM.
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#JournalWatch.Admit to floor or ICU? This study published in Critical Care Explorations shows that machine learning (ML) models outperform traditional regression in predicting need for ventilation hospitalized patients with CAP. ML could enhance support clinical decision-making.
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#JournalWatch #critPRN In this retrospective study, preemptive phenobarbital monotherapy was associated with decreased mortality, mechanical ventilation, and adjunctive sedative medication use compared with symptom triggered BZDs
journals.sagepub.com
Background: The standard of care for alcohol withdrawal syndrome (AWS) is symptom-triggered benzodiazepines. There is an interest in utilizing phenobarbital fir...
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Burn injuries drastically alter PK/PD, complicating med dosing & monitoring. Pharmacists are key to optimizing therapy, guiding TDM, & driving antimicrobial stewardship in this complex population. #critPRN
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#JournalWatch In patients presenting with AIS within 4.5 hours, those who received TNK+ mechanical thrombectomy vs mechanical thrombectomy alone, had higher rates of functional independence at 90 days
nejm.org
The safety and efficacy of treatment with intravenous tenecteplase before endovascular thrombectomy in patients with acute ischemic stroke due to large-vessel occlusion remain uncertain. In this op...
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#JournalWatch #critPRN.Go-live of premade alteplase kits for high-risk pulmonary embolism causing cardiac arrest shortens the time for meds to arrive to bedside for administration during cardiac arrest.
academic.oup.com
The basis of cardiac arrest management involves quality chest compressions, early defibrillation, and immediate treatment of any potential reversible cause
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🫁 Inhalation injury can complicate burn care. Early intubation, pulmonary hygiene, and toxicology management (CO, HCN, MetHb) are key. Pharmacists assist with antidotes, sedation, and ventilation strategies. #critPRN
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🔥 Burn injuries trigger a profound hypermetabolic response—elevating energy needs, driving catabolism, and increasing demand for protein, calories, and micronutrients. Pharmacists play a key role in optimizing nutrition and recovery #critPRN
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#JournalWatch .In the REMAP-CAP trial, a 7-day course of IV hydrocortisone in ICU patients with CAP did not significantly reduce 90-day mortalit. The trial arm was stopped early for futility. Modest reduction in shock duration observed
link.springer.com
Intensive Care Medicine - To determine whether hydrocortisone improves mortality in severe community-acquired pneumonia (CAP). In an international adaptive randomized controlled platform trial...
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Managing burns includes proper fluid resuscitation and nutrition support. Check out this infographic for key burn fluid formulas and nutrition tips. More insights on tackling hypermetabolism coming soon! #critPRN
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#JournalWatch Is faster better? Controversy exists on how fast septic patients should receive 30ml/kg crystalloid? When compared with fluid within 1 hr, this study found that 30ml/kg crystalloid within 2-3h had lower mortality & intubation @CritCareExplore.
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#JournalWatch 🚨 New data on high-risk PE 🚨.Advanced recanalization with systemic thrombolysis, surgical thrombectomy, or catheter-directed treatments may significantly improve short-term survival vs. using VA-ECMO alone as a bridge to recovery
link.springer.com
Intensive Care Medicine - High-risk acute pulmonary embolism (PE) is a life-threatening condition necessitating hemodynamic stabilization and rapid restoration of pulmonary perfusion. In this...
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#JournalWatch Despite being associated with diabetes control, weight loss, and ASCVD benefit, researchers found that increased GLP-1 levels were associated with increased 90-day mortality in critically ill patients with acute respiratory failure.
journals.lww.com
levels indicate disease severity and clinical outcomes in patients with acute respiratory failure, a common cause of critical illness. DESIGN: Retrospective cohort study. SETTING: ICUs in UPMC Health...
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