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Yuriy Pichugin Profile
Yuriy Pichugin

@ab_in_

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Theoretical biologist, still slightly physicist. Project lead @MPI_EvolBio. Open-ended evolution, eco-evolutionary feedbacks, life cycles.

Joined March 2017
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@ab_in_
Yuriy Pichugin
5 months
RT @yuanxiao_gao: Excited to share our latest theoretical work on how irreversible cell differentiation evolves under changing cell divisio….
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www.nature.com
Scientific Reports - Evolution of irreversible differentiation under stage-dependent cell differentiation
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@ab_in_
Yuriy Pichugin
6 months
Nine PhD positions are open at Max Planck Institute. Come to work with me on modeling of the origins of organismic complexity at the onset of multicellular life. Application deadline is January 26.
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@ab_in_
Yuriy Pichugin
8 months
RT @tmbiosci: For biologists, philosophers of biology, and cognitive scientists, the Evolving Individuality 2024 conference will run @ Macq….
pierrickbourrat.github.io
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@ab_in_
Yuriy Pichugin
9 months
RT @RicardoMtzG: I am looking for a PhD student to join our work at @CASUSscience and work on ecological pattern formation. The project is….
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@ab_in_
Yuriy Pichugin
9 months
RT @mariakleshnina: PhD opportunity! 🥳Interested in game theory, ecology and evolution? Want to make a difference and change how we think a….
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@ab_in_
Yuriy Pichugin
2 years
RT @chilbe3: 🚨 We are looking for two (!) PhD students to join our group. One project is on modeling cooperation in changing environments.….
www.evolbio.mpg.de
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@ab_in_
Yuriy Pichugin
2 years
RT @BenjaminWerner_: We have an opening for two post doc positions here in sunny London to work on the evolution of extra-chromosomal DNA i….
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@ab_in_
Yuriy Pichugin
2 years
RT @Uni_WUE: Welcome to JMU @GokhaleCS! As new professor for Theoretical #Biology Chaitanya Gokhale develops scientific theories on the mos….
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@ab_in_
Yuriy Pichugin
2 years
RT @wc_ratcliff: @CurrentBiology just published two cool papers on the role of life cycles in the evolution of multicellularity. One by @Ev….
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@ab_in_
Yuriy Pichugin
2 years
Have a look at our new story on how cyanobacteria alter their environment and the environment in turn shapes the life cycle of that cyanobacteria.
@Hammerschmidt_K
Katrin Hammerschmidt
2 years
First part of Si Tang’s PhD in collaboration with @ab_in_ : An environmentally induced multicellular life cycle of a unicellular cyanobacterium. Just out in @CurrentBiology .Free version here:
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@ab_in_
Yuriy Pichugin
3 years
RT @geeklhem: Take a deep dive in Evolutionary transitions in individuality along with a diverse community of experimentalists, philosopher….
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@ab_in_
Yuriy Pichugin
3 years
RT @ernestoberriosc: We are excited to announce a symposium on the mathematical modelling of resistance evolution (bacteria and cancer) at….
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@ab_in_
Yuriy Pichugin
3 years
Still, if we ask which life cycles can be evolutionary stable (i.e. cannot be invaded from rare), their diversity is exactly predicted by the previous model with unconstrained growth. So, that much simpler model is not too bad after all. 7/7.
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@ab_in_
Yuriy Pichugin
3 years
The composition of these, i.e. a bi-stability between different combinations of coexisting life cycles is a thing too. 6/7.
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@ab_in_
Yuriy Pichugin
3 years
We found that there is no such thing as an "optimal life cycle" in this model - the end state of the population dynamics may depend on the initial conditions (bi-stability). The end state may be a coexistence of several life cycles. 5/7.
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@ab_in_
Yuriy Pichugin
3 years
Here, we added competition between colonies, so the growth pattern changed from exponential to logistic one. Most of the nice math we had before went out the window. Still, the few remained properties were useful enough to reconstruct the beautiful dynamics of the system. 4/7.
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@ab_in_
Yuriy Pichugin
3 years
There are some mathematically beautiful and, at the same time, biologically meaningful results coming from this model. However, these results assume that resources and space are infinite and the best life cycle is the one that grows faster than every other. 3/7.
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@ab_in_
Yuriy Pichugin
3 years
The model at the core of the theory is simple: when cells divide, they are stuck together, and the resulting cell colony grows until it fragments into smaller pieces. Colonies change their properties with size, so some fragmentation patterns are better than others. 2/7.
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@ab_in_
Yuriy Pichugin
3 years
Our work with Vanessa Ress and @EvolTheoArne on the interplay between evolution and ecology of multicellular life cycles is out! Here, we extend the theory of clonal life cycles evolution by adding competitive interactions between colonies. 1/7.
elifesciences.org
The evolution of clonal multicellular life cycles, whose growth is constrained by competition, may lead to coexistence or multistability between several life cycles while evolutionarily stable...
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