Dr Alexandra Iordachescu
@a_iordachescu
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Scientist/academic @unibirmingham . Bone, organoids, extreme environments and 3Rs research. Views are my own.
Joined October 2017
5 News has been given special access to interplanetary research, called the Bio-SPHERE project, taking place more than 1km below the North Yorkshire countryside. @peterofthelane went to check it out. @STFC_Matters | @iclboulby | @unibirmingham
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Outer space …. underground. A fascinating story coming up on @5_News at 5pm today about the Bio-SPHERE project, more than 1km below the North Yorkshire countryside. Big thanks to @STFC_Matters @iclboulby and @unibirmingham for making it happen.
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We have an exciting PhD studentship available with @a_iordachescu (Bham) and me (Notts) developing a new type of bone graft that harnesses the ability to control cell behaviour through their physical environment. Fully-funded ( @The_MRC ) for 4 years. 🦴📷📷
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Deadline for applications: midday (GMT) 12 January 2024. Interviews w/c 26 Feb. Shortlisting: by 9 February. For details and informal discussions: robert.owen@nottingham.ac.uk & a.iordachescu@bham.ac.uk @UoN_BDI @Impact_Aim_Mrc @ChemEngBham @eps_unibham @HTIbham
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We have an exciting PhD studentship available with @RobertEOwen (Notts) and me (Bham) developing a new type of bone graft that harnesses the ability to control cell behaviour through their physical environment. Fully-funded (@The_MRC) for 4 years. 🦴🩻🧫🔬 https://t.co/SvymsCsXPc
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In her latest publication, Alex considers what the impact of microgravity on tissues might mean for future space missions.
With special thanks to the collaborators, the reviewers, the journal and the funders @natureportfolio @ChemEngBham @HTIbham @neileisenstein @GarethApplebyT1 @CranfieldDefSec @NC3Rs
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Did you know the 3Rs is not only international, but intergalactic? Through her Training Fellowship, @a_iordachescu developed an in vitro method to simulate skeletal tissue degeneration, which can be caused by ageing, disease and weightlessness in space:
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With special thanks to the collaborators, the reviewers, the journal and the funders @natureportfolio @ChemEngBham @HTIbham @neileisenstein @GarethApplebyT1 @CranfieldDefSec @NC3Rs
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Pleased to share our latest publication in @Nature_NPJ Microgravity, investigating the role of bioengineered tissues for research & damage mitigation during extended space operations - part of our work into biosystems in extreme environments 🧫🔬🦴🚀🪐 https://t.co/cNY9idT2vx
nature.com
npj Microgravity - Space habitats for bioengineering and surgical repair: addressing the requirement for reconstructive and research tissues during deep-space missions
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Just over 3 weeks remaining to apply for this fantastic PhD studentship looking at the response of composite materials under hyper-velocity impacts☄️🚀, supervised by @GarethApplebyT1 and myself @HTIbham @ChemEngBham @CranfieldDefSec
https://t.co/MhY3kD8N8p
findaphd.com
PhD Project - On the failure of composite panels under hyper-velocity at Cranfield University, listed on FindAPhD.com
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I am pleased to offer an exciting, fully-funded @EPSRC PhD studentship with @GarethApplebyT1 between @CranfieldDefSec, @ChemEngBham and @QinetiQ looking at the response of composite materials to hypervelocity impacts ☄️. Application deadline 22 August https://t.co/ST2BH8BLNU
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I am very grateful to have received this funding from the @NC3Rs and excited to start working with @DWard2040 at @FBMH_UoM to apply my bone organoids for studying mineral sensing in skeletal physiology and disease
Four awards supporting 3Rs method transfer and uptake have been made as part of our Skills and Knowledge Transfer grant scheme. Projects include a co-funded award with @CRUKresearch to support uptake of a 3D culture system for mouse and human epithelia:
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A new @unibirmingham and @CranfieldUni consortium will investigate how extreme environments affect human biology. Led by @a_iordachescu, projects will study tissue loss in a simulated microgravity environment and the shock response of tissues - and more 👇 https://t.co/IGf9uwbCp4
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Tomorrow, @unibirmingham is launching a new consortium with @CranfieldUni to explore the effects of extreme environments on human biology: https://t.co/2bW36zivdw
@ChemEngBham @a_iordachescu
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📢| Tomorrow we are launching a new consortium with @CranfieldUni to explore the effects of extreme environments on human biology @eps_unibham @ChemEngBham @a_iordachescu
https://t.co/run9lkEk0s
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Just released a Behind-The-Paper article on the @Nature_NPJ Microgravity website describing the technical and clinical contexts for developing trabecular bone organoids @NC3Rs @Metcalfe_AD
https://t.co/a5f7phblWG
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With big thanks to the funders for the award, the publisher and collaborators @Metcalfe_AD @DWLiam @3rdfloorlab @erikhughes20
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Pleased to share the results from my @NC3Rs project – ‘Trabecular bone organoids: a micron-scale ‘humanised’ prototype designed to study the effects of microgravity and degeneration’, published today in @Nature_NPJ Microgravity. https://t.co/dhWmoPAlx0
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Another of our Training Fellows, Dr Alexandra Iordachescu @a_iordachescu, is developing a 3D in vitro bone model that could replace the use of animals to study bone loss, including that experienced by astronauts in microgravity! #WomenInScience
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Fantastic evening at my former department @KingsCollegeLon - started with a great talk from Prof Steve Harridge on muscle atrophy in microgravity followed by two inspirational talks from astronauts Dr Mike Foale CBE and Tony Antonelli @ISSET_STEM @pintofscience
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