RT @JGrutzendler: 1/ I am happy to share our latest publication in Nature Neuro We present the first subcellula….

RT @JGrutzendler: 🧵 New from our lab! Led by outstanding research scientist @YifeiCai_, we optimized Antibody-Driven Proximity Labeling for….

Many thanks to the generous support of my mentors.@JGrutzendler , Angus Nairn, and many amazing collaborators @Iguaracysousa @mslob95 and funding from the NIH,@embl @_BrightFocus @alzassociation , Yale/NIDA Neuroproteomics Center, and Yale ADRC.

In our most recent paper, we uncover the myelin-axon interactome in human brains and reveal molecular perturbations and structural disruptions at the myelin-axon interface in Alzheimer’s disease @JGrutzendler @e_petsalaki @reimand .

This study was made possible by the generous support of my mentors @JGrutzendler, @kristenbrennand and Angus Nairn, as well as many amazing collaborators and funding from the NIH, @_BrightFocus, @alzassociation, Yale/NIDA Neuroproteomics Center, and Yale ADRC.

Excited to share that two studies from my postdoc research were published back to back! In the first, we uncovered the molecular basis of axon spheroids—a key hallmark of Alzheimer's disease—and demonstrated their potential reversibility.