Matthias Wilk
@WilkMatthias
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Delighted to share our latest work @Brown_lab1, developing Perturb-map: a platform enabling CRISPR genomics with spatial resolution in tissue sections @SinaiImmunol @IcahnInstitute @SinaiGenetics
https://t.co/gXm20dTlS8 A thread!👇(1/12)
biorxiv.org
The cellular architecture of a tumor, particularly immune composition, has a major impact on cancer outcome, and thus there is an interest in identifying genes that control the tumor microenvironment...
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Excited to see our new xenograft model for Langerhans Cell Histiocytosis published in @Bloodadvances. It reproduces key features of human LCH and serves as a preclinical model system.
BRAFV600E or mutant MAP2K1 human CD34+ cells establish Langerhans cell–like histiocytosis in immune-deficient mice https://t.co/XLJujQlyIE
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Clonal hematopoiesis in donors and long-term survivors of related allogeneic hematopoietic stem cell #transplantation
https://t.co/xyKnLuwLrX
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This Preprint Watch in @NatRevImmunol highlights the impact of coronaviruses on the complement system – a new therapeutic target? @MiriamMerad @SinaiImmunol
Coronaviruses hijack the complement system
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