Wakeling Lab
@WakelingLab
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Neuromuscular Mechanics Lab @SFU. We study the mechanics of skeletal muscle using both #experiments and #modelling. PI: James Wakeling
Burnaby, British Columbia
Joined May 2018
We’re hiring! 2-year fully funded postdoc with Friedl De Groote @FriedlDeGroote at KU Leuven in collab with Nilima Nigam @SFUMath and Steph Ross @stealiceross on predictive MSK simulations to test advanced muscle models during cycling and gait:
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Some great posters by the lab at the @TheSIAMNews PNW Conference on parallel computing (Javier Almonacid), 3D dynamic muscle modelling (Cassidy Tam), and modelling effects of cerebral palsy (@rnkonno)!
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@rnkonno @stealiceross 3/ Often cerebral palsy affected muscle has longer sarcomere lengths than typical muscle. We find that the effects from the longer sarcomeres are mitigated by increased volume fractions of extracellular matrix
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@rnkonno @stealiceross 2/ We found that the change in extracellular matrix volume fraction during cerebral palsy results in a larger increase in stiffness compared to the change in sarcomere length
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1/ Using a 3D continuum model for muscle, we investigated the influence of microstructural components of muscle including the extracellular matrix and sarcomeres on whole muscle passive stiffness
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A new paper out from the lab modelling the effects of cerebral palsy on skeletal muscle mechanics led by @rnkonno @stealiceross
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Have some muscle modeling work you’d like to share? Submit an abstract to #WCB2022 for the session Dynamic Muscle Modeling (in MSK 3: Modeling and Simulation) that I’m moderating with Tobias Siebert and James Wakeling! Deadline is Nov 15th at 23:59 GMT+8
We hope this hybrid format would allow biomechanists around the world to participate with minimal interference from the effects of the pandemic. Whether you plan to join us online or onsite, we look forward to receiving your abstracts by Nov. 15! More info on WCB 2022 website!
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New work by @pratt_jaylene reveals information in EMG signals persists across consecutive pedal cycles!
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1/ The fifth and final paper from my PhD thesis is out now in Interface! In this paper, we examined the effects of muscle mass on contraction efficiency. More details in thread ⬇️ @WakelingLab
https://t.co/zyjvDpu3H6
royalsocietypublishing.org
While skeletal muscle mass has been shown to decrease mass-specific mechanical work per cycle, it is not yet known how muscle mass alters contraction efficiency. In this study, we examined the effect...
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7/last Please follow Steph at @stealiceross to stay up to date with her research!
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6/ What's next for Steph? A postdoc at UBC, and fifth paper in review! Watch out for her work on the effects of muscle mass on the metabolic cost and efficiency of contraction, and how these relationships are impacted by tendon stiffness. We are so proud of her phenomenal work.
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5/ Her final paper, "The energy of muscle contraction. III. Kinetic energy during cyclic contractions" is one of a three-part trilogy on muscle energy, using a dynamic continuum model of muscle that accounts for the non-trivial effects of kinetic energy!
frontiersin.org
During muscle contraction, chemical energy is converted to mechanical energy when ATP is hydrolysed during cross-bridge cycling. This mechanical energy is th...
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4/ The third, "Added mass in rat plantaris muscle causes a reduction in mechanical work", discovered tissue mass decreases the work a muscle produces at larger muscle sizes.
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3/"Size, history-dependent, activation and three-dimensional effects on the work and power produced during cyclic muscle contractions", found a range of contractile properties often unaccounted for in modeling significantly affect muscle work and power!
academic.oup.com
Abstract. Muscles undergo cycles of length change and force development during locomotion, and these contribute to their work and power production to drive
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2/ Her first, "A modelling approach for exploring muscle dynamics during cyclic contractions" developed a framework to test modifications to Hill-type muscle models that incorporate aspects of muscle function typically ignored in modeling.
journals.plos.org
Author summary One of the primary functions of skeletal muscle is to generate work and power to move the body during locomotor tasks such as walking and running. Because it is difficult to measure...
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1/ Congratulations to Dr. Stephanie Ross who successfully defended her thesis on the effects of muscle tissue mass on contractile performance! Steph had an immensely productive PhD, publishing four impactful papers!
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Ryan Konno is a @SFU 2019/20 recipient of Special Graduate Entrance Scholarship. Learn more about Ryan and their research in @SFU_Science. https://t.co/vBAavmVesg
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The (muscle) force is with us! Flexing 2 decades of research, @SFU BPK professor James Wakeling’s work offers insights into training & recovery, better prosthetics and robotics in the #SFUScholarlyImpact of the Week: https://t.co/caKtKBXVAx
#SFUResearch
@SFU_Science @WakelingLab
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It is an honor to announce the @CAIMS_SCMAI CAIMS-Fields Industrial Mathematics Prize for Prof. Nilima Nigam (SFU) for broad-ranging contributions and outstanding national leadership in the discipline of industrial mathematics.
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And @pratt_jaylene explored the Entropic Half-Lifes of simulated and real EMG intensities (3/3)
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