ToxGenSolutions
@ToxGenSolutions
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TGS applies technologies, pathways of toxicity and common nodes of toxicity representing the core promise and value of the applied systems toxicology paradigm.
Maastricht, The Netherlands
Joined October 2016
Here, an AOP network incorporating a recently proposed tau-driven AOP toward memory loss.(AOP429) related to sporad
www.growkudos.com
The adverse outcome pathway (AOP) concept was first proposed as a tool for chemical hazard assessment facilitating the regulatory decision-making in toxicology and was more recently recommended...
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iPSC-derived neurons as in vitro models to identify Alzheimer's and AD-related molecular mechanisms.
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The molecular and cellular data on Alzheimer's disease and neurotoxicity that are available in the public domain we
www.growkudos.com
The molecular and cellular data on Alzheimer's disease and neurotoxicity that are available in the public domain were structured according to key events describing toxic tau-protein mediated memory...
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Moving towards a probabilistic risk assessment approach without animal experimentation. The aim is to develop a pro
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Sporadic #Alzheimer’s disease and neurotoxicity-related microRNAs affecting KEs of the tau-driven AOP toward memory
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Genetic analysis of human iPSC derived neurons exposed to selected environmental risk factors and biopsies from Alzheimer’s patients and control individuals revealed processes that were not seen in control individuals. Currently, 9 miR’s are under further evaluation.
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ToxGenSolutions represented the Interreg. project ''Herinneringen'' (''Memories'') at the 29th Alzheimer's Europe Congress in The Hague.
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#ToxGenSolutions represented the #Interreg. project ''Herinneringen'' (''Memories'') at the 29th #Alzheimer's Europe Congress in The Hague. A poster was presented showing the #animalfree approach...
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The INTERREG Vlaanderen-Nederland project ''Herinneringen'' (''Memories'') organises its 2019 Symposium STOP ALZHEIMER on Monday December 16 in the wonderful 'Promotiezaal' of the Katholieke Universiteit Leuven (Naamsestraat 22, 3000 Leuven).
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#ToxGenSolutions applying #animalfree approaches to address #Alzheimers initiation by #environmental #risk factors.
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Invitation to the 2019 Symposium: The #interreg project #Herinneringen applies #animalfree approaches to understand the #adverseoutcomepathways (#AOP) driving sporadic #alzheimersdisease.
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‘’A global investigation reveals the rising human toll of lax controls and testing standards pushed by a booming industry’’ (by ICIJ, 25.11.2018). November saw several similar articles being released by various media. The #nonanimal #ToxGenSolutions view:
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‘’A global investigation reveals the rising human toll of lax controls and testing standards pushed by a booming industry’’ (by ICIJ, 25.11.
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The #Interreg. project #Herinneringen validated its concept by rebuilding the arguments as to why #nonanimal methods lead the way towards early diagnosis of, and new drug target development for, early sporadic #Alzheimers. The presentations are soon on
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The #Interreg project #Herinneringen invites you to its annual meeting to discuss strategies and progress related to the development of a cost effective minimally invasive test for diagnosis of #alzheimers disease before brain damage occurs. For info:
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Full house for both presentations of the #NAM project #Memories (#Herinneringen) during the #PAS 2018 Festival in Maastricht.
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Preventing #alzheimersdisease through human relevant #NAM based #Alzheimer research. Interreg. Project ‘’Herinneringen’’, September 8 (21:15 and 22:15) during the PAS Festival in Maastricht.
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Private-public funded innovation looking at #Alzheimer’s disease initiation and development in a #nonanimal way.
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Decades of #Alzheimer's (AD) research has been unsuccessful in controlling amyloid plaque development and resulting cellular processes leading to clinical AD. The project #HERINNERINGEN applies #nonanimal toxicogenomics to fill out gaps in our understanding of early AD induction.
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